Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression

Hassawi, Mona; Shestakova, Elena A.; Fournier, Marilaine; Lebert-Ghali, Charles-�tienne; Vaisson, Gratianne; Frison, H�lo�se; Sinnett, Daniel; Vidal, Ramon; Thompson, Alexander; Bijl, Janet J.

doi:10.1002/dvdy.24056

Research Repository

All Outputs (2)

c-Met inhibition in aHOXA9/Meis1model of CN-AML (2013)
Journal Article

Background: Hematopoiesis is a paradigm for developmental processes, hierarchically organized, with stem cells at its origin. Hematopoietic stem cells (HSCs) replenish progenitor and precursor cells of multiple lineages, which normally differentiate... Read More about c-Met inhibition in aHOXA9/Meis1model of CN-AML.

Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression (2013)
Journal Article

Background: The fusion protein E2A-PBX1 induces pediatric B cell leukemia in human. Previously, we reported oncogenic interactions between homeobox (Hox) genes and E2A-PBX1 in murine T cell leukemia. A proviral insertional mutagenesis screen with our... Read More about Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression.