Catalytic reductive N-alkylation of amines using carboxylic acids

Andrews, Keith Gordon; Summers, Declan; Donnelly, Liam; Denton, Ross Matthew

Abstract

We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids. The two-phase process involves silane mediated direct amidation followed by catalytic reduction.

Citation

Andrews, K. G., Summers, D., Donnelly, L., & Denton, R. M. (2015). Catalytic reductive N-alkylation of amines using carboxylic acids. Chemical Communications, https://doi.org/10.1039/C5CC08881J

• Journal Article Type: Article
• Acceptance Date: Dec 3, 2015
• Publication Date: Dec 3, 2015
• Deposit Date: Dec 14, 2015
• Publicly Available Date: Dec 14, 2015
• Journal: Chemical Communications
• Print ISSN: 1359-7345
• Electronic ISSN: 1364-548X
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1039/C5CC08881J
• Public URL: https://nottingham-repository.worktribe.com/output/770268
• Publisher URL: http://pubs.rsc.org/en/content/articlelanding/2015/cc/c5cc08881j#!divAbstract