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All Outputs (151)

An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients (2020)
Journal Article
Levy, N., Quinlan, J., El‐Boghdadly, K., Fawcett, W. J., Agarwal, V., Bastable, R. B., …Macintyre, P. E. (2020). An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients. Anaesthesia, 76(4), 520-536. https://doi.org/10.1111/anae.15262

This international multidisciplinary consensus statement was developed to provide balanced guidance on the safe peri‐operative use of opioids in adults. An international panel of healthcare professionals evaluated the literature relating to postopera... Read More about An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients.

Turning ‘waiting lists’ for elective surgery into ‘preparation lists’ (2020)
Journal Article
Levy, N., Selwyn, D., & Lobo, D. (2021). Turning ‘waiting lists’ for elective surgery into ‘preparation lists’. British Journal of Anaesthesia, 126(1), 1-5. https://doi.org/10.1016/j.bja.2020.08.021

Waiting lists for surgery are an integral part of the UK National Health Service (NHS); they are used as a construct to ration surgery and to reduce costs, whilst simultaneously attempting to distribute limited health resources in an equitable manner... Read More about Turning ‘waiting lists’ for elective surgery into ‘preparation lists’.

Fasting and surgery timing (FaST) audit (2020)
Journal Article
El-Sharkawy, A. M., Daliya, P., Lewis-Lloyd, C., Adiamah, A., Malcolm, F. L., Boyd-Carson, H., …Wolff, J. (2021). Fasting and surgery timing (FaST) audit. Clinical Nutrition, 40(3), 1405-1412. https://doi.org/10.1016/j.clnu.2020.08.033

Background & aims International guidance advocates the avoidance of prolonged preoperative fasting due to its negative impact on perioperative hydration. This study aimed to assess the adherence to these guidelines for fasting in patients undergoi... Read More about Fasting and surgery timing (FaST) audit.

Major elective abdominal surgery acutely impairs lower limb muscle pyruvate dehydrogenase complex activity and mitochondrial function (2020)
Journal Article
Atkins, R., Constantin-Teodosiu, D., Varadhan, K. K., Constantin, D., Lobo, D. N., & Greenhaff, P. L. (2021). Major elective abdominal surgery acutely impairs lower limb muscle pyruvate dehydrogenase complex activity and mitochondrial function. Clinical Nutrition, 40(3), 1046-1051. https://doi.org/10.1016/j.clnu.2020.07.006

© 2020 The Author(s) Background & aims: This post hoc study aimed to determine whether major elective abdominal surgery had any acute impact on mitochondrial pyruvate dehydrogenase complex (PDC) activity and maximal mitochondrial ATP production rates... Read More about Major elective abdominal surgery acutely impairs lower limb muscle pyruvate dehydrogenase complex activity and mitochondrial function.

Hypertriglyceridaemia as a risk factor for critical care admission in acute pancreatitis: A prospective study (2020)
Journal Article
Adiamah, A., Kushairi, A., Tumulty, S., Na, Y., Crook, M., Brooks, A. J., …Nottingham University Hospitals Hepatopancreaticobiliary Team. (2020). Hypertriglyceridaemia as a risk factor for critical care admission in acute pancreatitis: A prospective study. Clinical Nutrition ESPEN, 39, 227-233. https://doi.org/10.1016/j.clnesp.2020.06.008

Background and aims Hypertriglyceridaemia is both a primary cause of acute pancreatitis and an epiphenomenon. This study aimed to define the associations between hypertriglyceridaemia and clinical outcomes in patients admitted with acute pancreatiti... Read More about Hypertriglyceridaemia as a risk factor for critical care admission in acute pancreatitis: A prospective study.

Perioperative nutrition: Recommendations from the ESPEN expert group (2020)
Journal Article
Lobo, D. N., Gianotti, L., Adiamah, A., Barazzoni, R., Deutz, N., Dhatariya, K., …Weimann, A. (2020). Perioperative nutrition: Recommendations from the ESPEN expert group. Clinical Nutrition, 39(11), 3211-3227. https://doi.org/10.1016/j.clnu.2020.03.038

© 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism Background & aims: Malnutrition has been recognized as a major risk factor for adverse postoperative outcomes. The ESPEN Symposium on perioperative nutrition was held in N... Read More about Perioperative nutrition: Recommendations from the ESPEN expert group.

The impact of peri-operative intravenous lidocaine on postoperative outcome after elective colorectal surgery: A meta-analysis of randomised controlled trials (2020)
Journal Article
Rollins, K. E., Javanmard-Emamghissi, H., Scott, M. J., & Lobo, D. N. (2020). The impact of peri-operative intravenous lidocaine on postoperative outcome after elective colorectal surgery: A meta-analysis of randomised controlled trials. European Journal of Anaesthesiology, 37(8), 659-670. https://doi.org/10.1097/eja.0000000000001165

BACKGROUND There has recently been increasing interest in the use of peri-operative intravenous lidocaine (IVL) due to its analgesic, anti-inflammatory and opioid-sparing effects. However, these potential benefits are not well established in electi... Read More about The impact of peri-operative intravenous lidocaine on postoperative outcome after elective colorectal surgery: A meta-analysis of randomised controlled trials.

ESPEN guideline on clinical nutrition in acute and chronic pancreatitis (2020)
Journal Article
Arvanitakis, M., Ockenga, J., Bezmarevic, M., Gianotti, L., Krznarić, Ž., Lobo, D. N., …Bischoff, S. (2020). ESPEN guideline on clinical nutrition in acute and chronic pancreatitis. Clinical Nutrition, 39(3), 612-631. https://doi.org/10.1016/j.clnu.2020.01.004

Both acute and chronic pancreatitis are frequent diseases of the pancreas, which, despite being of benign nature, are related to a significant risk of malnutrition and may require nutritional support. Acute necrotizing pancreatitis is encountered in... Read More about ESPEN guideline on clinical nutrition in acute and chronic pancreatitis.

Restoration of function: the holy grail of peri?operative care (2020)
Journal Article
Levy, N., Grocott, M., & Lobo, D. (2020). Restoration of function: the holy grail of peri?operative care. Anaesthesia, 75(S1), e14-e17. https://doi.org/10.1111/anae.14893

In this collaborative supplement published byAnaesthesiaand theBritish Journal of Surgery, there are reviews ofenhanced recovery after surgery in both the elective [1] andthe emergency patient [2] by Kehlet, a surgeon fromDenmark. These are complimen... Read More about Restoration of function: the holy grail of peri?operative care.

Response to the Comment on “Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials” (2019)
Journal Article
Chowdhury, A., Adiamah, A., Kushairi, A., & Lobo, D. (2021). Response to the Comment on “Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials”. Annals of Surgery, 274(6), e676-e677. https://doi.org/10.1097/SLA.0000000000003759

Recommendations from the ERAS® Society for standards for the development of enhanced recovery after surgery guidelines (2019)
Journal Article
Brindle, M., Nelson, G., Lobo, D. N., Ljungqvist, O., & Gustafsson, U. O. (2020). Recommendations from the ERAS® Society for standards for the development of enhanced recovery after surgery guidelines. BJS Open, 4(1), 157-163. https://doi.org/10.1002/bjs5.50238

Background ERAS® Society guidelines are holistic, multidisciplinary tools designed to improve outcomes after surgery. The enhanced recovery after surgery (ERAS) approach was initially developed for colorectal surgery and has been implemented success... Read More about Recommendations from the ERAS® Society for standards for the development of enhanced recovery after surgery guidelines.

Response to Comment on "Knight SR, et al.: The impact of preoperative immune modulating nutrition on outcomes in patients undergoing surgery for gastrointestinal cancer" (2019)
Journal Article
Adiamah, A., Sko?epa, P., Weimann, A., & Lobo, D. N. (2019). Response to Comment on "Knight SR, et al.: The impact of preoperative immune modulating nutrition on outcomes in patients undergoing surgery for gastrointestinal cancer". Annals of Surgery, 270(6), e128-e129. https://doi.org/10.1097/SLA.0000000000003340

Hyperosmolar dehydration: a predictor of kidney injury and outcome in hospitalised older adults (2019)
Journal Article
El-Sharkawy, A. M., Devonald, M. A. J., Humes, D. J., Sahota, O., & Lobo, D. N. (2020). Hyperosmolar dehydration: a predictor of kidney injury and outcome in hospitalised older adults. Clinical Nutrition, 39(8), P2593-2599. https://doi.org/10.1016/j.clnu.2019.11.030

© 2019 The Author(s) Background & aims: Hospitalised older adults are vulnerable to dehydration. However, the prevalence of hyperosmolar dehydration (HD) and its impact on outcome is unknown. Serum osmolality is not measured routinely but osmolarity,... Read More about Hyperosmolar dehydration: a predictor of kidney injury and outcome in hospitalised older adults.

A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics (2019)
Journal Article
Bradley, C. R., Bragg, D. D., Cox, E. F., El-Sharkawy, A. M., Buchanan, C. E., Chowdhury, A. H., …Lobo, D. N. (2020). A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics. Clinical Nutrition, 39(7), 2070-2079. https://doi.org/10.1016/j.clnu.2019.09.011

Background & aims Blood volume expanding properties of colloids are superior to crystalloids. In addition to oncotic/osmotic properties, the electrolyte composition of infusions may have important effects on visceral perfusion, with infusions contai... Read More about A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics.