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Clinical and cost effectiveness of issuing longer versus shorter duration (3 month vs. 28 day) prescriptions in patients with chronic conditions: systematic review and economic modelling

Miani, Céline; Martin, Adam; Exley, Josephine; Doble, Brett; Wilson, Ed; Payne, Rupert; Avery, Anthony; Meads, Catherine; Kirtley, Anne; Morgan Jones, Molly; King, Sarah

Authors

Céline Miani

Adam Martin

Josephine Exley

Brett Doble

Ed Wilson

Rupert Payne

Anthony Avery

Catherine Meads

Anne Kirtley

Molly Morgan Jones

Sarah King



Abstract

Background: To reduce expenditure on, and wastage of, drugs, some commissioners have encouraged general practitioners to issue shorter prescriptions, typically 28 days in length; however, the evidence base for this recommendation is uncertain.
Objective: To evaluate the evidence of the clinical effectiveness and cost-effectiveness of shorter versus longer prescriptions for people with stable chronic conditions treated in primary care.
Design/data sources: The design of the study comprised three elements. First, a systematic review comparing 28-day prescriptions with longer prescriptions in patients with chronic conditions treated in primary care, evaluating any relevant clinical outcomes, adherence to treatment, costs and cost-effectiveness. Databases searched included MEDLINE (PubMed), EMBASE, Cumulative Index to Nursing and Allied Health Literature, Web of Science and Cochrane Central Register of Controlled Trials. Searches were from database inception to October 2015 (updated search to June 2016 in PubMed). Second, a cost analysis of medication wastage associated with

Journal Article Type Article
Publication Date Dec 21, 2017
Journal Health Technology Assessment
Print ISSN 1366-5278
Electronic ISSN 1366-5278
Publisher NIHR Journals Library
Peer Reviewed Peer Reviewed
Volume 21
Issue 78
APA6 Citation Miani, C., Martin, A., Exley, J., Doble, B., Wilson, E., Payne, R., …King, S. (2017). Clinical and cost effectiveness of issuing longer versus shorter duration (3 month vs. 28 day) prescriptions in patients with chronic conditions: systematic review and economic modelling. Health Technology Assessment, 21(78), doi:10.3310/hta21780
DOI https://doi.org/10.3310/hta21780
Publisher URL https://www.journalslibrary.nihr.ac.uk/hta/hta21780/#/abstract
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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