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Hypoglycaemia in type 2 diabetes treated with pre-mixed insulin

Idris, Iskandar; Annamalai, Narayan; Aung, Theingi; Binnian, Ian; Gibb, Fraser W; Malik, Mohammed Iqbal Afzal; Ramtoola, Shenaz

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Authors

ISKANDAR IDRIS Iskandar.Idris@nottingham.ac.uk
Professor of Diabetes and Metabolic Medicine

Narayan Annamalai

Theingi Aung

Ian Binnian

Fraser W Gibb

Mohammed Iqbal Afzal Malik

Shenaz Ramtoola



Abstract

The burden of hypoglycaemia in type 2 diabetes is increasingly recognised, regardless of treatment regimen.1-3 However, time in hypoglycaemia for individuals with type 2 diabetes who use pre-mixed (biphasic) insulin remains unclear. The aim of our prospective, open-label, single arm, pilot, observational study was to determine the amount of time individuals in this cohort spent in hypoglycaemia (ISRCTN 10603608). The primary endpoint was sensor derived time in hypoglycaemia (TBR,

Citation

Idris, I., Annamalai, N., Aung, T., Binnian, I., Gibb, F. W., Malik, M. I. A., & Ramtoola, S. (2022). Hypoglycaemia in type 2 diabetes treated with pre-mixed insulin. Diabetic Medicine, 39(2), Article e14684. https://doi.org/10.1111/dme.14684

Journal Article Type Letter
Acceptance Date Aug 30, 2021
Online Publication Date Aug 31, 2021
Publication Date Feb 1, 2022
Deposit Date Sep 9, 2021
Publicly Available Date Sep 1, 2022
Journal Diabetic Medicine
Print ISSN 0742-3071
Electronic ISSN 1464-5491
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 39
Issue 2
Article Number e14684
DOI https://doi.org/10.1111/dme.14684
Keywords Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine
Public URL https://nottingham-repository.worktribe.com/output/6189389
Publisher URL https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.14684
Additional Information This is the pre-peer reviewed version of the following article: Idris, I., Annamalai, N., Aung, T., Binnian, I., Gibb, F.W., Malik, M.I.A. and Ramtoola, S. (2021), Letter: Hypoglycaemia in type 2 diabetes treated with pre-mixed insulin. Diabetic Medicine. Accepted Author Manuscript e14684, which has been published in final form at https://doi.org/10.1111/dme.14684. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.

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