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Feasibility and Biological Activity of a Ketogenic/Intermittent-Fasting Diet in Patients With Glioma (2021)
Journal Article
Schreck, K. C., Hsu, F.-C., Berrington, A., Henry-Barron, B., Vizthum, D., Blair, L., …Strowd, R. E. (2021). Feasibility and Biological Activity of a Ketogenic/Intermittent-Fasting Diet in Patients With Glioma. Neurology, 97(9), e953-e963. https://doi.org/10.1212/wnl.0000000000012386

OBJECTIVE: To examine the feasibility, safety, systemic biological activity, and cerebral activity of a ketogenic dietary intervention in patients with glioma.

METHODS: 25 patients with biopsy-confirmed WHO Grade 2-4 astrocytoma with stable diseas... Read More about Feasibility and Biological Activity of a Ketogenic/Intermittent-Fasting Diet in Patients With Glioma.

Estimation and removal of spurious echo artifacts in single‐voxel MRS using sensitivity encoding (2021)
Journal Article
Berrington, A., Považan, M., & Barker, P. B. (2021). Estimation and removal of spurious echo artifacts in single‐voxel MRS using sensitivity encoding. Magnetic Resonance in Medicine, 86(5), 2339-2352. https://doi.org/10.1002/mrm.28848

Purpose

In localized MRS, spurious echo artifacts commonly occur when unsuppressed signal outside the volume of interest is excited and refocused. In the spectral domain, these signals often overlap with metabolite resonances and hinder accurate q... Read More about Estimation and removal of spurious echo artifacts in single‐voxel MRS using sensitivity encoding.

Calibration-free regional RF shims for MRS (2021)
Journal Article
Berrington, A., Považan, M., Mirfin, C., Bawden, S., Park, Y. W., Marsh, D. C., …Gowland, P. A. (2021). Calibration-free regional RF shims for MRS. Magnetic Resonance in Medicine, 86(2), 611-624. https://doi.org/10.1002/mrm.28749

Purpose: Achieving a desired RF transmit field (B1+) in small regions-of-interest (ROIs) is critical for single-voxel MR spectroscopy at ultra-high field. RF shimming, using parallel transmission, requires B1+ mapping and optimisation, which limits i... Read More about Calibration-free regional RF shims for MRS.

DDRE-31. Feasibility and Biologic Activity of a Ketogenic / Intermittent Fasting Diet in Glioma Patients (2021)
Journal Article
Schreck, K., Hsu, F.-C., Berrington, A., Henry-Barron, B., Vizthum, D., Blair, L., …Strowd, R. (2021). DDRE-31. Feasibility and Biologic Activity of a Ketogenic / Intermittent Fasting Diet in Glioma Patients. Neuro-Oncology Advances, 3(Supplement_1), i13-i13. https://doi.org/10.1093/noajnl/vdab024.053

BACKGROUND
There has been increasing interest in exploring ketogenic diet therapies (KDT) in patients with glioma given the poor prognosis. The purpose of this single-arm, open label phase 2 study was to rigorously examine the feasibility, safety, s... Read More about DDRE-31. Feasibility and Biologic Activity of a Ketogenic / Intermittent Fasting Diet in Glioma Patients.