Outputs (21)

Deuterium brain imaging at 7T during D2O dosing (2022)
Journal Article
Cocking, D., Damion, R. A., Franks, H., Jaconelli, M., Wilkinson, D., Brook, M., …Bowtell, R. (2023). Deuterium brain imaging at 7T during D2O dosing. Magnetic Resonance in Medicine, 89(4), 1514-1521. https://doi.org/10.1002/mrm.29539

Purpose To characterize the (2H) deuterium MR signal measured from human brain at 7T in participants loading with D2O to ˜1.5% enrichment over a six-week period. Methods 2H spectroscopy and imaging measurements were used to track the time-course... Read More about Deuterium brain imaging at 7T during D2O dosing.

A Comparison of T2 Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study (2020)
Journal Article
McGarry, B. L., Damion, R. A., Chew, I., Knight, M. J., Harston, G. W., Carone, D., …Kauppinen, R. A. (2020). A Comparison of T2 Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study. Journal of Central Nervous System Disease, 12, https://doi.org/10.1177/1179573520943314

Background: T2 relaxation-based magnetic resonance imaging (MRI) signals may provide onset time for acute ischemic strokes with an unknown onset. The ability of visual and quantitative MRI-based methods in a cohort of hyperacute ischemic stroke patie... Read More about A Comparison of T2 Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study.

Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain (2019)
Journal Article
Knight, M. J., Damion, R. A., McGarry, B. L., Bosnell, R., Jokivarsi, K. T., Gröhn, O. H., …Kauppinen, R. A. (2019). Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain. Biomedical Spectroscopy and Imaging, 8(1-2), 11-28. https://doi.org/10.3233/bsi-190185

BACKGROUND AND OBJECTIVE: In hyperacute ischaemic stroke, T2 of cerebral water increases with time. Quantifying this change may be informative of the extent of tissue damage and onset time. Our objective was to develop a user-unbiased method to measu... Read More about Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain.

Quantifying T2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients (2019)
Journal Article
Damion, R. A., Knight, M. J., McGarry, B. L., Bosnell, R., Jezzard, P., Harston, G. W., …Kauppinen, R. A. (2019). Quantifying T2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients. Physics in Medicine and Biology, 64(9), Article 095016. https://doi.org/10.1088/1361-6560/ab1442

The apparent diffusion coefficient (ADC) of cerebral water, as measured by diffusion MRI, rapidly decreases in ischaemia, highlighting a lesion in acute stroke patients. The MRI T2 relaxation time changes in ischaemic brain such that T2 in ADC lesion... Read More about Quantifying T2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients.

Observation of angular dependence of T1 in the human white matter at 3T (2019)
Journal Article
Knight, M., Damion, R., & Kauppinen, R. (2019). Observation of angular dependence of T1 in the human white matter at 3T. Biomedical Spectroscopy and Imaging, 7(3-4), 125-133. https://doi.org/10.3233/bsi-180183

Background and Objective: Multiple factors including chemical composition and microstructure influence relaxivity of tissue water in vivo. We have quantified T1 in the human white mater (WM) together with diffusion tensor imaging to study a possible... Read More about Observation of angular dependence of T1 in the human white matter at 3T.

Imaging of nuclear magnetic resonance spin-lattice relaxation activation energy in cartilage (2018)
Journal Article
Foster, R. J., Damion, R. A., Ries, M. E., Smye, S. W., McGonagle, D. G., Binks, D. A., & Radjenovic, A. (2018). Imaging of nuclear magnetic resonance spin-lattice relaxation activation energy in cartilage. Royal Society Open Science, 5(7), https://doi.org/10.1098/rsos.180221

Samples of human and bovine cartilage have been examined using magnetic resonance imaging to determine the proton nuclearmagnetic resonance spin-lattice relaxation time, T1, as a function of depth within the cartilage tissue. T1 was measured at five... Read More about Imaging of nuclear magnetic resonance spin-lattice relaxation activation energy in cartilage.

Grassmann variables and pseudoclassical Nuclear Magnetic Resonance (2016)
Journal Article
Damion, R. A. (2016). Grassmann variables and pseudoclassical Nuclear Magnetic Resonance. Diffusion Fundamentals, 26, 1-23

The concept of a propagator is useful and is a well-known object in diffusion NMR experiments. Here, we investigate the related concept; the propagator for the magnetization or the Green's function of the Torrey-Bloch equations. The magnetization pro... Read More about Grassmann variables and pseudoclassical Nuclear Magnetic Resonance.

The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage (2016)
Journal Article
Meng, Q., An, S., Damion, R. A., Jin, Z., Wilcox, R., Fisher, J., & Jones, A. (2017). The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage. Journal of the Mechanical Behavior of Biomedical Materials, 65, 439-453. https://doi.org/10.1016/j.jmbbm.2016.09.001

The highly inhomogeneous distribution of collagen fibrils may have important effects on the biphasic mechanics of articular cartilage. However, the effect of the inhomogeneity of collagen fibrils has mainly been investigated using simplified three-la... Read More about The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage.

A nuclear magnetic resonance study of water in aggrecan solutions (2016)
Journal Article
Foster, R. J., Damion, R. A., Baboolal, T. G., Smye, S. W., & Ries, M. E. (2016). A nuclear magnetic resonance study of water in aggrecan solutions. Royal Society Open Science, 3(3), https://doi.org/10.1098/rsos.150705

Aggrecan, a highly charged macromolecule found in articular cartilage, was investigated in aqueous salt solutions with proton nuclear magnetic resonance. The longitudinal and transverse relaxation rates were determined at two different field strength... Read More about A nuclear magnetic resonance study of water in aggrecan solutions.

A nondestructive method to distinguish the internal constituent architecture of the intervertebral discs using 9.4 tesla magnetic resonance imaging (2015)
Journal Article
Wijayathunga, V. N., Ridgway, J. P., Ingham, E., Treanor, D., Carey, D., Bulpitt, A., …Wilcox, R. K. (2015). A nondestructive method to distinguish the internal constituent architecture of the intervertebral discs using 9.4 tesla magnetic resonance imaging. Spine, 40(24), E1315-E1322. https://doi.org/10.1097/BRS.0000000000001075

Study Design. An in vitro study of the intervertebral disc (IVD) structure using 9.4T magnetic resonance imaging (MRI). Objective. Investigate the potential of ultrahigh-field strength MRI for higher quality 3-dimensional (3D) volumetric MRI datasets... Read More about A nondestructive method to distinguish the internal constituent architecture of the intervertebral discs using 9.4 tesla magnetic resonance imaging.