Outputs (120)

Adaptive benefit of cross-modal plasticity following cochlear implantation in deaf adults (2017)
Journal Article
Anderson, C. A., Wiggins, I. M., Kitterick, P. T., & Hartley, D. E. H. (2017). Adaptive benefit of cross-modal plasticity following cochlear implantation in deaf adults. Proceedings of the National Academy of Sciences, 114(38), 10256-10261. https://doi.org/10.1073/pnas.1704785114

© 2017, National Academy of Sciences. All rights reserved. It has been suggested that visual language is maladaptive for hearing restoration with a cochlear implant (CI) due to cross-modal recruitment of auditory brain regions. Rehabilitative guideli... Read More about Adaptive benefit of cross-modal plasticity following cochlear implantation in deaf adults.

Automatic speech recognition predicts speech intelligibility and comprehension for listeners with simulated age-related hearing loss (2017)
Journal Article
Fontan, L., Ferrané, I., Farinas, J., Pinquier, J., Tardieu, J., Magnen, C., …Füllgrabe, C. (in press). Automatic speech recognition predicts speech intelligibility and comprehension for listeners with simulated age-related hearing loss. Journal of Speech, Language, and Hearing Research, https://doi.org/10.1044/2017_JSLHR-S-16-0269

Purpose: To assess speech processing for listeners with simulated age-related hearing loss (ARHL) and to investigate whether the observed performance can be replicated using an Automatic Speech Recognition (ASR) system. The long-term goal of this re... Read More about Automatic speech recognition predicts speech intelligibility and comprehension for listeners with simulated age-related hearing loss.

Situationally influenced tinnitus coping strategies: a mixed methods approach (2017)
Journal Article
Beukes, E. W., Manchaiah, V., Andersson, G., Allen, P. M., Terlizzi, P. M., & Baguley, D. M. (in press). Situationally influenced tinnitus coping strategies: a mixed methods approach. Disability and Rehabilitation, https://doi.org/10.1080/09638288.2017.1362708

Purpose: The primary aim of this study was to identify coping strategies used to manage problematic tinnitus situations. A secondary aim was to determine whether different approaches were related to the level of tinnitus distress, anxiety, depression... Read More about Situationally influenced tinnitus coping strategies: a mixed methods approach.

Validating and comparing stroke prognosis scales (2017)
Journal Article
Quinn, T. J., Singh, S., Lees, K. R., Bath, P. M., & Myint, P. K. (2017). Validating and comparing stroke prognosis scales. Neurology, 89(10), https://doi.org/10.1212/WNL.0000000000004332

Objective: To compare the prognostic accuracy of various acute stroke prognostic scales using a large, independent, clinical trials dataset.

Methods: We directly compared 8 stroke prognostic scales, chosen based on focused literature review (Acute... Read More about Validating and comparing stroke prognosis scales.

Homozygous resistance to thyroid hormone β: can combined antithyroid drug and triiodothyroacetic acid treatment prevent cardiac failure? (2017)
Journal Article
Moran, C., Habeb, A. M., Kahaly, G. J., Kampmann, C., Hughes, M., Marek, J., …Chatterjee, K. (2017). Homozygous resistance to thyroid hormone β: can combined antithyroid drug and triiodothyroacetic acid treatment prevent cardiac failure?. Journal of the Endocrine Society, 1(9), 1203-1212. https://doi.org/10.1210/js.2017-00204

Resistance to thyroid hormone β (RTHβ) due to homozygous THRB defects is exceptionally rare, with only five kindreds reported worldwide. Cardiac dysfunction, which can be life-threatening, is recognized in the disorder. Here we describe the clinical,... Read More about Homozygous resistance to thyroid hormone β: can combined antithyroid drug and triiodothyroacetic acid treatment prevent cardiac failure?.

Relationship between haemodynamic impairment and collateral blood flow in carotid artery disease (2017)
Journal Article
Hartkamp, N. S., Petersen, E. T., Chappell, M. A., Okell, T. W., Uyttenboogaart, M., Zeebregts, C. J., & Bokkers, R. P. (2018). Relationship between haemodynamic impairment and collateral blood flow in carotid artery disease. Journal of Cerebral Blood Flow and Metabolism, 38(11), 2021-2032. https://doi.org/10.1177/0271678x17724027

Collateral blood flow plays a pivotal role in steno-occlusive internal carotid artery (ICA) disease to prevent irreversible ischaemic damage. Our aim was to investigate the effect of carotid artery disease upon cerebral perfusion and cerebrovascular... Read More about Relationship between haemodynamic impairment and collateral blood flow in carotid artery disease.

Route of feeding as a proxy for dysphagia after stroke and the effect of transdermal glyceryl trinitrate: data from the efficacy of nitric oxide in stroke randomised controlled trial (2017)
Journal Article
Woodhouse, L. J., Scutt, P., Hamdy, S., Smithard, D., Cohen, D. L., Roffe, C., …Bath, P. M. (in press). Route of feeding as a proxy for dysphagia after stroke and the effect of transdermal glyceryl trinitrate: data from the efficacy of nitric oxide in stroke randomised controlled trial. Translational Stroke Research, 9(2), https://doi.org/10.1007/s12975-017-0548-0

Post-stroke dysphagia is common, associated with poor outcome and often requires non-oral feeding/fluids. The relationship between route of feeding and outcome, as well as treatment with glyceryl trinitrate (GTN), was studied prospectively. The Effic... Read More about Route of feeding as a proxy for dysphagia after stroke and the effect of transdermal glyceryl trinitrate: data from the efficacy of nitric oxide in stroke randomised controlled trial.

Predicting major bleeding in patients with noncardioembolic stroke on antiplatelets (2017)
Journal Article
Hilkens, N. A., Algra, A., Diener, H.-C., Reitsma, J. B., Bath, P. M., Csiba, L., …Greving, J. P. (2017). Predicting major bleeding in patients with noncardioembolic stroke on antiplatelets. Neurology, 89(9), https://doi.org/10.1212/WNL.0000000000004289

Objective: To develop and externally validate a prediction model for major bleeding in patients with a TIA or ischemic stroke on antiplatelet agents.

Methods: We combined individual patient data from 6 randomized clinical trials (CAPRIE, ESPS-2, M... Read More about Predicting major bleeding in patients with noncardioembolic stroke on antiplatelets.

Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053) (2017)
Journal Article
Appleton, J. P., Scutt, P., Dixon, M., Howard, H., Haywood, L., Havard, D., …Bath, P. M. (in press). Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053). International Journal of Stroke, https://doi.org/10.1177/1747493017724627

Rationale: Vascular nitric oxide levels are low in acute stroke and donors such as glyceryl trinitrate have shown promise when administered very early after stroke. Potential mechanisms of action include augmentation of cerebral reperfusion, thrombol... Read More about Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053).

Infections up to 76 days after stroke increase disability and death (2017)
Journal Article
Learoyd, A., Woodhouse, L. J., Shaw, L., Sprigg, N., Bereczki, D., Berge, E., …Trueman, R. C. (in press). Infections up to 76 days after stroke increase disability and death. Translational Stroke Research, https://doi.org/10.1007/s12975-017-0553-3

Early infection after stroke is associated with a poor outcome. We aimed to determine whether delayed infections (up to 76 days post-stroke) are associated with poor outcome at 90 days. Data came from the international Efficacy of Nitric Oxide Stroke... Read More about Infections up to 76 days after stroke increase disability and death.