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Outputs (3)

Sex drives colonic mucin sialylation in wild mice (2024)
Journal Article
Bennett, A. R., Mair, I., Muir, A., Smith, H., Logunova, L., Wolfenden, A., Fenn, J., Lowe, A. E., Bradley, J. E., Else, K. J., & Thornton, D. J. (in press). Sex drives colonic mucin sialylation in wild mice. Scientific Reports, 14, Article 6954. https://doi.org/10.1038/s41598-024-57249-x

Mucin protein glycosylation is important in determining biological properties of mucus gels, which form protective barriers at mucosal surfaces of the body such as the intestine. Ecological factors including: age, sex, and diet can change mucus barri... Read More about Sex drives colonic mucin sialylation in wild mice.

The wild mouse bone marrow has a unique myeloid and lymphoid composition and phenotype (2023)
Journal Article
Muir, A., Bennett, A., Smith, H., Logunova, L., Wolfenden, A., Fenn, J., Lowe, A. E., Brass, A., Grainger, J. R., Konkel, J. E., Bradley, J. E., Mair, I., & Else, K. J. (2023). The wild mouse bone marrow has a unique myeloid and lymphoid composition and phenotype. Discovery Immunology, 2(1), Article kyad005. https://doi.org/10.1093/discim/kyad005

The murine bone marrow has a central role in immune function and health as the primary source of leukocytes in adult mice. Laboratory mice provide a human-homologous, genetically manipulable and reproducible model that has enabled an immeasurable vol... Read More about The wild mouse bone marrow has a unique myeloid and lymphoid composition and phenotype.

A lesson from the wild: The natural state of eosinophils is Ly6Ghi (2021)
Journal Article
Mair, I., Wolfenden, A., Lowe, A. E., Bennett, A., Muir, A., Smith, H., Fenn, J., Bradley, J. E., & Else, K. J. (2021). A lesson from the wild: The natural state of eosinophils is Ly6Ghi. Immunology, 164(4), 766-776. https://doi.org/10.1111/imm.13413

With a long history of promoting pathological inflammation, eosinophils are now emerging as important regulatory cells. Yet, findings from controlled laboratory experiments so far lack translation to animals, including humans, in their natural enviro... Read More about A lesson from the wild: The natural state of eosinophils is Ly6Ghi.