Justin Claude Kemmegne-Mbouguen
Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode
Kemmegne-Mbouguen, Justin Claude; Tchoumi, Firmin Parfait; Mouafo-Tchinda, Edwige; Langmi, Henrietta W.; Bambalaza, Sonwabo E.; Musyoka, Nicholas M.; Kowenje, Chrispin; Mokaya, Robert
Authors
Firmin Parfait Tchoumi
Edwige Mouafo-Tchinda
Henrietta W. Langmi
Sonwabo E. Bambalaza
Nicholas M. Musyoka
Chrispin Kowenje
Robert Mokaya
Abstract
© The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. A graphene foam/zirconium-based metal-organic framework composite (GF/UiO-66) was synthesised and then employed to modify glassy carbon electrodes (GCE). These modified electrodes were successfully used for the simultaneous detection and determination of acetaminophen (AC) and tryptophan (TRYP). The combination of GF and UiO-66 endowed the electrodes with a large surface area, good biological compatibility and stability as well as high selectivity and sensitivity. The linear calibration plots for AC and TRYP were obtained over the range of 0.5-200 μM (R2 = 0.999) and 0.5-113 μM (R2 = 0.999) with detection limits of 0.07 μM and 0.06 μM, respectively. The modified electrodes were successfully applied for the determination of AC and TRYP in a pharmaceutical preparation and urine, respectively.
Citation
Kemmegne-Mbouguen, J. C., Tchoumi, F. P., Mouafo-Tchinda, E., Langmi, H. W., Bambalaza, S. E., Musyoka, N. M., …Mokaya, R. (2020). Simultaneous quantification of acetaminophen and tryptophan using a composite graphene foam/Zr-MOF film modified electrode. New Journal of Chemistry, 44(30), 13108-13117. https://doi.org/10.1039/d0nj02374d
Journal Article Type | Article |
---|---|
Acceptance Date | Jul 13, 2020 |
Online Publication Date | Jul 13, 2020 |
Publication Date | Jul 13, 2020 |
Deposit Date | Jul 24, 2020 |
Publicly Available Date | Jul 14, 2021 |
Journal | New Journal of Chemistry |
Print ISSN | 1144-0546 |
Electronic ISSN | 1369-9261 |
Publisher | Royal Society of Chemistry |
Peer Reviewed | Peer Reviewed |
Volume | 44 |
Issue | 30 |
Pages | 13108-13117 |
DOI | https://doi.org/10.1039/d0nj02374d |
Keywords | Materials Chemistry; General Chemistry; Catalysis |
Public URL | https://nottingham-repository.worktribe.com/output/4784548 |
Publisher URL | https://pubs.rsc.org/en/content/articlelanding/2020/NJ/D0NJ02374D#!divAbstract |
Additional Information | : This document is Similarity Check deposited; : Supplementary Information; : Justin Claude Kemmegne-Mbouguen (ORCID); : Henrietta W. Langmi (ORCID); : Nicholas M. Musyoka (ORCID); : Nicholas M. Musyoka (ResearcherID); : Robert Mokaya (ORCID); : Single-blind; : Received 11 May 2020; Accepted 13 July 2020; Accepted Manuscript published 13 July 2020; Advance Article published 20 July 2020 |
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