Outputs (2)

Enhanced localized pressure-mediated non-viral gene delivery (2025)
Journal Article
Dixon, J. E., Wellington, V., Elnima, A., Savers, A., Blokpoel Ferreras, L. A., Jalal, A. R., & Eltaher, H. M. (2025). Enhanced localized pressure-mediated non-viral gene delivery. Drug Delivery and Translational Research, https://doi.org/10.1007/s13346-025-01827-7

Topically applied therapies must not only be effective at the molecular level but also efficiently access the target site which can be on milli/centimetre-scales. This bottleneck is particularly inhibitory for peptide and nucleic acid macromolecule d... Read More about Enhanced localized pressure-mediated non-viral gene delivery.

A Modified Cell-Penetrating Peptide Enhances Insulin and Oxytocin Delivery across an RPMI 2650 Nasal Epithelial Cell Barrier In Vitro (2024)
Journal Article
Wong, S., Brown, A. D., Abrahams, A. B., Nurzak, A. N., Eltaher, H. M., Sykes, D. A., Veprintsev, D. B., Fone, K. C., Dixon, J. E., & King, M. V. (2024). A Modified Cell-Penetrating Peptide Enhances Insulin and Oxytocin Delivery across an RPMI 2650 Nasal Epithelial Cell Barrier In Vitro. Pharmaceutics, 16(10), Article 1267. https://doi.org/10.3390/pharmaceutics16101267

Background/Objectives: Peptide-based treatments represent an expanding area and require innovative approaches to enhance bioavailability. Combination with cell-penetrating peptides (CPPs) is an attractive strategy to improve non-invasive delivery acr... Read More about A Modified Cell-Penetrating Peptide Enhances Insulin and Oxytocin Delivery across an RPMI 2650 Nasal Epithelial Cell Barrier In Vitro.