Outputs (33)

Survival of corneal nerve/sheath structures in organ-cultured donor corneas (2017)
Journal Article

Purpose
To study the morphology of human corneal nerves in eye bank organ‐cultured corneas and in corneal grafts post‐transplantation.

Methods
Thirty‐seven organ‐cultured corneas were divided into: Group‐A, anterior 300–400 μm of 20 corneas used... Read More about Survival of corneal nerve/sheath structures in organ-cultured donor corneas.

Scrolling Characteristics of Pre-Descemet Endothelial Keratoplasty Tissue: An Ex Vivo Study (2016)
Journal Article

Purpose

To evaluate the scrolling propensity of pre-Descemet endothelial keratoplasty (PDEK) tissue and to compare it with each component of the PDEK tissue, namely the pre-Descemet layer (Dua's layer [PDL]) and the Descemet membrane (DM).

Desi... Read More about Scrolling Characteristics of Pre-Descemet Endothelial Keratoplasty Tissue: An Ex Vivo Study.

Corneal Decellularization: A Method of Recycling Unsuitable Donor Tissue for Clinical Translation? (2015)
Journal Article
Wilson, S. L., Sidney, L. E., Dunphy, S. E., Dua, H. S., & Hopkinson, A. (2016). Corneal Decellularization: A Method of Recycling Unsuitable Donor Tissue for Clinical Translation?. Current Eye Research, 41(6), 769-782. https://doi.org/10.3109/02713683.2015.1062114

Background: There is a clinical need for biomimetic corneas that are as effective, preferably superior, to cadaveric donor tissue. Decellularized tissues are advantageous compared to synthetic or semi-synthetic engineered tissues in that the native m... Read More about Corneal Decellularization: A Method of Recycling Unsuitable Donor Tissue for Clinical Translation?.

Corneal hypoesthesia with normal sub-basal nerve density following surgery for trigeminal neuralgia (2015)
Journal Article

Calcified corneal nerves (2015)
Journal Article

The collagen matrix of the human trabecular meshwork is an extension of the novel pre-Descemet's layer (Dua's layer) (2014)
Journal Article

Pre-Descemet's endothelial keratoplasty (PDEK) (2014)
Journal Article

A new surgical technique for endothelial keratoplasty is described, in which the composite of pre-Descemet's layer (Dua's layer) with Descemet's membrane and endothelium is transplanted subsequent to the removal of the recipient's Descemet's membrane... Read More about Pre-Descemet's endothelial keratoplasty (PDEK).

Anaesthetic corneas with intact sub-basal nerve plexus (2014)
Journal Article

Collagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting (2014)
Journal Article

Increased Expression of Hepcidin and Toll-Like Receptors 8 and 10 in Viral Keratitis (2011)
Journal Article
Mohammed, I., Abedin, A., Tsintzas, K., Abedin, S. A., Otri, A. M., Hopkinson, A., …Dua, H. S. (2011). Increased Expression of Hepcidin and Toll-Like Receptors 8 and 10 in Viral Keratitis. Cornea, 30(8), 899-904. https://doi.org/10.1097/ICO.0b013e31820126e5

Purpose:

Antimicrobial peptides (AMPs) and toll-like receptors (TLRs) form part of the “chemical barrier” of the ocular surface to microbes. Evidence suggests that pathogen recognition by TLR releases AMPs, altering AMP-TLR profiles in pathologic... Read More about Increased Expression of Hepcidin and Toll-Like Receptors 8 and 10 in Viral Keratitis.