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All Outputs (112)

COVID-19 vaccine hesitancy in care home staff: A survey of Liverpool care homes (2023)
Journal Article
Tulloch, J. S., Lawrenson, K., Gordon, A. L., Ghebrehewet, S., Ashton, M., Peddie, S., & Parvulescu, P. (2023). COVID-19 vaccine hesitancy in care home staff: A survey of Liverpool care homes. Vaccine, 41(7), 1290-1294. https://doi.org/10.1016/j.vaccine.2023.01.009

Uptake of COVID-19 vaccine first doses in UK care homes has been higher among residents compared to staff. We aimed to identify causes of lower COVID-19 vaccine uptake amongst care home staff within Liverpool. An anonymised online survey was distribu... Read More about COVID-19 vaccine hesitancy in care home staff: A survey of Liverpool care homes.

Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial (2022)
Journal Article
Bath, P. M., Skinner, C. J. C., Bath, C. S., Woodhouse, L. J., Areti, A., Korovesi, K., …Gordon, A. L. (2022). Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial. European Geriatric Medicine, 13, 1343-1355. https://doi.org/10.1007/s41999-022-00714-5

Purpose
Infections cause considerable care home morbidity and mortality. Nitric oxide (NO) has broad-spectrum anti-viral, bacterial and yeast activity in vitro. We assessed the feasibility of supplementing dietary nitrate (NO substrate) intake in ca... Read More about Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial.

Promoting continence in older people (2022)
Journal Article
Schlögl, M., Umbehr, M. H., Habib, M. H., Wagg, A., Gordon, A. L., & Harwood, R. (2022). Promoting continence in older people. Age and Ageing, 51(9), Article afac199. https://doi.org/10.1093/ageing/afac199

The prevalence of urinary incontinence (UI) is strongly associated with increasing age. Twenty five percent of women over 80 years of age have clinically significant symptoms in population surveys, but prevalence is as high as 70% in older hospital i... Read More about Promoting continence in older people.

Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study) (2022)
Journal Article
Shepherd, V., Islam, I., Wood, F., Williamson, P. R., Goodman, C., Bath, P. M., …Hood, K. (2022). Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study). BMC Geriatrics, 22(1), Article 710. https://doi.org/10.1186/s12877-022-03395-8

Background: People living in care homes have experienced devastating impact from COVID-19. As interventions to prevent the transmission of COVID-19 are developed and evaluated, there is an urgent need for researchers to agree on the outcomes used whe... Read More about Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study).

General practitioners' role in improving health care in care homes: a realist review (2022)
Journal Article
Chadborn, N. H., Devi, R., Goodman, C., Williams, C. D., Sartain, K., & Gordon, A. L. (2022). General practitioners' role in improving health care in care homes: a realist review. Family Practice, 40(1), 119-127. https://doi.org/10.1093/fampra/cmac071

Background:

Despite recent focus on improving health care in care homes, it is unclear what role general practitioners (GPs) should play. To provide evidence for future practice we set out to explore how GPs have been involved in such improvement... Read More about General practitioners' role in improving health care in care homes: a realist review.

Mandatory vaccination against COVID-19 for health and social care workers caring for older people (2022)
Journal Article
Gordon, A. L., Achterberg, W. P., & van Delden, J. J. M. (2022). Mandatory vaccination against COVID-19 for health and social care workers caring for older people. Age and Ageing, 51(4), Article afac097. https://doi.org/10.1093/ageing/afac097

The COVID-19 pandemic has particularly adversely affected older people with frailty and functional dependency. Essential regular contact with care staff has been evidenced as an important source of infection for this group. Vaccinating care staff can... Read More about Mandatory vaccination against COVID-19 for health and social care workers caring for older people.

'Don't let the trial kill the intervention': how can researchers and care home teams implement complex intervention trials in care homes? (2022)
Journal Article
Shenkin, S. D., Gordon, A. L., Johnston, L., Henderson, C., & Achterberg, W. P. (2022). 'Don't let the trial kill the intervention': how can researchers and care home teams implement complex intervention trials in care homes?. Age and Ageing, 51(3), Article afac068. https://doi.org/10.1093/ageing/afac068

The profile of care homes has never been higher, and not necessarily for the best reasons[1]. The COVID-19 pandemic has had, and continues to have, a massive impact on care home residents[2] , their families, the staff and organisations who care for... Read More about 'Don't let the trial kill the intervention': how can researchers and care home teams implement complex intervention trials in care homes?.

Developing a minimum data set for older adult care homes in the UK: exploring the concept and defining early core principles (2022)
Journal Article
Burton, J. K., Wolters, A. T., Towers, A. M., Jones, L., Meyer, J., Gordon, A. L., …Goodman, C. (2022). Developing a minimum data set for older adult care homes in the UK: exploring the concept and defining early core principles. Lancet Healthy Longevity, 3(3), e186-e193. https://doi.org/10.1016/S2666-7568%2822%2900010-1

Reforms to social care in response to the COVID-19 pandemic, in the UK and internationally, place data at the heart of proposed innovations and solutions. The principles are not well established of what constitutes core, or minimum, data to support c... Read More about Developing a minimum data set for older adult care homes in the UK: exploring the concept and defining early core principles.

Contextual factors influencing complex intervention research processes in care homes: A systematic review and framework synthesis (2022)
Journal Article
Peryer, G., Kelly, S., Blake, J., Burton, J. K., Irvine, L., Cowan, A., …Goodman, C. (2022). Contextual factors influencing complex intervention research processes in care homes: A systematic review and framework synthesis. Age and Ageing, 51(3), Article afac014. https://doi.org/10.1093/ageing/afac014

Background: Care homes are complex settings to undertake intervention research. Barriers to research implementation processes can threaten studies' validity, reducing the value to residents, staff, researchers and funders. We aimed to (i) identify an... Read More about Contextual factors influencing complex intervention research processes in care homes: A systematic review and framework synthesis.

The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure (2022)
Journal Article
Gordon, A. L., Rick, C., Juszczak, E., Montgomery, A., Howard, R., Guthrie, B., …Tate, V. (2022). The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure. Age and Ageing, 51(3), Article afac052. https://doi.org/10.1093/ageing/afac052

The COVID-19 pandemic resulted in catastrophic levels of morbidity and mortality for care home residents. Despite this, research platforms for COVID-19 in care homes arrived late in the pandemic compared with other care settings. The Prophylactic The... Read More about The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure.

Effect of perindopril or leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial (2022)
Journal Article
The LACE study group, Achison, M., Adamson, S., Akpan, A., Aspray, T., Avenell, A., …Witham, M. D. (2022). Effect of perindopril or leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial. Journal of Cachexia, Sarcopenia and Muscle, 13(2), 858-871. https://doi.org/10.1002/jcsm.12934

BACKGROUND: This trial aimed to determine the efficacy of leucine and/or perindopril in improving physical function in older people with sarcopenia. METHODS: Placebo-controlled, parallel group, double-blind, randomized two-by-two factorial trial. We... Read More about Effect of perindopril or leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial.

The uptake and use of a minimum data set (MDS) for older people living and dying in care homes: a realist review (2022)
Journal Article
Musa, M. K., Akdur, G., Brand, S., Killett, A., Spilsbury, K., Peryer, G., …Goodman, C. (2022). The uptake and use of a minimum data set (MDS) for older people living and dying in care homes: a realist review. BMC Geriatrics, 22(1), Article 33. https://doi.org/10.1186/s12877-021-02705-w

Background: Care homes provide long term care for older people. Countries with standardised approaches to residents’ assessment, care planning and review (known as minimum data sets (MDS)) use the aggregate data to guide resource allocation, monitor... Read More about The uptake and use of a minimum data set (MDS) for older people living and dying in care homes: a realist review.

Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey (2021)
Journal Article
Hoedl, M., Eglseer, D., Bernet, N., Everink, I., Gordon, A. L., Lohrmann, C., …Bauer, S. (2022). Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey. Journal of Nursing Scholarship, 54(4), 462-469. https://doi.org/10.1111/jnu.12758

Purpose: Falls are a highly prevalent problem in hospitals and nursing homes with serious negative consequences such as injuries, increased care dependency, or even death. The aim of this study was to provide a comprehensive insight into institution-... Read More about Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey.

Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance (2021)
Journal Article
van Haastregt, J. C., Everink, I. H. J., Schols, J. M. G. A., Grund, S., Gordon, A. L., Poot, E. P., …Achterberg, W. P. (2022). Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance. European Geriatric Medicine, 13(1), 291-304. https://doi.org/10.1007/s41999-021-00575-4

Purpose: To describe a guidance on the management of post-acute COVID 19 patients in geriatric rehabilitation. Methods: The guidance is based on guidelines for post-acute COVID-19 geriatric rehabilitation developed in the Netherlands, updated with re... Read More about Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance.

GPs’ involvement to improve care quality in care homes in the UK: a realist review (2021)
Journal Article
Chadborn, N. H., Devi, R., Williams, C., Sartain, K., Goodman, C., & Gordon, A. L. (2021). GPs’ involvement to improve care quality in care homes in the UK: a realist review. Health Services and Delivery Research, 9(20), 1-76. https://doi.org/10.3310/hsdr09200

Background
Organising health-care services for residents living in care homes is an important area of development in the UK and elsewhere. Medical care is provided by general practitioners in the UK, and the unique arrangement of the NHS means that... Read More about GPs’ involvement to improve care quality in care homes in the UK: a realist review.

Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections (2021)
Journal Article
Bath, P. M., Coleman, C. M., Gordon, A. L., Lim, W. S., & Webb, A. J. (2021). Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections. F1000Research, 10, 1-39. https://doi.org/10.12688/f1000research.51270.2

Although the antimicrobial potential of nitric oxide (NO) is widely published, it is little used clinically. NO is a key signalling molecule modulating vascular, neuronal, inflammatory and immune responses. Endogenous antimicrobial activity is largel... Read More about Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections.

Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations] (2021)
Journal Article
Bath, P. M., Coleman, C. M., Gordon, A. L., Lim, W. S., & Webb, A. J. (2021). Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations]. F1000Research, 10, 1-34. https://doi.org/10.12688/f1000research.51270.1

Although the antimicrobial potential of nitric oxide (NO) is widely published, it is little used clinically. NO is a key signalling molecule modulating vascular, neuronal, inflammatory and immune responses. Endogenous antimicrobial activity is largel... Read More about Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations].

Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals (2021)
Journal Article
Schlögl, M., Singler, K., Martinez-Velilla, N., Jan, S., Bischoff-Ferrari, H. A., Roller-Wirnsberger, R. E., …Gordon, A. L. (2021). Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals. European Geriatric Medicine, 12(6), 1181-1190. https://doi.org/10.1007/s41999-021-00532-1

Purpose
The aims of this study were to describe communication experiences while wearing a mask during COVID-19 pandemic in 2020, in order to identify possible mask-related barriers to COVID-19-adapted communications and to investigate whether the AB... Read More about Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals.

Research into ageing and frailty (2021)
Journal Article
Gordon, A. L., Witham, M. D., Henderson, E. J., Harwood, R. H., & Masud, T. (2021). Research into ageing and frailty. Future Healthcare Journal, 8(2), e237-e242. https://doi.org/10.7861/fhj.2021-0088

Research into ageing covers opportunities and challenges posed by an older population, and research to understand the ageing processes across the lifespan. The evidence base for Comprehensive Geriatric Assessment (CGA) is well established and efforts... Read More about Research into ageing and frailty.