Outputs (2655)

Superspreaders have lower gut microbial alpha-diversity and distinct gut microbial composition in a natural rodent population (2025)
Journal Article
Wanelik, K. M., Begon, M., Bradley, J. E., Fenn, J., Jackson, J. A., & Paterson, S. (2025). Superspreaders have lower gut microbial alpha-diversity and distinct gut microbial composition in a natural rodent population. Animal Microbiome, 7, Article 42. https://doi.org/10.1186/s42523-025-00411-1

The microbiome is well known to drive variation in host states (e.g. behaviour, immunity) that would be expected to modulate the spread of infectious disease—but the role of microbiotal interactions in promoting superspreading is poorly understood. S... Read More about Superspreaders have lower gut microbial alpha-diversity and distinct gut microbial composition in a natural rodent population.

Student perceptions of novel and traditional anatomy teaching tools in sport and exercise science (2025)
Journal Article
Noel-Barker, N. L., Billeter-Clark, R., Kluzek, S., Harlow, P., & Jacques, M. F. (2025). Student perceptions of novel and traditional anatomy teaching tools in sport and exercise science. Annals of Anatomy, 29(3), 401-412. https://doi.org/10.52083/GAMY1767

Anatomy teaching is considered a cornerstone of Sport and Exercise Science programmes, however has a wide array of teaching tools to consider. The present study has compared student perceptions of traditional anatomy teaching tools (cadaveric prosect... Read More about Student perceptions of novel and traditional anatomy teaching tools in sport and exercise science.

Use of polyethylene glycol precipitation and ultracentrifugation to enhance the sensitivity of hepatitis B virus DNA detection (2025)
Journal Article
Fu, M. X., Larralde, O., Mayne, R., Kean, K., Reid, K., Andersson, M., Golubchik, T., McKeating, J. A., Jarvis, L., Irving, W. L., Simmonds, P., & Harvala, H. (2025). Use of polyethylene glycol precipitation and ultracentrifugation to enhance the sensitivity of hepatitis B virus DNA detection. Journal of Clinical Virology, 178, Article 105802. https://doi.org/10.1016/j.jcv.2025.105802

Background: Sensitive molecular detection of hepatitis B virus (HBV) DNA is crucial for diagnosing and managing occult hepatitis. To improve the sensitivity of HBV DNA detection, we compared the effectiveness of polyethylene glycol (PEG) precipitatio... Read More about Use of polyethylene glycol precipitation and ultracentrifugation to enhance the sensitivity of hepatitis B virus DNA detection.

Comparative genomics reveals common diversity and adaptation to harsh environments in the Arabian Peninsula indigenous chickens (2025)
Journal Article
Assiri, A., Vallejo-Trujillo, A., Al-Abri, M., Bahbahani, H., Almathen, F., Ahbara, A., Al Marzooqi, W., Tijjani, A., Lawal, R., & Hanotte, O. (2025). Comparative genomics reveals common diversity and adaptation to harsh environments in the Arabian Peninsula indigenous chickens. Animal Genetics, 56(3), Article e70014. https://doi.org/10.1111/age.70014

Identifying genomic regions under selection is crucial for comprehending the evolutionary history of the domestic chicken. Arabian Peninsula (AP) indigenous chickens are mostly found outdoors, being reared alongside other livestock for production pur... Read More about Comparative genomics reveals common diversity and adaptation to harsh environments in the Arabian Peninsula indigenous chickens.

Drug-like Antagonists of P2Y Receptor Subtypes: An Update (2025)
Journal Article
Puthanveedu, M., Knight, R., & Stocks, M. J. (2025). Drug-like Antagonists of P2Y Receptor Subtypes: An Update. Journal of Medicinal Chemistry, 68(9), 9057–9083. https://doi.org/10.1021/acs.jmedchem.5c00249

The hunt for drug-like P2YR antagonists continues, stimulated by ever-increasing pharmacological evidence for their clinical benefit and the astonishing array of biological functions which they orchestrate, including platelet aggregation, cancer prol... Read More about Drug-like Antagonists of P2Y Receptor Subtypes: An Update.

Identification of an a-factor-like pheromone secreted by the heterothallic ascomycete Aspergillus fumigatus (2025)
Journal Article
Krappmann, S., Gabl, E., Pazen, T., Heizmann, A., Pöggeler, S., Krüger, T., Kniemeyer, O., Einsiedel, J., Gmeiner, P., Yu, Y., Dyer, P. S., Baker, S. E., & Nowrousian, M. (2025). Identification of an a-factor-like pheromone secreted by the heterothallic ascomycete Aspergillus fumigatus. Current Biology, https://doi.org/10.1016/j.cub.2025.03.080

Members of the fungal kingdom serve as models for numerous cellular processes, among them sexuality. In heterothallic ascomycetes, mating-type systems ensure that only compatible isolates fuse to enter the sexual phase. This includes reciprocal secre... Read More about Identification of an a-factor-like pheromone secreted by the heterothallic ascomycete Aspergillus fumigatus.

Involvement of purinergic signalling in the vasomotor response to hypochlorous acid in porcine coronary artery (2025)
Journal Article
Baghdadi, A., Dunn, W. R., & Ralevic, V. (2025). Involvement of purinergic signalling in the vasomotor response to hypochlorous acid in porcine coronary artery. Purinergic Signalling, https://doi.org/10.1007/s11302-025-10086-7

Hypochlorous acid (HOCl) is generated by neutrophils during the innate immune response. ATP is released from cells by various stimuli and during inflammation but whether ATP is released by and participates in the response to HOCl is unclear. This stu... Read More about Involvement of purinergic signalling in the vasomotor response to hypochlorous acid in porcine coronary artery.

Growth resilience to weather variation in commercial free-ranging chickens in Ethiopia (2025)
Journal Article
Banos, G., Girma, M., Solomon, B., Davoudi, P., Esatu, W., Dessie, T., Psifidi, A., Watson, K., Hanotte, O., & Sánchez-Molano, E. (2025). Growth resilience to weather variation in commercial free-ranging chickens in Ethiopia. BMC Genomics, 26(1), Article 371. https://doi.org/10.1186/s12864-025-11561-6

Background: The poultry industry in sub-Saharan Africa is a rapidly developing sector mostly based on smallholder farming. Increased demand for poultry-derived products, driven by the growing economy and population, has intensified importations of hi... Read More about Growth resilience to weather variation in commercial free-ranging chickens in Ethiopia.

Lessons from the PROTECT-CH COVID-19 platform trial in care homes (2025)
Journal Article
Bath, P. M., Ball, J., Boyd, M., Gage, H., Glover, M., Godfrey, M., Guthrie, B., Hewitt, J., Howard, R., Jaki, T., Juszczak, E., Lasserson, D., Leighton, P., Leyland, V., Shen Lim, W., Logan, P., Meakin, G., Montgomery, A., Ogollah, R., Passmore, P., …Gordon, A. L. (2025). Lessons from the PROTECT-CH COVID-19 platform trial in care homes. Health Technology Assessment, https://doi.org/10.3310/MTRS8833

Background
Coronavirus disease-2019 was associated with significant mortality and morbidity in care homes in 2020–1. Repurposed antiviral drugs might reduce morbidity and mortality through reducing viral transmission, infection, replication and infl... Read More about Lessons from the PROTECT-CH COVID-19 platform trial in care homes.

Impact of Psychological Stress and Spontaneous Tumour Regression on the Hippocampal Proteome in a Mouse Model of Breast Cancer (2025)
Journal Article
Mampay, M., Al‐Hity, G., Rolle, S. O., Alzboon, W., Stewart, N. A., Flint, M. S., & Sheridan, G. K. (2025). Impact of Psychological Stress and Spontaneous Tumour Regression on the Hippocampal Proteome in a Mouse Model of Breast Cancer. Journal of Neurochemistry, 169(4), Article e70052. https://doi.org/10.1111/jnc.70052

Cognitive impairment is common in people diagnosed with breast cancer, but the molecular mechanisms that underlie maladaptive changes in the brain are unknown. The psychological stress of a cancer diagnosis is certainly a contributing factor. Here, w... Read More about Impact of Psychological Stress and Spontaneous Tumour Regression on the Hippocampal Proteome in a Mouse Model of Breast Cancer.