Outputs (165)

An experimental and theoretical study of the valence shell photoelectron spectra of 2-chloropyridine and 3-chloropyridine (2017)
Journal Article
Holland, D., Powis, I., Trofimov, A., Menzies, R., Potts, A., Karlsson, L., …Schirmer, J. (in press). An experimental and theoretical study of the valence shell photoelectron spectra of 2-chloropyridine and 3-chloropyridine. Journal of Chemical Physics, https://doi.org/10.1063/1.4999433

The valence shell photoelectron spectra of 2-chloropyridine and 3-chloropyridine have been studied both experimentally and theoretically. Synchrotron radiation has been employed to record angle resolved photoelectron spectra in the photon energy rang... Read More about An experimental and theoretical study of the valence shell photoelectron spectra of 2-chloropyridine and 3-chloropyridine.

Engineered, highly reactive substrates of microbial transglutaminase enable protein labeling within various secondary structure elements: Engineered, Highly Reactive Substrates of Microbial Transglutaminase (2017)
Journal Article
Rachel, N. M., Quaglia, D., Lévesque, É., Charette, A. B., & Pelletier, J. N. (2017). Engineered, highly reactive substrates of microbial transglutaminase enable protein labeling within various secondary structure elements: Engineered, Highly Reactive Substrates of Microbial Transglutaminase. Protein Science, 26(11), 2268-2279. https://doi.org/10.1002/pro.3286

Microbial transglutaminase (MTG) is a practical tool to enzymatically form isopeptide bonds between peptide or protein substrates. This natural approach to crosslinking the side‐chains of reactive glutamine and lysine residues is solidly rooted in fo... Read More about Engineered, highly reactive substrates of microbial transglutaminase enable protein labeling within various secondary structure elements: Engineered, Highly Reactive Substrates of Microbial Transglutaminase.

Cigarette butt-derived carbons have ultra-high surface area and unprecedented hydrogen storage capacity (2017)
Journal Article
Blankenship, T. S., & Mokaya, R. (in press). Cigarette butt-derived carbons have ultra-high surface area and unprecedented hydrogen storage capacity. Energy and Environmental Science, https://doi.org/10.1039/C7EE02616A

Discarded cigarette filters, in the form of cigarette butts, are a major waste disposal and environmental pollution hazard due to mainly containing cellulose acetate which is nonbiodegradable; 5.8 trillion cigarettes are smoked worldwide per annum ge... Read More about Cigarette butt-derived carbons have ultra-high surface area and unprecedented hydrogen storage capacity.

Consistent assignment of the vibrations of symmetric and asymmetric ortho-disubstituted benzenes (2017)
Journal Article
Tuttle, W. D., Gardner, A. M., Andrejeva, A., Kemp, D., Wakefield, J. C., & Wright, T. G. (in press). Consistent assignment of the vibrations of symmetric and asymmetric ortho-disubstituted benzenes. Journal of Molecular Spectroscopy, 344, https://doi.org/10.1016/j.jms.2017.10.011

The form of molecular vibrations, and changes in these, give valuable insights into geometric and electronic structure upon electronic excitation or ionization, and within families of molecules. Here, we give a description of the phenyl-ring-localize... Read More about Consistent assignment of the vibrations of symmetric and asymmetric ortho-disubstituted benzenes.

Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein (2017)
Journal Article
Manzi, L., Barrow, A. S., Hopper, J. T., Kaminska, R., Kleanthous, C., Robinson, C. V., …Oldham, N. J. (2017). Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein. Angewandte Chemie International Edition, 56(47), 14873-14877. https://doi.org/10.1002/anie.201708254

© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Mapping the interaction sites between membrane-spanning proteins is a key challenge in structural biology. In this study a carbene-footprinting approach was developed and applied to identify the in... Read More about Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein.

Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates (2017)
Journal Article
Simmons, T. J., Frandsen, K. E. H., Ciano, L., Tryfona, T., Lenfant, N., Poulsen, J. C., …Dupree, P. (2017). Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates. Nature Communications, 8(1), Article 1064. https://doi.org/10.1038/s41467-017-01247-3

Lytic polysaccharide monooxygenases (LPMOs) are industrially important copper-dependent enzymes that oxidatively cleave polysaccharides. Here we present a functional and structural characterization of two closely related AA9-family LPMOs from Lentinu... Read More about Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates.

Thiol-Stabilized Gold Nanoparticles: New Ways To Displace Thiol Layers Using Yttrium or Lanthanide Chlorides (2017)
Journal Article
Vanegas, J. P., Scaiano, J. C., & Lanterna, A. E. (2017). Thiol-Stabilized Gold Nanoparticles: New Ways To Displace Thiol Layers Using Yttrium or Lanthanide Chlorides. Langmuir, 33(43), 12149-12154. https://doi.org/10.1021/acs.langmuir.7b01898

We use the aurophilic interactions shown by lanthanides to overcome the sulfur–gold interaction. UV–vis and X-ray photoelectron spectroscopy confirm that yttrium or lanthanide chlorides easily displace sulfur ligands from the surface of thiol-stabili... Read More about Thiol-Stabilized Gold Nanoparticles: New Ways To Displace Thiol Layers Using Yttrium or Lanthanide Chlorides.

Flow bioreactors as complementary tools for biocatalytic process intensification (2017)
Journal Article
Tamborini, L., Fernandes, P., Paradisi, F., & Molinari, F. (in press). Flow bioreactors as complementary tools for biocatalytic process intensification. Trends in Biotechnology, https://doi.org/10.1016/j.tibtech.2017.09.005

Biocatalysis has widened its scope and relevance since new molecular tools, including improved expression systems for proteins, protein and metabolic engineering, and rational techniques for immobilization, have become available. However, application... Read More about Flow bioreactors as complementary tools for biocatalytic process intensification.

Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis (2017)
Journal Article
Shaw, D., Hill, R., Simpson, N., Husseini, F., Robb, K., Greetham, G. M., …Hunt, N. (in press). Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis. Chemical Science, 8, https://doi.org/10.1039/C7SC03336B

Antimicrobial resistance represents a growing global health problem. The emergence of novel resistance mechanisms necessitates the development of alternative approaches to investigate the molecular fundamentals of resistance, leading ultimately to ne... Read More about Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis.

Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols (2017)
Journal Article
Alsafadi, D., Alsalman, S., & Paradisi, F. (in press). Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols. Organic and Biomolecular Chemistry, https://doi.org/10.1039/C7OB02299A

Enzymatic synthesis of enantiopure aromatic secondary alcohols (including substituted, heteroaromatic and bicyclic structures) were carried out using the halophilic alcohol dehydrogenase ADH2 from Haloferax volcanii (HvADH2). This enzyme showed an un... Read More about Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols.