SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons
(2012)
Journal Article
St Gelais, C., de Silva, S., Amie, S. M., Coleman, C. M., Hoy, H., Hollenbaugh, J. A., …Wu, L. (2012). SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons. Retrovirology, 9(1), Article 105. https://doi.org/10.1186/1742-4690-9-105
Outputs (3)
Cellular and Viral Mechanisms of HIV-1 Transmission Mediated by Dendritic Cells (2012)
Book Chapter
Coleman, C. M., St.Gelais, C., & Wu, L. (2012). Cellular and Viral Mechanisms of HIV-1 Transmission Mediated by Dendritic Cells. . Springer New York. https://doi.org/10.1007/978-1-4614-4433-6_4Dendritic cells (DCs) play a key role in the initial infection and cell-to-cell transmission events that occur upon HIV-1 infection. DCs interact closely with CD4+ T cells, the main target of HIV-1 replication. HIV-1 challenged DCs and target CD4+ T... Read More about Cellular and Viral Mechanisms of HIV-1 Transmission Mediated by Dendritic Cells.
HIV-1 Nef Enhances Dendritic Cell-Mediated Viral Transmission to CD4+ T Cells and Promotes T-Cell Activation (2012)
Journal Article
Wang, J., St. Gelais, C., Coleman, C. M., & Wu, L. (2012). HIV-1 Nef Enhances Dendritic Cell-Mediated Viral Transmission to CD4+ T Cells and Promotes T-Cell Activation. PLoS ONE, 7(3), Article e34521. https://doi.org/10.1371/journal.pone.0034521