Outputs (588)

Functional recovery is considered the most important target: a survey of dedicated professionals (2014)
Journal Article
Aahlin, E. K., von Meyenfeldt, M., Dejong, C. H., Ljungqvist, O., Fearon, K. C., Lobo, D. N., Demartines, N., Revhaug, A., Wigmore, S. J., & Lassen, K. (2014). Functional recovery is considered the most important target: a survey of dedicated professionals. Perioperative Medicine, 3(1), https://doi.org/10.1186/2047-0525-3-5

Background: The aim of this study was to survey the relative importance of postoperative recovery targets and perioperative care items, as perceived by a large group of international dedicated professionals.
Methods: A questionnaire with eight posto... Read More about Functional recovery is considered the most important target: a survey of dedicated professionals.

Stimulation of colonic motility by oral PEG electrolyte bowel preparation assessed by MRI: comparison of splitvssingle dose (2014)
Journal Article
Marciani, L., Garsed, K. C., Hoad, C. L., Fields, A., Fordham, I., Pritchard, S. E., Placidi, E., Murray, K., Chaddock, G., Costigan, C., Lam, C., Jalanka-Tuovinen, J., De Vos, W. M., Gowland, P. A., & Spiller, R. C. (2014). Stimulation of colonic motility by oral PEG electrolyte bowel preparation assessed by MRI: comparison of splitvssingle dose. Neurogastroenterology and Motility, 26(10), 1426-1436. https://doi.org/10.1111/nmo.12403

Gut reactions (2014)
Journal Article
Robinson, K. (2014). Gut reactions

Effect of a Perioperative, Cardiac Output–Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review (2014)
Journal Article
Lobo, D., MacDonald, N., Pearse, R. M., Parnell, W., Harrison, D. A., Niebrzegowska, E., Bodger, P., Gillies, M. A., Gallego, L., Blunt, M., McAlees, E., Ackland, G., Januszewska, M., Grocott, M. P., Smith, A., Ahern, A., Pearse, R., Griggs, K., Gillies, M., Scott, R., …Treasure, T. (2014). Effect of a Perioperative, Cardiac Output–Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review. Journal of the American Medical Association, 311(21), 2180-2190. https://doi.org/10.1001/jama.2014.5305

A Randomized, Controlled, Double-Blind Crossover Study on the Effects of 1-L Infusions of 6% Hydroxyethyl Starch Suspended in 0.9% Saline (Voluven) and a Balanced Solution (Plasma Volume Redibag) on Blood Volume, Renal Blood Flow Velocity, and Renal Cortical Tissue Perfusion in Healthy Volunteers (2014)
Journal Article
Chowdhury, A., Fox, E., Francis, S., & Lobo, D. (2014). A Randomized, Controlled, Double-Blind Crossover Study on the Effects of 1-L Infusions of 6% Hydroxyethyl Starch Suspended in 0.9% Saline (Voluven) and a Balanced Solution (Plasma Volume Redibag) on Blood Volume, Renal Blood Flow Velocity, and Renal Cortical Tissue Perfusion in Healthy Volunteers. Annals of Surgery, 259(5), 881–887. https://doi.org/10.1097/SLA.0000000000000324

Objective: We compared the effects of intravenous administration of 6% hydroxyethyl starch (maize-derived) in 0.9% saline (Voluven; Fresenius Kabi, Runcorn, United Kingdom) and a “balanced” preparation of 6% hydroxyethyl starch (potato-derived) [Plas... Read More about A Randomized, Controlled, Double-Blind Crossover Study on the Effects of 1-L Infusions of 6% Hydroxyethyl Starch Suspended in 0.9% Saline (Voluven) and a Balanced Solution (Plasma Volume Redibag) on Blood Volume, Renal Blood Flow Velocity, and Renal Cortical Tissue Perfusion in Healthy Volunteers.

Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus (2014)
Journal Article
Upton, A. L., Grove, J. I., Mahdi, A. A., Briggs, G. S., Milner, D. S., Rudolph, C. J., & Lloyd, R. G. (2014). Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus. Nucleic Acids Research, 42(9), 5702-5714. https://doi.org/10.1093/nar/gku228

RecG is a DNA translocase encoded by most species of bacteria. The Escherichia coli protein targets branched DNA substrates and drives the unwinding and rewinding of DNA strands. Its ability to remodel replication forks and to genetically interact wi... Read More about Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus.

Phenotypic Features of Crohn's Disease Associated With Failure of Medical Treatment (2014)
Journal Article
Dubeau, M., Moran, G. W., Kaplan, G. G., Yang, H., Seow, C. H., Fedorak, R. N., Dieleman, L. A., Barkema, H. W., Ghosh, S., & Panaccione, R. (2014). Phenotypic Features of Crohn's Disease Associated With Failure of Medical Treatment. Clinical Gastroenterology and Hepatology, 12(3), 434-442.e1. https://doi.org/10.1016/j.cgh.2013.08.026

Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia: A Randomized Clinical Trial (2014)
Journal Article
Phoa, K. N., van Vilsteren, F. G., Weusten, B. L., Bisschops, R., Schoon, E. J., Raganuth, K., Fullarton, G., Di Pietro, M., Ravi, N., Visser, M., Offerhaus, G. J., Seldenrijk, C. A., Meijer, S. L., ten Kate, F. J., Tijssen, J. G., & Bergman, J. J. (2014). Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia: A Randomized Clinical Trial. Journal of the American Medical Association, 311(12), 1209-1217. https://doi.org/10.1001/jama.2014.2511

Importance
Barrett esophagus containing low-grade dysplasia is associated with an increased risk of developing esophageal adenocarcinoma, a cancer with a rapidly increasing incidence in the western world.

Objective
To investigate whether end... Read More about Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia: A Randomized Clinical Trial.

A role for the vacuolating cytotoxin, VacA, in colonisation and Helicobacter pylori-induced metaplasia in the stomach (2014)
Journal Article
Winter, J., Letley, D., Cook, K., Rhead, J., Zaitoun, A., Ingram, R., Amilon, K., Croxall, N., Kaye, P., Robinson, K., & Atherton, J. (2014). A role for the vacuolating cytotoxin, VacA, in colonisation and Helicobacter pylori-induced metaplasia in the stomach. Journal of Infectious Diseases, 210(6), 954–963. https://doi.org/10.1093/infdis/jiu154

Carriage of Helicobacter pylori strains producing more active (s1/i1) forms of VacA is strongly associated with gastric adenocarcinoma. To our knowledge, we are the first to determine effects of different polymorphic forms of VacA on inflammation and... Read More about A role for the vacuolating cytotoxin, VacA, in colonisation and Helicobacter pylori-induced metaplasia in the stomach.

Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease (2014)
Journal Article
Mells, G., ARAVINTHAN, A., Allison, M., Leathart, J., Kotronen, A., Yki-Jarvinen, H., Daly, A. K., Day, C. P., Anstee, Q. M., & Alexander, G. (2014). Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease. Cell Cycle, 13(9), 1489-1494. https://doi.org/10.4161/cc.28471

Non-alcohol-related fatty liver disease (NAFLD) encompasses a wide spectrum, ranging from steatosis alone to steatohepatitis and fibrosis. Presence of steatohepatitis and fibrosis are key hallmarks of disease progression. Previous studies have demons... Read More about Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease.