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Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration

Poser, Stephen W.; Androutsellis-Theotokis, Andreas

Authors

Stephen W. Poser

Andreas Androutsellis-Theotokis



Abstract

There is a growing interest in the therapeutic utility of compounds derived from Curcuma longa, an herb of the Zingiberaceae family that has been part of traditional medicine for centuries. Recent reports suggest that bioactive compounds isolated from the rhizome of these plants can address two key aspects of brain injury following stroke that must be dealt with for functional recovery to occur: the moderation of neuroinflammation, and the mobilization of endogenous stem cells resident in the nervous system. Defining their mechanism of action remains a question, but emerging evidence may point towards one shared with more classic modulators of neural stem cell proliferation and survival.

Journal Article Type Article
Publication Date Nov 17, 2014
Journal Stem Cell Research & Therapy
Print ISSN 0012-1797
Electronic ISSN 1939-327X
Publisher American Diabetes Association
Peer Reviewed Peer Reviewed
Volume 5
Issue 6
APA6 Citation Poser, S. W., & Androutsellis-Theotokis, A. (2014). Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration. Diabetes, 5(6), https://doi.org/10.1186/scrt517
DOI https://doi.org/10.1186/scrt517
Publisher URL http://stemcellres.biomedcentral.com/articles/10.1186/scrt517
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0





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