Outputs (156)

Neuropsychological outcomes of children with Optic Pathway Glioma (2020)
Journal Article
Papini, C., Dineen, R. A., Walker, D. A., Thomas, S., & Pitchford, N. J. (2020). Neuropsychological outcomes of children with Optic Pathway Glioma. Scientific Reports, 10(1), Article 3344. https://doi.org/10.1038/s41598-020-59896-2

Optic Pathway Glioma (OPG) is a relatively common brain tumour in childhood; however, there is scarce understanding of neuropsychological sequelae in these survivors. In this study, 12 children with diagnosis of OPG before 6 years of age received a c... Read More about Neuropsychological outcomes of children with Optic Pathway Glioma.

Calcium buffers and L-type calcium channels as modulators of cardiac subcellular alternans (2020)
Journal Article
Lai, Y. M., Coombes, S., & Thul, R. (2020). Calcium buffers and L-type calcium channels as modulators of cardiac subcellular alternans. Communications in Nonlinear Science and Numerical Simulation, 85, Article 105181. https://doi.org/10.1016/j.cnsns.2020.105181

In cardiac myocytes, calcium cycling links the dynamics of the membrane potential to the activation of the contractile filaments. Perturbations of the calcium signalling toolkit have been demonstrated to disrupt this connection and lead to numerous p... Read More about Calcium buffers and L-type calcium channels as modulators of cardiac subcellular alternans.

Graph Theoretic Analysis of Brain Connectomics in Multiple Sclerosis: Reliability and Relationship to Cognition (2020)
Journal Article
Welton, T., Constantinescu, C. S., Auer, D. P., & Dineen, R. A. (2020). Graph Theoretic Analysis of Brain Connectomics in Multiple Sclerosis: Reliability and Relationship to Cognition. Brain Connectivity, 10(2), 95-104. https://doi.org/10.1089/brain.2019.0717

Research suggests that disruption of brain networks might explain cognitive deficits in multiple sclerosis (MS). The reliability and effectiveness of graph-theoretic network metrics as measures of cognitive performance were tested in 37 people with M... Read More about Graph Theoretic Analysis of Brain Connectomics in Multiple Sclerosis: Reliability and Relationship to Cognition.

Face and content validity analysis of the Speech, Spatial and Qualities of Hearing Scale for Parents (SSQ-P) when used in a clinical service without interviews or week-long observation periods (2020)
Journal Article
Killan, C. F., Baxter, P. D., & Killan, E. C. (2020). Face and content validity analysis of the Speech, Spatial and Qualities of Hearing Scale for Parents (SSQ-P) when used in a clinical service without interviews or week-long observation periods. International Journal of Pediatric Otorhinolaryngology, 133, Article 109964. https://doi.org/10.1016/j.ijporl.2020.109964

Objectives
To assess the face and content validity of the Speech, Spatial and Qualities of Hearing Scale for Parents (SSQ-P) when used in a clinical setting without the recommended interviews and observation periods.

Methods
SSQ-P responses comp... Read More about Face and content validity analysis of the Speech, Spatial and Qualities of Hearing Scale for Parents (SSQ-P) when used in a clinical service without interviews or week-long observation periods.

Does the magnetization transfer effect bias chemical exchange saturation transfer effects? Quantifying chemical exchange saturation transfer in the presence of magnetization transfer (2020)
Journal Article
Smith, A. K., Ray, K. J., Larkin, J. R., Craig, M., Smith, S. A., & Chappell, M. A. (2020). Does the magnetization transfer effect bias chemical exchange saturation transfer effects? Quantifying chemical exchange saturation transfer in the presence of magnetization transfer. Magnetic Resonance in Medicine, 84(3), 1359-1375. https://doi.org/10.1002/mrm.28212

Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI (2020)
Journal Article
Iwabuchi, S. J., Xing, Y., Cottam, W. J., Drabek, M. M., Tadjibaev, A., Fernandes, G. S., …Auer, D. P. (2020). Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI. PAIN, 161(6), 1255-1263. https://doi.org/10.1097/j.pain.0000000000001829

Chronic musculoskeletal pain is a common problem globally. Current evidence suggests that maladapted central pain pathways are associated with pain chronicity, for example, in postoperative pain after knee replacement. Other factors such as low mood,... Read More about Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI.

Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2) (2020)
Journal Article
Muir, K. W., Bulters, D., Willmot, M., Sprigg, N., Dixit, A., Ward, N., …Sinden, J. (2020). Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2). Journal of Neurology, Neurosurgery and Psychiatry, 91(4), 396-401. https://doi.org/10.1136/jnnp-2019-322515

Background

Human neural stem cell implantation may offer improved recovery from stroke. We investigated the feasibility of intracerebral implantation of the allogeneic human neural stem cell line CTX0E03 in the subacute—chronic recovery phase of... Read More about Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2).

Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial (2020)
Journal Article
Macho, O., Borges, F. K., Bhandari, M., Guerra-Farfan, E., Patel, A., Sigamani, A., …Quintas, S. (2020). Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial. Lancet, 395(10225), 698-708. https://doi.org/10.1016/s0140-6736%2820%2930058-1

Hypercapnia augments resistive exercise‐induced elevations in intraocular pressure in older individuals (2020)
Journal Article
Mekjavic, I. B., Amoaku, W., Mlinar, T., & Mekjavic, P. J. (2020). Hypercapnia augments resistive exercise‐induced elevations in intraocular pressure in older individuals. Experimental Physiology, 105(4), 641-651. https://doi.org/10.1113/ep088236

The present study assessed the effect of 6° head down (establishing the cephalad displacement noted in astronauts in microgravity) prone (simulating the effect on the eye) tilt during rest and exercise (simulating exercise performed by astronauts to... Read More about Hypercapnia augments resistive exercise‐induced elevations in intraocular pressure in older individuals.

Age, sex, race and ethnicity representativeness of randomised controlled trials in peri‐operative medicine (2020)
Journal Article
Lindsay, W. A., Murphy, M. M., Almghairbi, D. S., & Moppett, I. K. (2020). Age, sex, race and ethnicity representativeness of randomised controlled trials in peri‐operative medicine. Anaesthesia, 75(6), 809-815. https://doi.org/10.1111/anae.14967

The applicability of the results of any clinical trial will depend to a large extent on whether the study population is representative of the population seen in clinical practice. The growing older surgical population presents challenges for peri-ope... Read More about Age, sex, race and ethnicity representativeness of randomised controlled trials in peri‐operative medicine.