All Outputs (4178)

Transcriptional plasticity buffers genetic variation in zinc homeostasis (2019)
Journal Article
Pita-Barbosa, A., Ricachenevsky, F. K., Wilson, M., Dottorini, T., & Salt, D. E. (2019). Transcriptional plasticity buffers genetic variation in zinc homeostasis. Scientific Reports, 9, Article 19482. https://doi.org/10.1038/s41598-019-55736-0

In roots of Arabidopsis thaliana, Zn can be either loaded into the xylem for translocation to the shoot or stored in vacuoles. Vacuolar storage is achieved through the action of the Zn/Cd transporter HMA3 (Heavy Metal Atpase 3). The Col-0 accession h... Read More about Transcriptional plasticity buffers genetic variation in zinc homeostasis.

Improving the efficacy of selenium fertilizers for wheat biofortification (2019)
Journal Article
Ramkissoon, C., Degryse, F., da Silva, R. C., Baird, R., Young, S. D., Bailey, E. H., & McLaughlin, M. J. (2019). Improving the efficacy of selenium fertilizers for wheat biofortification. Scientific Reports, 9, https://doi.org/10.1038/s41598-019-55914-0

© 2019, The Author(s). Increasing the selenium (Se) concentration of staple crops by fertilization is a valuable pathway to increase Se in the human diet, thus preventing Se deficiency. A pot trial was set up to investigate whether the application of... Read More about Improving the efficacy of selenium fertilizers for wheat biofortification.

Multi-material 3D bioprinting of porous constructs for cartilage regeneration (2019)
Journal Article
Ruiz-Cantu, L., Gleadall, A., Faris, C., Segal, J., Shakesheff, K., & Yang, J. (2020). Multi-material 3D bioprinting of porous constructs for cartilage regeneration. Materials Science and Engineering: C, 109, https://doi.org/10.1016/j.msec.2019.110578

© 2020 Elsevier B.V. The current gold standard for nasal reconstruction after rhinectomy or severe trauma includes transposition of autologous cartilage grafts in conjunction with coverage using an autologous skin flap. Harvesting autologous cartilag... Read More about Multi-material 3D bioprinting of porous constructs for cartilage regeneration.

Confidence of recurrent cellulitis self-diagnosis among people with lymphoedema: a qualitative interview study (2019)
Journal Article
Patel, M., Lee, S. I., Levell, N. J., Smart, P., Kai, J., Thomas, K. S., & Leighton, P. (2020). Confidence of recurrent cellulitis self-diagnosis among people with lymphoedema: a qualitative interview study. British Journal of General Practice, 70(691), e130-e137. https://doi.org/10.3399/bjgp19X707909

© British Journal of General Practice 2020. BACKGROUND: Cellulitis can sometimes be challenging for healthcare professionals to diagnose, with no validated diagnostic criteria available. Supporting healthcare professionals to make a more accurate dia... Read More about Confidence of recurrent cellulitis self-diagnosis among people with lymphoedema: a qualitative interview study.

Clinical characteristics and patient treatment satisfaction with Humalog U-200 in patients with type 2 diabetes mellitus: an observational study (2019)
Journal Article
Mamza, J., Anyanwagu, U., Alkharaiji, M., & Idris, I. (2020). Clinical characteristics and patient treatment satisfaction with Humalog U-200 in patients with type 2 diabetes mellitus: an observational study. Journal of Drug Assessment, 9(1), 8-12. https://doi.org/10.1080/21556660.2019.1704415

Background There is limited data on the real world evidence of Humalog 200 units/ml KwikPen (U-200) insulin. We assessed the use of U-200 insulin in UK routine clinical practice to provide information on clinical characteristics, treatment satisfacti... Read More about Clinical characteristics and patient treatment satisfaction with Humalog U-200 in patients with type 2 diabetes mellitus: an observational study.

Liquidate your assets: reasoning about resource usage in liquid Haskell (2019)
Journal Article
Handley, M., Vazou, N., & Hutton, G. (2019). Liquidate your assets: reasoning about resource usage in liquid Haskell. Proceedings of the ACM on Programming Languages, 4, 1-27. https://doi.org/10.1145/3371092

Liquid Haskell is an extension to the type system of Haskell that supports formal reasoning about program correctness by encoding logical properties as refinement types. In this article, we show how Liquid Haskell can also be used to reason about pro... Read More about Liquidate your assets: reasoning about resource usage in liquid Haskell.

The Australian Real‐Time Fiscal Database: An Overview with Illustrations of Its Use in Analysing Fiscal Policy (2019)
Journal Article
Lee, K., Morley, J., Shields, K., & Tan, M. S. (2020). The Australian Real‐Time Fiscal Database: An Overview with Illustrations of Its Use in Analysing Fiscal Policy. Economic Record, 96(312), 87-106. https://doi.org/10.1111/1475-4932.12509

This paper describes a fiscal database for Australia including measures of government spending, revenue, deecits, debt and various sub-aggregates as initially published and subsequently revised. The data vintages are collated from various sources and... Read More about The Australian Real‐Time Fiscal Database: An Overview with Illustrations of Its Use in Analysing Fiscal Policy.

Exploring How Component Factors and Their Uncertainty Affect Judgements of Risk in Cyber-Security (2019)
Conference Proceeding
Ellerby, Z., McCulloch, J., Wilson, M., & Wagner, C. (2020). Exploring How Component Factors and Their Uncertainty Affect Judgements of Risk in Cyber-Security. In Critical Information Infrastructures Security: 14th International Conference, CRITIS 2019, Linköping, Sweden, September 23–25, 2019, Revised Selected Papers (31-42). https://doi.org/10.1007/978-3-030-37670-3_3

Subjective judgements from experts provide essential information when assessing and modelling threats in respect to cyber-physical systems. For example, the vulnerability of individual system components can be described using multiple factors, such a... Read More about Exploring How Component Factors and Their Uncertainty Affect Judgements of Risk in Cyber-Security.

Latest developments on the shielding effectiveness measurements of materials and gaskets in reverberation chambers (2019)
Journal Article
Gifuni, A., Gradoni, G., Smartt, C., Greedy, S., Villalón, A. M., Bastianelli, L., …Thomas, D. (2019). Latest developments on the shielding effectiveness measurements of materials and gaskets in reverberation chambers. IET Science Measurement and Technology, 14(4), 435-445. https://doi.org/10.1049/iet-smt.2019.0242

In this study, the authors present the latest developments on the measurements for the shielding effectiveness (SE) of gaskets and materials in reverberation chambers (RCs). A variant method, where the insertion loss of the fixture is achieved from t... Read More about Latest developments on the shielding effectiveness measurements of materials and gaskets in reverberation chambers.

Opportunities, Challenges And Risks Of Transition Into Renewable Energy : The Case Study Of Arab Gulf Cooperation Council (2019)
Journal Article
Darwish, S., Abdo, H., & Alsabuwaiee, W. (2019). Opportunities, Challenges And Risks Of Transition Into Renewable Energy : The Case Study Of Arab Gulf Cooperation Council. International Energy Journal, 18(4), 391-400

Gulf Cooperation Council (GCC) member states have abounded underground fossil fuel resources and high potentials for renewable energy (RE). However, given the Peak Oil Theory and the international climate change regulations and protocols, investments... Read More about Opportunities, Challenges And Risks Of Transition Into Renewable Energy : The Case Study Of Arab Gulf Cooperation Council.

Highlights 2019: fresh focus on health (2019)
Journal Article
Palmer, J., Bolton, C. E., Shrestha, P., Adhikari, P., & Karmacharya, B. (2019). Highlights 2019: fresh focus on health. Lancet, 394(10216), 2219-2236. https://doi.org/10.1016/s0140-6736%2819%2933060-0

Contribution towards Fresh focus on health: Highlights 2019 photography competition open for submissions. Palmer J. Lancet. 2019 Jun 8;393(10188):2284-2285. doi: 10.1016/S0140-6736(19)31258-9. Epub 2019 Jun 6 https://www.ncbi.nlm.nih.gov/pubm... Read More about Highlights 2019: fresh focus on health.

Moderating Loss Aversion: Loss Aversion Has Moderators, But Reports of its Death are Greatly Exaggerated (2019)
Journal Article
Herrmann, A., Mrkva, K., Gächter, S., & Johnson, E. J. (2020). Moderating Loss Aversion: Loss Aversion Has Moderators, But Reports of its Death are Greatly Exaggerated. Journal of Consumer Psychology, 30(3), 407-428. https://doi.org/10.1002/jcpy.1156

Loss aversion, the principle that losses impact decision making more than equivalent gains, is a fundamental idea in consumer behavior and decision making, though its existence has recently been called into question. Across five unique samples (Ntota... Read More about Moderating Loss Aversion: Loss Aversion Has Moderators, But Reports of its Death are Greatly Exaggerated.

Implementation, Evalution and Maintenance of a Social-Emotional Skills Training Program for Children with an Autism Spectrum Disorder in a Specialist School Setting (2019)
Journal Article
Beaumont, R. B., Smith-Merry, J., Costley, D., Howlin, P., Sofronoff, K., Roberts, J., …Einfeld, S. L. (2019). Implementation, Evalution and Maintenance of a Social-Emotional Skills Training Program for Children with an Autism Spectrum Disorder in a Specialist School Setting. International Journal of Special Education, 34(1), 95-108

Socialization difficulties in children with an Autism Spectrum Disorder (ASD) are often associated with peer rejection and impaired academic achievement. Schools might appear to offer an ideal setting for social-emotional skills (SES) instruction. Ho... Read More about Implementation, Evalution and Maintenance of a Social-Emotional Skills Training Program for Children with an Autism Spectrum Disorder in a Specialist School Setting.

Place and student subjectivities in Higher Education ‘cold spots’ (2019)
Journal Article
Henderson, H. (2020). Place and student subjectivities in Higher Education ‘cold spots’. British Journal of Sociology of Education, 41(3), 331-345. https://doi.org/10.1080/01425692.2019.1703646

This article uses an analytical framework informed by social geographies to explore the complex relationships between Higher Education Institution, undergraduate student and place. Drawing on findings from a qualitative study exploring the experience... Read More about Place and student subjectivities in Higher Education ‘cold spots’.

Ligand-induced conformational selection predicts the selectivity of cysteine protease inhibitors (2019)
Journal Article
Sartori, G. R., Leitão, A., Montanari, C. A., & Laughton, C. A. (2019). Ligand-induced conformational selection predicts the selectivity of cysteine protease inhibitors. PLoS ONE, 14(12), Article e0222055. https://doi.org/10.1371/journal.pone.0222055

Cruzain, a cysteine protease of Trypanosoma cruzi, is a validated target for the treatment of Chagas disease. Due to its high similarity in three-dimensional structure with human cathepsins and their sequence identity above 70% in the active site reg... Read More about Ligand-induced conformational selection predicts the selectivity of cysteine protease inhibitors.

Environmental and field characteristics associated with lameness in sheep: a study using a smartphone lameness app for data recording (2019)
Journal Article
Vittis, Y., & Kaler, J. (2019). Environmental and field characteristics associated with lameness in sheep: a study using a smartphone lameness app for data recording. Veterinary Record, https://doi.org/10.1136/vr.105476

Background: Sheep lameness is a major concern among farmers and policymakers with significant impacts on animal welfare standards as well as financial and production performance. The present study attempts to identify the relative importance of envir... Read More about Environmental and field characteristics associated with lameness in sheep: a study using a smartphone lameness app for data recording.

Frequency- and state-dependent effects of hippocampal neural disinhibition on hippocampal local field potential oscillations in anaesthetised rats (2019)
Other
Gwilt, M., Bauer, M., & Bast, T. (2019). Frequency- and state-dependent effects of hippocampal neural disinhibition on hippocampal local field potential oscillations in anaesthetised rats

Reduced inhibitory GABA function, so-called neural disinhibition, has been implicated in cognitive disorders, including schizophrenia and age-related cognitive decline. We previously showed in rats that hippocampal disinhibition by local microinfusio... Read More about Frequency- and state-dependent effects of hippocampal neural disinhibition on hippocampal local field potential oscillations in anaesthetised rats.

Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates (2019)
Journal Article
da Silva, R. A., Karlyshev, A. V., Oldfield, N. J., Wooldridge, K. G., Bayliss, C. D., Ryan, A., & Griffin, R. (2019). Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates. Frontiers in Microbiology, 10, https://doi.org/10.3389/fmicb.2019.02847

© Copyright © 2019 da Silva, Karlyshev, Oldfield, Wooldridge, Bayliss, Ryan and Griffin. Meningococcal lipoprotein, Factor H binding protein (FHbp), is the sole antigen of the Trumenba vaccine (Pfizer) and one of four antigens of the Bexsero vaccine... Read More about Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates.

Uncertainty model for a traceable stereo-photogrammetry system (2019)
Journal Article
Sims-Waterhouse, D., Isa, M., Piano, S., & Leach, R. (2020). Uncertainty model for a traceable stereo-photogrammetry system. Precision Engineering, 63, 1-9. https://doi.org/10.1016/j.precisioneng.2019.12.008

Through the computational modelling and experimental verification of a stereo-photogrammetry system, the expanded uncertainty on form measurement was estimated and was found to be , and for a 95% confidence interval (coverage factors of = 3.2, 2.0... Read More about Uncertainty model for a traceable stereo-photogrammetry system.

Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica (2019)
Journal Article
Elsheikha, H. M., Aziz, N., & Butt, A. (2020). Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica. Ecotoxicology and Environmental Safety, 190, https://doi.org/10.1016/j.ecoenv.2019.110054

© 2019 Elsevier Inc. Heavy metal exposure induces oxidative stress in terrestrial organisms, which they counteract via activation of antioxidant biomarkers. The present study investigated the effects of copper (Cu) and lead (Pb) on the total antioxid... Read More about Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica.