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Catalytic reductive N-alkylation of amines using carboxylic acids

Andrews, Keith Gordon; Summers, Declan; Donnelly, Liam; Denton, Ross Matthew

Authors

Keith Gordon Andrews

Declan Summers

Liam Donnelly

ROSS DENTON ross.denton@nottingham.ac.uk
Professor of Organic Chemistry



Abstract

We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids. The two-phase process involves silane mediated direct amidation followed by catalytic reduction.

Citation

Andrews, K. G., Summers, D., Donnelly, L., & Denton, R. M. (2015). Catalytic reductive N-alkylation of amines using carboxylic acids. Chemical Communications, doi:10.1039/C5CC08881J

Journal Article Type Article
Acceptance Date Dec 3, 2015
Publication Date Dec 3, 2015
Deposit Date Dec 14, 2015
Publicly Available Date Dec 14, 2015
Journal Chemical Communications
Print ISSN 1359-7345
Electronic ISSN 1364-548X
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
DOI https://doi.org/10.1039/C5CC08881J
Public URL http://eprints.nottingham.ac.uk/id/eprint/31067
Publisher URL http://pubs.rsc.org/en/content/articlelanding/2015/cc/c5cc08881j#!divAbstract
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf

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Denton paper for Nottingham ePrints.pdf (815 Kb)
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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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