Outputs (151)

Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines (2016)
Journal Article
Smith, J. J., Best, D., & Lam, H. W. (2016). Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines. Chemical Communications, https://doi.org/10.1039/C6CC00603E

Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.

Synthesis of triazole-linked morpholino oligonucleotides via Cu1 catalysed cycloaddition (2016)
Journal Article
Palframan, M. J., Alharthy, R. D., Powalowska, P. K., & Hayes, C. J. (in press). Synthesis of triazole-linked morpholino oligonucleotides via Cu1 catalysed cycloaddition. Organic and Biomolecular Chemistry, 14, https://doi.org/10.1039/C6OB00007J

Triazole-linked morpholino (TLMO) oligonucleic acids were synthesised using the CuI catalysed (3 + 2) azide–alkyne cycloaddition (CuAAC) reaction. The modified DNA analogues were incorporated into 13-mer sequences via solid phase synthesis. UV meltin... Read More about Synthesis of triazole-linked morpholino oligonucleotides via Cu1 catalysed cycloaddition.

Synthesis of quaternary aryl phosphonium salts: photoredox-mediated phosphine arylation (2016)
Journal Article
Fearnley, A., An, J., Jackson, M., Lindovska, P., & Denton, R. (2016). Synthesis of quaternary aryl phosphonium salts: photoredox-mediated phosphine arylation. Chemical Communications, 52, https://doi.org/10.1039/C6CC00556J

We report a synthesis method for the construction of quaternary aryl phoshonium salts at ambient temperature. The regiospecific reaction invovles the coupling of phosphines with aryl radicals derived from diaryliodonium salts under photoredox conditi... Read More about Synthesis of quaternary aryl phosphonium salts: photoredox-mediated phosphine arylation.

PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells (2016)
Journal Article
Rogers, S., Fey, D., McCloy, R. A., Parker, B. L., Mitchell, N. J., Payne, R. J., …Burgess, A. (2016). PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells. Journal of Cell Science, 129(7), 1340-1354. https://doi.org/10.1242/jcs.179754

Entry into mitosis is driven by the phosphorylation of thousands of substrates, under the master control of Cdk1. During entry into mitosis, Cdk1, in collaboration with MASTL kinase, represses the activity of the major mitotic protein phosphatases, P... Read More about PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells.

A sensing mechanism for the detection of carbon nanotubes using selective photoluminescent probes based on ionic complexes with organic dyes (2016)
Journal Article
Lutsyk, P., Arif, R., Hruby, J., Bukivskyi, A., Vinijchuk, O., Shandura, M., …Rozhin, A. (2016). A sensing mechanism for the detection of carbon nanotubes using selective photoluminescent probes based on ionic complexes with organic dyes. Light: Science and Applications, 5, Article e16028. https://doi.org/10.1038/lsa.2016.28

© 2016 CIOMP. All rights reserved. The multifunctional properties of carbon nanotubes (CNTs) make them a powerful platform for unprecedented innovations in a variety of practical applications. As a result of the surging growth of nanotechnology, nano... Read More about A sensing mechanism for the detection of carbon nanotubes using selective photoluminescent probes based on ionic complexes with organic dyes.

A Breathing Zirconium Metal-Organic Framework with Reversible Loss of Crystallinity by Correlated Nanodomain Formation (2016)
Journal Article
Bueken, B., Vermoortele, F., Cliffe, M. J., Wharmby, M. T., Foucher, D., Wieme, J., …De Vos, D. (2016). A Breathing Zirconium Metal-Organic Framework with Reversible Loss of Crystallinity by Correlated Nanodomain Formation. Chemistry - A European Journal, 22(10), 3264-3267. https://doi.org/10.1002/chem.201600330

The isoreticular analogue of the metal–organic framework UiO‐66(Zr), synthesized with the flexible trans‐1,4‐cyclohexanedicarboxylic acid as linker, shows a peculiar breathing behavior by reversibly losing long‐range crystalline order upon evacuation... Read More about A Breathing Zirconium Metal-Organic Framework with Reversible Loss of Crystallinity by Correlated Nanodomain Formation.

Understanding anionic Chugaev elimination in pericyclic tetracene formation (2016)
Journal Article
Burroughs, L., Ritchie, J., & Woodward, S. (2016). Understanding anionic Chugaev elimination in pericyclic tetracene formation. Tetrahedron, 72(13), https://doi.org/10.1016/j.tet.2016.02.025

The reaction pathway for the formation of tetracenes from the diols 1,2-C6H4(CHOHC≡CAr)2 , LiHDMS, CS2 and MeI has been modelled by computational methods at the CBS-QB3 level of theory. Comparison of PhCHOC(=S)YCCPh (Y = S- or SMe) indicates a sligh... Read More about Understanding anionic Chugaev elimination in pericyclic tetracene formation.

Mechanisms of monovacancy diffusion in graphene (2016)
Journal Article
Wadey, J. D., Markevich, A., Robertson, A., Warner, J., Kirkland, A., & Besley, E. (2016). Mechanisms of monovacancy diffusion in graphene. Chemical Physics Letters, 648, 161-165. https://doi.org/10.1016/j.cplett.2016.02.005

A comprehensive investigation of monovacancy diffusion in graphene has been carried out with the use of density functional theory and the climbing image nudged elastic band method. An out-of-plane spiro structure is found for the first-order saddle p... Read More about Mechanisms of monovacancy diffusion in graphene.

Consistent assignment of the vibrations of symmetric and asymmetric para-disubstituted benzene molecules (2016)
Journal Article
Andrejeva, A., Gardner, A. M., Tuttle, W. D., & Wright, T. G. (2016). Consistent assignment of the vibrations of symmetric and asymmetric para-disubstituted benzene molecules. Journal of Molecular Spectroscopy, https://doi.org/10.1016/j.jms.2016.02.004

We give a description of the phenyl-ring-localized vibrational modes of the ground states of the para-disubstituted benzene molecules including both symmetric and asymmetric cases. In line with others, we quickly conclude that the use of Wilson mode... Read More about Consistent assignment of the vibrations of symmetric and asymmetric para-disubstituted benzene molecules.

Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N−H Insertion Reaction of Metallocarbenes with β-Aminoketone Derivatives (2016)
Journal Article
Nicolle, S. M., Lewis, W., Hayes, C. J., & Moody, C. J. (2016). Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N−H Insertion Reaction of Metallocarbenes with β-Aminoketone Derivatives. Angewandte Chemie International Edition, 55(11), 3749-3753. https://doi.org/10.1002/anie.201511433

A highly stereoselective route to functionalized pyrrolidines from the metal catalyzed diverted N-H insertion of a range of diazocarbonyl compounds with β-aminoketone derivatives is described. A number of catalysts (rhodium(II) carboxylate dimers, co... Read More about Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N−H Insertion Reaction of Metallocarbenes with β-Aminoketone Derivatives.