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Outputs (23)

Social participation in the Promoting Activity, Independence and Stability in Early Dementia (PrAISED), a home-based therapy intervention for people living with dementia: a realist evaluation (2024)
Journal Article
Lorito, C. D., Pollock, K., Booth, V., Howe, L., Goldberg, S., Godfrey, M., Dunlop, M., Harwood, R. H., Van Der Wardt, V., & Lorito, C. D. (2024). Social participation in the Promoting Activity, Independence and Stability in Early Dementia (PrAISED), a home-based therapy intervention for people living with dementia: a realist evaluation. BMC Geriatrics, 24(1), Article 615. https://doi.org/10.1186/s12877-024-05086-y

Background. Interventions promoting social activity may reduce behavioural psychological symptoms and improve quality of life in people living with dementia. This study aimed to identify social benefits for participants living with dementia in the co... Read More about Social participation in the Promoting Activity, Independence and Stability in Early Dementia (PrAISED), a home-based therapy intervention for people living with dementia: a realist evaluation.

Establishing a research partnership to investigate functional loss and rehabilitation towards the end of life (2024)
Journal Article
Maddocks, M., Brighton, L. J., Connell, L., Cowley, A., Laird, B., Peryer, G., …Harwood, R. (2024). Establishing a research partnership to investigate functional loss and rehabilitation towards the end of life. Health Technology Assessment, 1-12. https://doi.org/10.3310/pthc7598

Background Functional loss, the inability to perform necessary or desired tasks, is a common consequence of life-limiting illnesses and associated symptoms (pain, fatigue, breathlessness, etc.) and causes suffering for patients and families. Rehabil... Read More about Establishing a research partnership to investigate functional loss and rehabilitation towards the end of life.

Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial (2024)
Journal Article
Howard, R., Cort, E., Rawlinson, C., Wiegand, M., Downey, A., Lawrence, V., …Gould, R. (2024). Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(4), 2990-2999. https://doi.org/10.1002/alz.13766

INTRODUCTION: Trials of effectiveness of treatment options for depression in dementia are an important priority. METHODS: Randomized controlled trial to assess adapted Problem Adaptation Therapy (PATH) for depression in mild/moderate dementia caused... Read More about Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial.

Whether from a position of strength or weakness, geriatric medicine has work to do to drive up standards in health care for older people (2023)
Journal Article
Gordon, A. L., Martin, F., Mistry, S., Harwood, R. H., & Dhesi, J. (2023). Whether from a position of strength or weakness, geriatric medicine has work to do to drive up standards in health care for older people. Age and Ageing, 52(11), Article afad208. https://doi.org/10.1093/ageing/afad208

• Geriatric medicine is the largest physicianly specialty in the UK, with high levels of competition for available training posts. • Improving care of older people has been the focus of multiple national policy initiatives in the UK over the past dec... Read More about Whether from a position of strength or weakness, geriatric medicine has work to do to drive up standards in health care for older people.

A rehabilitation intervention to improve recovery after an episode of delirium in adults over 65 years (RecoverED): study protocol for a multi-centre, single-arm feasibility study (2023)
Journal Article
Allan, L., O'Connell, A., Raghuraman, S., Bingham, A., Laverick, A., Chandler, K., …Clare, L. (2023). A rehabilitation intervention to improve recovery after an episode of delirium in adults over 65 years (RecoverED): study protocol for a multi-centre, single-arm feasibility study. Pilot and Feasibility Studies, 9, Article 162. https://doi.org/10.1186/s40814-023-01387-y

BackgroundDelirium affects over 20% of all hospitalised older adults. Delirium is associated with a number of adverse outcomes following hospital admission including cognitive decline, anxiety and depression, increased mortality and care needs. Previ... Read More about A rehabilitation intervention to improve recovery after an episode of delirium in adults over 65 years (RecoverED): study protocol for a multi-centre, single-arm feasibility study.

Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial (2023)
Journal Article
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., …Adams, E. (2023). Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial. BMJ, 382, Article e074787. https://doi.org/10.1136/bmj-2023-074787

Objective: To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared with usual care. Design: Randomised controlled trial. Setting: Participant... Read More about Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial.

The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study (2023)
Preprint / Working Paper
Swiderski, M., Vinogradova, Y., Knaggs, R., Harman, K., Harwood, R., Prasad, V., …Gran, S. The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study

Introduction Bullous pemphigoid (BP) is a serious skin disease that results in large painful blisters developing over the body and occurs most commonly in older people (over 70 years). Despite several comorbidities such as stroke and a threefold inc... Read More about The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study.

Incidence of cognitive impairment and dementia after hospitalisation for pneumonia: a UK population-based matched cohort study (2023)
Journal Article
Chalitsios, C. V., Baskaran, V., Harwood, R. H., Lim, W. S., & McKeever, T. M. (2023). Incidence of cognitive impairment and dementia after hospitalisation for pneumonia: a UK population-based matched cohort study. ERJ Open Research, 9(3), Article 00328-2022. https://doi.org/10.1183/23120541.00328-2022

Background Survivors of common infections may develop cognitive impairment or dementia; however, the risk of these conditions in people hospitalised with pneumonia is not well established. Methods A matched cohort study was conducted using Hospit... Read More about Incidence of cognitive impairment and dementia after hospitalisation for pneumonia: a UK population-based matched cohort study.

Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial (2023)
Preprint / Working Paper
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., Hoare, Z., Hancox, J., Bajwa, R., Burgon, C., Howe, L., Cowley, A., Bramley, T., Long, A., Lock, J., Tucker, R., Adams, E., O’Brien, R., Kearney, F., Kowalewska, K., …Masud, T. Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial

Background Dementia is associated with frailty leading to increased risks of falls and hospitalisations. Interventions are required to maintain functional ability, strength and balance. Design Multi-centre parallel group randomised controlled tria... Read More about Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial.