Outputs (170)

Recombinant H77C gpE1/gpE2 heterodimer elicits superior HCV cross-neutralisation than H77C gpE2 alone (2024)
Journal Article
Kundu, J., Le, H. T., Logan, M., Hockman, D., Landi, A., Crawford, K., Wininger, M., Johnson, J., Kundu, J. K., Tiffney, E. A., Urbanowicz, R. A., Ball, J. K., Bailey, J. R., Bukh, J., Law, M., Foung, S., Tyrrell, D. L., Houghton, M., & Law, J. L. (2024). Recombinant H77C gpE1/gpE2 heterodimer elicits superior HCV cross-neutralisation than H77C gpE2 alone. Journal of Hepatology, 81(6), 941-948. https://doi.org/10.1016/j.jhep.2024.06.029

Background & Aims: An optimal HCV vaccine requires the induction of antibodies that neutralise the infectivity of many heterogenous viral isolates. In this study, we have focused on determining the optimal recombinant envelope glycoprotein component... Read More about Recombinant H77C gpE1/gpE2 heterodimer elicits superior HCV cross-neutralisation than H77C gpE2 alone.

Ion-combination specific effects driving the enzymatic activity of halophilic alcohol dehydrogenase 2 from Haloferax volcanii in aqueous ionic liquid solvent mixtures (2024)
Journal Article
Schindl, A., Hagen, M. L., Cooley, I., Jäger, C. M., Warden, A. C., Zelzer, M., Allers, T., & Croft, A. K. (2024). Ion-combination specific effects driving the enzymatic activity of halophilic alcohol dehydrogenase 2 from Haloferax volcanii in aqueous ionic liquid solvent mixtures. RSC Sustainability, 2(9), 2559-2580. https://doi.org/10.1039/d3su00412k

Biocatalysis in ionic liquids enables novel routes for bioprocessing. Enzymes derived from extremophiles promise greater stability and activity under ionic liquid (IL) influence. Here, we probe the enzyme alcohol dehydrogenase 2 from the halophilic a... Read More about Ion-combination specific effects driving the enzymatic activity of halophilic alcohol dehydrogenase 2 from Haloferax volcanii in aqueous ionic liquid solvent mixtures.

Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals (2024)
Journal Article
Miller, T. H., Schiessler, S., Rogerson, E. M., & Gadelha, C. (2024). Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals. The Cell Surface, 12, Article 100131. https://doi.org/10.1016/j.tcsw.2024.100131

The segregation of glycosylphosphatidylinositol-anchored proteins (GPI-APs) to distinct domains on the plasma membrane of eukaryotic cells is important for their correct cellular function, but the mechanisms by which GPI-APs are sorted are yet to be... Read More about Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals.

Thermal tolerance plasticity and dynamics of thermal tolerance in Eublepharis macularius: Implications for future climate-driven heat stress (2024)
Journal Article
White, E., Kim, S., Wegh, G., & Chiari, Y. (2024). Thermal tolerance plasticity and dynamics of thermal tolerance in Eublepharis macularius: Implications for future climate-driven heat stress. Journal of Thermal Biology, 123, Article 103912. https://doi.org/10.1016/j.jtherbio.2024.103912

The intensity and duration of heat waves, as well as average global temperatures, are expected to increase due to climate change. Heat waves can cause physiological stress and reduce fitness in animals. Species can reduce overheating risk through phe... Read More about Thermal tolerance plasticity and dynamics of thermal tolerance in Eublepharis macularius: Implications for future climate-driven heat stress.

How does viewing angle affect the perceived accuracy of Batesian mimicry in hoverflies? (2024)
Journal Article
Baker, L., Taylor, C., Gilbert, F., & Reader, T. (2024). How does viewing angle affect the perceived accuracy of Batesian mimicry in hoverflies?. Behavioral Ecology, 35(5), Article arae054. https://doi.org/10.1093/beheco/arae054

Despite Batesian mimicry often eliciting predator avoidance, many Batesian mimics, such as some species of hoverfly (Syrphidae), are considered to have an “imperfect” resemblance to their model. One possible explanation for the persistence of apparen... Read More about How does viewing angle affect the perceived accuracy of Batesian mimicry in hoverflies?.

Reconstruction of the historic time course of blood‐borne virus contamination of clotting factor concentrates, 1974–1992 (2024)
Journal Article
McClure, C. P., Kean, K., Reid, K., Mayne, R., Fu, M. X., Rajendra, P., Gates, S., Breuer, J., Harvala, H., Golubchik, T., Tarr, A. W., Irving, W. L., Makris, M., & Simmonds, P. (2024). Reconstruction of the historic time course of blood‐borne virus contamination of clotting factor concentrates, 1974–1992. Journal of Medical Virology, 96(7), Article e29774. https://doi.org/10.1002/jmv.29774

Factor VIII and IX clotting factor concentrates manufactured from pooled plasma have been identified as potent sources of virus infection in persons with hemophilia (PWHs) in the 1970s and 1980s. To investigate the range and diversity of viruses over... Read More about Reconstruction of the historic time course of blood‐borne virus contamination of clotting factor concentrates, 1974–1992.

Effect of change in hepato-renal function and cardiac rehabilitation on mortality in patients with heart failure. (2024)
Journal Article
Noda, T., Kamiya, K., Hamazaki, N., Nozaki, K., Uchida, S., Ueno, K., Miki, T., Hotta, K., Maekawa, E., Terada, T., Reed, J. L., Yamaoka-Tojo, M., Matsunaga, A., & Ako, J. (2024). Effect of change in hepato-renal function and cardiac rehabilitation on mortality in patients with heart failure. Journal of Cardiology, 84(6), 355-361. https://doi.org/10.1016/j.jjcc.2024.06.006

Patients with heart failure (HF) often suffer from hepato-renal dysfunction. The associations between hepato-renal function changes and mortality remain unclear. Further, the effect of cardiac rehabilitation (CR) on mortality and motor functions in p... Read More about Effect of change in hepato-renal function and cardiac rehabilitation on mortality in patients with heart failure..

High endemic freshwater mussel (Bivalvia: Unionida) diversity in western Borneo, with description of three new species (2024)
Journal Article
Zieritz, A., Pfeiffer, J., Rahim, K. A. A., Prayogo, H., Anwari, M. S., Diba, F., Froufe, E., Blackwell, T., Hartikainen, H., & Lopes-Lima, M. (2024). High endemic freshwater mussel (Bivalvia: Unionida) diversity in western Borneo, with description of three new species. Zoological Journal of the Linnean Society, 201(3), Article zlae076. https://doi.org/10.1093/zoolinnean/zlae076

The freshwater mussels (Bivalvia: Unionida) of the biodiversity hotspot Sundaland are experiencing severe anthropogenic threats, whilst their diversity and distribution remain poorly understood. Here, we present the first modern-day data on Unionida... Read More about High endemic freshwater mussel (Bivalvia: Unionida) diversity in western Borneo, with description of three new species.

Targeting Macrophage Polarization for Reinstating Homeostasis following Tissue Damage (2024)
Journal Article
Du, Q., Dickinson, A., Nakuleswaran, P., Maghami, S., Alagoda, S., Hook, A. L., & Ghaemmaghami, A. M. (2024). Targeting Macrophage Polarization for Reinstating Homeostasis following Tissue Damage. International Journal of Molecular Sciences, 25(13), Article 7278. https://doi.org/10.3390/ijms25137278

Tissue regeneration and remodeling involve many complex stages. Macrophages are critical in maintaining micro-environmental homeostasis by regulating inflammation and orchestrating wound healing. They display high plasticity in response to various st... Read More about Targeting Macrophage Polarization for Reinstating Homeostasis following Tissue Damage.

Genomic Analysis of Aspergillus Section Terrei Reveals a High Potential in Secondary Metabolite Production and Plant Biomass Degradation (2024)
Journal Article
Theobald, S., Vesth, T. C., Geib, E., Nybo, J. L., Frisvad, J. C., Larsen, T. O., Kuo, A., LaButti, K., Lyhne, E. K., Kjærbølling, I., Ledsgaard, L., Barry, K., Clum, A., Chen, C., Nolan, M., Sandor, L., Lipzen, A., Mondo, S., Pangilinan, J., Salamov, A., …Andersen, M. R. (2024). Genomic Analysis of Aspergillus Section Terrei Reveals a High Potential in Secondary Metabolite Production and Plant Biomass Degradation. Journal of Fungi, 10(7), Article 507. https://doi.org/10.3390/jof10070507

Aspergillus terreus has attracted interest due to its application in industrial biotechnology, particularly for the production of itaconic acid and bioactive secondary metabolites. As related species also seem to possess a prosperous secondary metabo... Read More about Genomic Analysis of Aspergillus Section Terrei Reveals a High Potential in Secondary Metabolite Production and Plant Biomass Degradation.