Presence of Vascular Invasion in Colorectal Cancer Correlates with TNM8 Nodal Status Classification

Fadhil, W; Ilyas, M; Mukherjee, A

Abstract

Purpose of the study: Vascular invasion (VI) is an important prognostic marker in several malignancies including colorectal cancer (CRC). The correlation between the VI status and the revised nodal stage of CRC as per TNM8, was investigated in this study.
Methods: 1000 consecutive cases of CRC from a tertiary centre, diagnosed between 2008-2014 were investigated for VI profiles from histopathological reports on IT records and results correlated to clinicopathological variables including the revised nodal stage as defined by the TNM8 classification.
Summary of results: 483 of 985 (49%) cases showed extramural vascular invasion (EMVI), the incidence of which within stages 1-4 of CRC was 1%, 44%, 68%, 72% respectively (p

• Conference Name: Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 2–4 July 2019
• Conference Location: Harrogate, UK
• Start Date: Jul 2, 2019
• End Date: Jul 4, 2019
• Acceptance Date: Apr 24, 2019
• Online Publication Date: Sep 16, 2019
• Publication Date: Sep 16, 2019
• Deposit Date: Nov 14, 2019
• Publicly Available Date: Feb 16, 2021
• Publisher: Wiley
• Volume: 249
• Pages: S41
• Series Title: Supplement: Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 2–4 July 2019
• Series ISSN: 1096-9896
• Book Title: Leeds Pathology 2019 Supplement: 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 2–4 July 2019
• DOI: https://doi.org/10.1002/path.5345
• Public URL: https://nottingham-repository.worktribe.com/output/3279582
• Publisher URL: https://onlinelibrary.wiley.com/doi/10.1002/path.5345