METTL3 Regulates Angiogenesis by Modulating let-7e-5p and miRNA-18a-5p Expression in Endothelial Cells
(2021)
Journal Article
Chamorro-Jorganes, A., Sweaad, W. K., Katare, R., Besnier, M., Anwar, M., Beazley-Long, N., …Emanueli, C. (2021). METTL3 Regulates Angiogenesis by Modulating let-7e-5p and miRNA-18a-5p Expression in Endothelial Cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 41(6), e325-e337. https://doi.org/10.1161/atvbaha.121.316180
Objective:
Postnatal angiogenesis is critical in vascular homeostasis and repair. m6A RNA methylation is emerging as a new layer for fine-tuning gene expression. Although the contribution of the m6A-catalyzing enzyme, METTL3 (methyltransferase-like...
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