Outputs (828)

Native Apps versus Web Apps: which is best for healthcare applications? (2013)
Journal Article
Selvarajah, K., Craven, M. P., Massey, A., Crowe, J., Vedhara, K., & Raine-Fenning, N. (2013). Native Apps versus Web Apps: which is best for healthcare applications?. Lecture Notes in Artificial Intelligence, 8005, https://doi.org/10.1007/978-3-642-39262-7_22

Smartphone applications (Apps) provide a new way to deliver healthcare, illustrated by the fact that healthcare Apps are estimated to make up over 30% of new Apps currently being developed; with this number seemingly set to increase as the benefits b... Read More about Native Apps versus Web Apps: which is best for healthcare applications?.

Profiling strugglers in a graduate-entry medicine course at Nottingham: a retrospective case study (2012)
Journal Article
Garrud, P., & Yates, J. (2012). Profiling strugglers in a graduate-entry medicine course at Nottingham: a retrospective case study. BMC Medical Education, 12(Decemb), Article 8. https://doi.org/10.1186/1472-6920-12-124

Background

10-15% of students struggle at some point in their medicine course. Risk factors include weaker academic qualifications, male gender, mental illness, UK ethnic minority status, and poor study skills. Recent research on an undergraduate... Read More about Profiling strugglers in a graduate-entry medicine course at Nottingham: a retrospective case study.

Leukotriene B4 receptor locus gene characterisation and association studies in asthma (2012)
Journal Article
Tulah, A. S., Beghé, B., Barton, S. J., Holloway, J. W., & Sayers, I. (2012). Leukotriene B4 receptor locus gene characterisation and association studies in asthma. BMC Medical Genetics, 13(Novemb), Article 11. https://doi.org/10.1186/1471-2350-13-110

Background: Polymorphisms spanning genes involved in the production of leukotriene B4 (LTB4) e.g. ALOX5AP and
LTA4H are associated with asthma susceptibility, suggesting a role for LTB4 in disease. The contribution of LTB4
receptor polymorphism is... Read More about Leukotriene B4 receptor locus gene characterisation and association studies in asthma.

Heart rate variability and target organ damage in hypertensive patients (2012)
Journal Article
Melillo, P., Izzo, R., De Luca, N., & Pecchia, L. (2012). Heart rate variability and target organ damage in hypertensive patients. BMC Cardiovascular Disorders, 12(Novemb), Article 11. https://doi.org/10.1186/1471-2261-12-105

Background
We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).

Methods
A retrospective analysis was performed including 200 patients registered in... Read More about Heart rate variability and target organ damage in hypertensive patients.

Video feedback intervention: a case series in the context of childhood hearing impairment (2012)
Journal Article
James, D. M., Wadnerkar-Kamble, M. B., & Lam-Cassettari, C. (2012). Video feedback intervention: a case series in the context of childhood hearing impairment. International Journal of Language and Communication Disorders, 48(6), https://doi.org/10.1111/1460-6984.12039

Background:
Recent research shows that parental sensitivity can explain a significant and unique amount of growth in speech and language outcomes in children with cochlear implants. In this intervention study we explored the impact of an interventi... Read More about Video feedback intervention: a case series in the context of childhood hearing impairment.

Chondrocalcinosis is common in the absence of knee involvement (2012)
Journal Article
Abhishek, A., Doherty, S., Maciewicz, R., Muir, K., Zhang, W., & Doherty, M. (2012). Chondrocalcinosis is common in the absence of knee involvement. Arthritis Research and Therapy, 14(5), Article 5. https://doi.org/10.1186/ar4043

Introduction: We aimed to describe the distribution of radiographic chondrocalcinosis (CC) and to examine
whether metacarpophalangeal joint (MCPJ) calcification and CC at other joints occurs in the absence of knee
involvement.

Methods: This was... Read More about Chondrocalcinosis is common in the absence of knee involvement.

Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis (2012)
Journal Article
Hurley, M., Cámara, M., & Smyth, A. R. (2012). Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. European Respiratory Journal, 40(4), https://doi.org/10.1183/09031936.00042012

Pseudomonas aeruginosa chronically infects patients with cystic fibrosis and is associated with greater morbidity. There has been limited progress on the clinical development of new antibiotics with novel modes of action. This review addresses some o... Read More about Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis.

WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma (2012)
Journal Article
Rogers, H., Sousa, S., Salto, C., Arenas, E., Coyle, B., & Grundy, R. G. (2012). WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma. British Journal of Cancer, 107, https://doi.org/10.1038/bjc.2012.377

Background: Medulloblastoma is the most common malignant childhood brain tumour. Aberrant activation of the WNT/β-catenin pathway occurs in approximately 25% of medulloblastomas. However, its role in medulloblastoma pathogenesis is not understood.... Read More about WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma.

Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties (2012)
Journal Article
Henshaw, H., Clark, D. P., Kang, S., & Ferguson, M. A. (2012). Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties. Journal of Medical Internet Research, 14(4), Article e113. https://doi.org/10.2196/jmir.2036

BACKGROUND

The use of personal computers (PCs) and the Internet to provide health care information and interventions has increased substantially over the past decade. Yet the effectiveness of such an approach is highly dependent upon whether the t... Read More about Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties.

Combinatorial discovery of polymers resistant to bacterial attachment (2012)
Journal Article
Hook, A. L., Chang, C.-Y., Yang, J., Luckett, J., Cockayne, A., Atkinson, S., Mei, Y., Bayston, R., Irvine, D. J., Langer, R., Anderson, D. G., Williams, P., Davies, M. C., & Alexander, M. R. (2012). Combinatorial discovery of polymers resistant to bacterial attachment. Nature Biotechnology, 30(9), 868-875. https://doi.org/10.1038/nbt.2316

Bacterial attachment and subsequent biofilm formation pose key challenges to the optimal performance of medical devices. In this study, we determined the attachment of selected bacterial species to hundreds of polymeric materials in a high-throughput... Read More about Combinatorial discovery of polymers resistant to bacterial attachment.