Outputs (27)

Programming of pluripotency and the germ line co-evolved from a Nanog ancestor (2025)
Journal Article
Crowley, D., Simpson, L., Chatfield, J., Forey, T., Allegrucci, C., Sang, F., Holmes, N., Genikhovich, G., Technau, U., Cunningham, D., Silva, E., Mullin, N., Dixon, J. E., Loose, M., Alberio, R., & Johnson, A. D. (2025). Programming of pluripotency and the germ line co-evolved from a Nanog ancestor. Cell Reports, 44(3), Article 115396. https://doi.org/10.1016/j.celrep.2025.115396

Francois Jacob proposed that evolutionary novelty arises through incremental tinkering with pre-existing genetic mechanisms. Vertebrate evolution was predicated on pluripotency—the ability of embryonic cells to form somatic germ-layers and primordial... Read More about Programming of pluripotency and the germ line co-evolved from a Nanog ancestor.

One Health tropical wetlands: a transdisciplinary framework for assessing the risks of emerging zoonotic diseases in the Brazilian Pantanal (2025)
Journal Article
de Oliveira Roque, F., Herrera, H. M., de Andrade, G. B., Johnson, M., Nunes, A. V., de Oliveira, A. G., de Castro Ferreira, E., Fernandes, G. W., Araujo, G. A., Santos, L. G. R. O., Chiaravalloti, R. M., de Lucena, R. F. P., Libonati, R., Wantzen, K. M., Tasker, A., Bowsher, G., Sullivan, R., & Yon, L. (2025). One Health tropical wetlands: a transdisciplinary framework for assessing the risks of emerging zoonotic diseases in the Brazilian Pantanal. Wetlands Ecology and Management, 33(1), Article 16. https://doi.org/10.1007/s11273-025-10031-w

The Pantanal wetland ecosystem of Brazil is experiencing unprecedented local challenges from anthropogenic pressures, as well as from global climate change. These pressures escalate the zoonotic risks from wildlife populations, whose own susceptibili... Read More about One Health tropical wetlands: a transdisciplinary framework for assessing the risks of emerging zoonotic diseases in the Brazilian Pantanal.

A single-cell atlas of pig gastrulation as a resource for comparative embryology (2024)
Journal Article
Simpson, L., Strange, A., Klisch, D., Kraunsoe, S., Azami, T., Goszczynski, D., Le Minh, T., Planells, B., Holmes, N., Sang, F., Henson, S., Loose, M., Nichols, J., & Alberio, R. (2024). A single-cell atlas of pig gastrulation as a resource for comparative embryology. Nature Communications, 15(1), Article 5210. https://doi.org/10.1038/s41467-024-49407-6

Cell-fate decisions during mammalian gastrulation are poorly understood outside of rodent embryos. The embryonic disc of pig embryos mirrors humans, making them a useful proxy for studying gastrulation. Here we present a single-cell transcriptomic at... Read More about A single-cell atlas of pig gastrulation as a resource for comparative embryology.

68. Effect of supplementation of amino acids on the post-pubertal growth, first lactation performance, and survival of Holstein Friesian dairy heifers (2024)
Journal Article
Farnan, K., & Margerison, J. (2024). 68. Effect of supplementation of amino acids on the post-pubertal growth, first lactation performance, and survival of Holstein Friesian dairy heifers. Animal - Science proceedings, 15(1), 75-76. https://doi.org/10.1016/j.anscip.2024.02.069

Introduction
During the first two to three weeks of lactation (fresh period), dairy cows experience concurrent negative energy and negative protein balance, where dietary intakes do not meet maintenance and production requirements. Consequently, ami... Read More about 68. Effect of supplementation of amino acids on the post-pubertal growth, first lactation performance, and survival of Holstein Friesian dairy heifers.

58. Effect of live yeast (Saccharomyces cerevisiae) on the health, and feed efficiency of rearing dairy calves (2024)
Journal Article
Farnan, K., & Margerison, J. (2024). 58. Effect of live yeast (Saccharomyces cerevisiae) on the health, and feed efficiency of rearing dairy calves. Animal - Science proceedings, 15(1), 64-65. https://doi.org/10.1016/j.anscip.2024.02.059

The growth rate and feed efficiency of dairy calves were greater when live yeast was added to the calf starter, which can lower the carbon footprint of, but not antimicrobial use in calf rearing. The morbidity in young calves is largely attributed to... Read More about 58. Effect of live yeast (Saccharomyces cerevisiae) on the health, and feed efficiency of rearing dairy calves.

57. Effect of live yeast (Saccharomyces cerevisiae) in calf starter feed on the health, and feed efficiency of rearing dairy calves (2024)
Journal Article
Farnan, K., & Margerison, J. (2024). 57. Effect of live yeast (Saccharomyces cerevisiae) in calf starter feed on the health, and feed efficiency of rearing dairy calves. Animal - Science proceedings, 15(1), 63-64

Conclusions Inter-rater agreement between participants for TUS6 was fair overall, with marked variation between raters and between technique performed. Agreement was improved when observers provided a binary score based upon lesion size, in compariso... Read More about 57. Effect of live yeast (Saccharomyces cerevisiae) in calf starter feed on the health, and feed efficiency of rearing dairy calves.

177. Effect of dietary digestible undegradable protein and amino acid concentration on the growth and development of post-pubertal dairy heifers (2023)
Journal Article
Farnan, K., Margerison, J., & Bartram, C. (2023). 177. Effect of dietary digestible undegradable protein and amino acid concentration on the growth and development of post-pubertal dairy heifers. Animal - Science proceedings, 14(2), 419. https://doi.org/10.1016/j.anscip.2023.01.554

Application Increasing the digestible undegradable protein (DUP) and amino acid (AA) concentration of post-pubertal dairy heifer diets by 12% provides an opportunity to increase the growth, stature, and feed efficiency of post-pubertal dairy heifers.... Read More about 177. Effect of dietary digestible undegradable protein and amino acid concentration on the growth and development of post-pubertal dairy heifers.

Transcription factor bHLH121 regulates root cortical aerenchyma formation in maize (2023)
Journal Article
Schneider, H. M., Lor, V. S., Zhang, X., Saengwilai, P., Hanlon, M. T., Klein, S. P., Davis, J. L., Borkar, A. N., Depew, C. L., Bennett, M. J., Kaeppler, S. M., Brown, K. M., Bhosale, R., & Lynch, J. P. (2023). Transcription factor bHLH121 regulates root cortical aerenchyma formation in maize. Proceedings of the National Academy of Sciences, 120(12), Article e2219668120. https://doi.org/10.1073/pnas.2219668120

Root anatomical phenotypes present a promising yet underexploited avenue to deliver major improvements in yield and climate resilience of crops by improving water and nutrient uptake. For instance, the formation of root cortical aerenchyma (RCA) sign... Read More about Transcription factor bHLH121 regulates root cortical aerenchyma formation in maize.

Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus (2023)
Journal Article
Edwards, A., Njaci, I., Sarkar, A., Jiang, Z., Kaithakottil, G. G., Moore, C., Cheema, J., Stevenson, C. E. M., Rejzek, M., Novák, P., Vigouroux, M., Vickers, M., Wouters, R. H. M., Paajanen, P., Steuernagel, B., Moore, J. D., Higgins, J., Swarbreck, D., Martens, S., Kim, C. Y., …Emmrich, P. M. F. (2023). Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus. Nature Communications, 14, Article 876. https://doi.org/10.1038/s41467-023-36503-2

Grass pea (Lathyrus sativus L.) is a rich source of protein cultivated as an insurance crop in Ethiopia, Eritrea, India, Bangladesh, and Nepal. Its resilience to both drought and flooding makes it a promising crop for ensuring food security in a chan... Read More about Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.

Curriculum reform in agricultural vocational education and training in Zimbabwe: Implementation challenges and possibilities (2022)
Journal Article
Muwaniki, C., McGrath, S., Manzeke-Kangara, M. G., Wedekind, V., & Chamboko, T. (2022). Curriculum reform in agricultural vocational education and training in Zimbabwe: Implementation challenges and possibilities. Journal of Vocational, Adult and Continuing Education and Training, 5(1), 94-115. https://doi.org/10.14426/jovacet.v5i1.248

There is a need for the agricultural technical vocational education and training curriculum in Zimbabwe to be reformed so that it can respond to changes in farmer demographics, the expanding roles of agricultural extension officers (AEOs), changes in... Read More about Curriculum reform in agricultural vocational education and training in Zimbabwe: Implementation challenges and possibilities.

89. Challenges and opportunities for farmers and calf rearers (2022)
Journal Article
Margerison, J. (2022). 89. Challenges and opportunities for farmers and calf rearers. Animal - Science proceedings, 13(1), 61-62. https://doi.org/10.1016/j.anscip.2022.03.090

Farmers and calf rearers aim to enhance animal health through disease prevention strategies included in herd health plans, which include investment in housing, biosecurity, hygiene and staff training that lower the cost of treatment (morbidity), labo... Read More about 89. Challenges and opportunities for farmers and calf rearers.

Development of Plant-Based Vaccines for Prevention of Avian Influenza and Newcastle Disease in Poultry (2022)
Journal Article
Nurzijah, I., Elbohy, O. A., Kanyuka, K., Daly, J. M., & Dunham, S. (2022). Development of Plant-Based Vaccines for Prevention of Avian Influenza and Newcastle Disease in Poultry. Vaccines, 10(3), Article 478. https://doi.org/10.3390/vaccines10030478

Viral diseases, including avian influenza (AI) and Newcastle disease (ND), are an important cause of morbidity and mortality in poultry, resulting in significant economic losses. Despite the availability of commercial vaccines for the major viral dis... Read More about Development of Plant-Based Vaccines for Prevention of Avian Influenza and Newcastle Disease in Poultry.

Physiological screening for drought tolerance traits in vegetable amaranth (Amaranthus tricolor) germplasm (2021)
Journal Article
Jamalluddin, N., Massawe, F. J., Mayes, S., Ho, W. K., Singh, A., & Symonds, R. C. (2021). Physiological screening for drought tolerance traits in vegetable amaranth (Amaranthus tricolor) germplasm. Agriculture, 11(10), Article 994. https://doi.org/10.3390/agriculture11100994

Amaranth (Amaranthus tricolor), an underutilized climate smart crop, is highly nutritious and possesses diverse drought tolerance traits, making it an ideal crop to thrive in a rapidly changing climate. Despite considerable studies on the growth and... Read More about Physiological screening for drought tolerance traits in vegetable amaranth (Amaranthus tricolor) germplasm.

The palaeoenvironmental potential of the eastern Jordanian desert basins (Qe'an) (2021)
Journal Article
Jones, M. D., Richter, T., Rollefson, G., Rowan, Y., Roe, J., Toms, P., Wood, J., Wasse, A., Ikram, H., Williams, M., AlShdaifat, A., Pedersen, P. N., & Esaid, W. (2021). The palaeoenvironmental potential of the eastern Jordanian desert basins (Qe'an). Quaternary International, https://doi.org/10.1016/j.quaint.2021.06.023

This paper presents a summary of work undertaken by the authors and their teams on a series of Qe'an (plural of Qa’), in the Badia of eastern Jordan. These basins are foci for settlement in the region, with the sites described here (Shubayqa, Wisad a... Read More about The palaeoenvironmental potential of the eastern Jordanian desert basins (Qe'an).

Plant gathering and people-environment interactions at Epipalaeolithic Kharaneh IV, Jordan (2021)
Journal Article
Bode, L. J. K., Livarda, A., & Jones, M. D. (2021). Plant gathering and people-environment interactions at Epipalaeolithic Kharaneh IV, Jordan. Vegetation History and Archaeobotany, https://doi.org/10.1007/s00334-021-00839-w

This paper presents the first archaeobotanical results on plant macroremains other than charcoal from the Early and Middle Epipalaeolithic site of Kharaneh IV in the Azraq basin, one of the largest Epipalaeolithic sites in the southern Levant and one... Read More about Plant gathering and people-environment interactions at Epipalaeolithic Kharaneh IV, Jordan.

164 Effect of atypical reproductive cycles on key performance indicators of reproductive efficiency in Holstein Friesian dairy cattle (2021)
Journal Article
Algherair, I., Garnsworthy, P., Margerison, J., & Mann, G. (2021). 164 Effect of atypical reproductive cycles on key performance indicators of reproductive efficiency in Holstein Friesian dairy cattle. Animal - Science proceedings, 12(1), 134. https://doi.org/10.1016/j.anscip.2021.03.165

Good reproductive performance is essential to the economic efficiency of dairy production. Previous studies reported that 31 to 46% of dairy cattle had reproductive problems [1]. However, few studies have assessed reproductive cycle length of high yi... Read More about 164 Effect of atypical reproductive cycles on key performance indicators of reproductive efficiency in Holstein Friesian dairy cattle.

108. Effect of environmental enrichment on feed intake, feed efficiency and cross-sucking of dairy bred calves offered high amounts of milk replacer twice daily (2021)
Journal Article
Margerison, J., & Hemmingway-Wood O'Dell, M. (2021). 108. Effect of environmental enrichment on feed intake, feed efficiency and cross-sucking of dairy bred calves offered high amounts of milk replacer twice daily. Animal - Science proceedings, 12(1), 87

Application: Cross sucking (CS) was almost eliminated in calves reared in pairs by bedding calves with straw directly following milk feeding, while feed efficiency (FE) was not affected. Artificially reared calves commonly suck each other following... Read More about 108. Effect of environmental enrichment on feed intake, feed efficiency and cross-sucking of dairy bred calves offered high amounts of milk replacer twice daily.

110. Effect of oligosaccharides on calf health, antimicrobial use, live-weight gain, feed intake and feed efficiency of dairy bred calves (2021)
Journal Article
Margerison, J., & Farnan, K. (2021). 110. Effect of oligosaccharides on calf health, antimicrobial use, live-weight gain, feed intake and feed efficiency of dairy bred calves. Animal - Science proceedings, 12(1), 89. https://doi.org/10.1016/j.anscip.2021.03.111

Morbidity in young calves is largely attributed to enteric disorders and respiratory disease [1] and antimicrobials are an integral part of livestock production. However, human mortality due to antimi-crobial resistant (AMR) bacteria is projected to... Read More about 110. Effect of oligosaccharides on calf health, antimicrobial use, live-weight gain, feed intake and feed efficiency of dairy bred calves.

Simulating land use changes, sediment yields, and pesticide use in the Upper Paraguay River Basin: Implications for conservation of the Pantanal wetland (2021)
Journal Article
de Oliveira Roque, F., Guerra, A., Johnson, M., Padovania, C., Corbi, J., Covich, A. P., Eaton, D., Moraes Tomas, W., Valente-Neto, F., Piovezan Borges, A. C., Pinho, A., Barufatii, A., do Amara Crispim, B., Dettogni Guariento, R., Helena da Silva Andrade, M., Tavares Rezende-Filho, A., Portela, R., Divina, M., César Sampaioda Silva, J., Bernadino, C., …Yon, L. (2021). Simulating land use changes, sediment yields, and pesticide use in the Upper Paraguay River Basin: Implications for conservation of the Pantanal wetland. Agriculture, Ecosystems and Environment, 314, 1-11. https://doi.org/10.1016/j.agee.2021.107405

As a consequence of accelerated and excessive use of pesticides in tropical regions, wilderness areas are under threat; this includes the Pantanal wetlands in the Upper Paraguay River Basin (UPRB). Using a Land Cover Land Use Change (LCLUC) modelling... Read More about Simulating land use changes, sediment yields, and pesticide use in the Upper Paraguay River Basin: Implications for conservation of the Pantanal wetland.

Cordycepin, a metabolite of Cordyceps militaris, reduces immune-related gene expression in insects (2020)
Journal Article
Woolley, V. C., Teakle, G. R., Prince, G., de Moor, C. H., & Chandler, D. (2020). Cordycepin, a metabolite of Cordyceps militaris, reduces immune-related gene expression in insects. Journal of Invertebrate Pathology, 177, Article 107480. https://doi.org/10.1016/j.jip.2020.107480

Hypocrealean entomopathogenic fungi (EPF) (Sordariomycetes, Ascomycota) are natural regulators of insect populations in terrestrial environments. Their obligately-killing life-cycle means that there is likely to be strong selection pressure for trait... Read More about Cordycepin, a metabolite of Cordyceps militaris, reduces immune-related gene expression in insects.