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Defining patterns of care in the management of patients with brain metastases in a large oncology centre: A single?centre retrospective audit of 236 cases

Aznar?Garcia, Luis; O�Cathail, Micheal; Bentley, Rebecca; O'Cathail, Michael; Aznar-Garcia, Luis; Crosby, Vincent; Wilcock, Andrew; Christian, Judith

Authors

Luis Aznar?Garcia

Micheal O�Cathail

Rebecca Bentley

Michael O'Cathail

Luis Aznar-Garcia

Vincent Crosby

Andrew Wilcock

Judith Christian



Abstract

Aims: The role of selected treatments for brain metastases (BM) is well documented; however the prevalence of these is not. We report on the patterns of care in the management of BM in a large Oncology centre.

Materials and methods: We retrospectively audited 236 cases of newly diagnosed BM from January 2016 to December 2017 by looking at 2 years of radiology reports and gathered data on primary site, survival, treatment received, palliative care input and brain metastases related admissions.

Results Eighty-two percent of cases were related to lung, breast and melanoma primaries. Half of patients received a form of treatment with the other half receiving best supportive care. Of these, whole brain radiotherapy (39%) and stereotactic radiosurgery (40%) were the most common treatment modalities. Most common reasons for admissions were headaches, seizures, weakness and confusion.

Conclusion: This is the first study in the UK that gives an in-depth overview of the real world management of brain metastases. We have demonstrated the prevalence of treatment across the spectrum of brain metastases patients. Radiotherapy is the mainstay of treatment in nearly 80% of cases; however care needs to be taken in ensuring that SRS is offered to those who are suitable.

Citation

Aznar‐Garcia, L., O’Cathail, M., Bentley, R., O'Cathail, M., Aznar-Garcia, L., Crosby, V., …Christian, J. (2019). Defining patterns of care in the management of patients with brain metastases in a large oncology centre: A single‐centre retrospective audit of 236 cases. European Journal of Cancer Care, 28(4), 1-7. https://doi.org/10.1111/ecc.13059

Journal Article Type Article
Acceptance Date Apr 3, 2019
Online Publication Date Apr 16, 2019
Publication Date Jul 1, 2019
Deposit Date Apr 17, 2019
Publicly Available Date Mar 28, 2024
Journal European Journal of Cancer Care
Print ISSN 0961-5423
Electronic ISSN 1365-2354
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 28
Issue 4
Article Number e13059
Pages 1-7
DOI https://doi.org/10.1111/ecc.13059
Public URL https://nottingham-repository.worktribe.com/output/1818368
Publisher URL https://onlinelibrary.wiley.com/doi/abs/10.1111/ecc.13059?af=R
Additional Information This is the peer reviewed version of the following article: Bentley, R, O’Cathail, M, Aznar‐Garcia, L, Crosby, V, Wilcock, A, Christian, J. Defining patterns of care in the management of patients with brain metastases in a large oncology centre: A single‐centre retrospective audit of 236 cases. Eur J Cancer Care. 2019, which has been published in final form at https://doi.org/10.1111/ecc.13059
. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.