Skip to main content

Research Repository

Advanced Search

Outputs (107)

Defining within-host SARS-CoV-2 RNA viral load kinetics during acute COVID-19 infection within different respiratory compartments and their respective associations with host infectiousness: a protocol for a systematic review and meta-analysis (2024)
Journal Article
Pan, D., Martin, C. A., Nazareth, J., Sze, S., Al-Oraibi, A., Gogoi, M., Grolmusova, N., Divall, P., Decker, J., Fletcher, E., Williams, C., Hay, J., Baggaley, R. F., Wyllie, A. L., Stephenson, I., Gaillard, E., Nellums, L. B., Clark, T. W., Van-Tam, J. N., Cowling, B. J., …Pareek, M. (2024). Defining within-host SARS-CoV-2 RNA viral load kinetics during acute COVID-19 infection within different respiratory compartments and their respective associations with host infectiousness: a protocol for a systematic review and meta-analysis. BMJ Open, 14(12), Article e085127. https://doi.org/10.1136/bmjopen-2024-085127

Introduction: Understanding how RNA viral load changes (viral load kinetics) during acute infection in SARS-CoV-2 can help to identify when and which patients are most infectious. We seek to summarise existing data on the longitudinal RNA viral load... Read More about Defining within-host SARS-CoV-2 RNA viral load kinetics during acute COVID-19 infection within different respiratory compartments and their respective associations with host infectiousness: a protocol for a systematic review and meta-analysis.

Attitudes and current practice in alcohol screening, brief intervention, and referral for treatment among staff working in urgent and emergency settings: a survey (2023)
Presentation / Conference Contribution
Blake, H., Yildirim, M., Premakumar, V., Morris, L., Miller, P., & Coffey, F. (2023, June). Attitudes and current practice in alcohol screening, brief intervention, and referral for treatment among staff working in urgent and emergency settings: a survey. Presented at Tomorrow’s Doctors Conference 2023, London, UK

The Care and Management of Children and Young People with Ataxia Telangiectasia Provided by Nurses and Allied Health Professionals: a Scoping Review (2023)
Journal Article
Khan, M., Cassidy, E., Parkin, T., Wallace, A., Carter, B., Paton, J., Donohue, K., Mitchell, S., Quin, G., McNarry, N., Hartley, H., Bailey, H., Whitehouse, W., Medd, R., Zahidi, A., McMullan, M., & Bunn, L. (2023). The Care and Management of Children and Young People with Ataxia Telangiectasia Provided by Nurses and Allied Health Professionals: a Scoping Review. Cerebellum, https://doi.org/10.1007/s12311-023-01555-z

Ataxia telangiectasia (A-T) is a rare, multisystem progressive condition that typically presents in early childhood. In the absence of cure, people with A-T require coordinated multidisciplinary care to manage their complex array of needs and to mini... Read More about The Care and Management of Children and Young People with Ataxia Telangiectasia Provided by Nurses and Allied Health Professionals: a Scoping Review.

Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models (2023)
Journal Article
Liao, W., Coupland, C., Burchardt, J., Baldwin, D. R., Gleeson, F. V., Hippisley-Cox, J., & DART initiative. (2023). Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models. Lancet Respiratory Medicine, https://doi.org/10.1016/S2213-2600%2823%2900050-4

Background: Lung cancer is the second most common cancer in incidence and the leading cause of cancer deaths worldwide. Meanwhile, lung cancer screening with low-dose CT can reduce mortality. The UK National Screening Committee recommended targeted l... Read More about Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models.

How a thrombectomy service can reduce hospital deficit: a cost-effectiveness study (2022)
Journal Article
Grunwald, I. Q., Wagner, V., Podlasek, A., Koduri, G., Guyler, P., Gerry, S., Shah, S., Sievert, H., Sharma, A., Mathur, S., Fassbender, K., Shariat, K., Houston, G., Kanodia, A., & Walter, S. (2022). How a thrombectomy service can reduce hospital deficit: a cost-effectiveness study. Cost Effectiveness and Resource Allocation, 20(1), Article 59. https://doi.org/10.1186/s12962-022-00395-8

Background: There is level 1 evidence for cerebral thrombectomy with thrombolysis in acute large vessel occlusion. Many hospitals are now contemplating setting up this life-saving service. For the hospital, however, the first treatment is associated... Read More about How a thrombectomy service can reduce hospital deficit: a cost-effectiveness study.

Incidence and prevalence of venous thromboembolism in chronic liver disease: A systematic review and meta-analysis (2022)
Journal Article
Subhani, M., Sheth, A., Ahmed, J., Wijayasiri, P., Gardezi, S. A., Enki, D., Morling, J. R., Aithal, G. P., Ryder, S. D., & Aravinthan, A. D. (2022). Incidence and prevalence of venous thromboembolism in chronic liver disease: A systematic review and meta-analysis. Thrombosis Research, 215, 19-29. https://doi.org/10.1016/j.thromres.2022.05.004

Background and Aims: Historically, bleeding was thought to be a frequent and fatal complication of liver disease. However, thrombosis due to coagulation disorders in cirrhosis remains a real risk. We aim to systematically analyse published articles t... Read More about Incidence and prevalence of venous thromboembolism in chronic liver disease: A systematic review and meta-analysis.

The natural history of ataxia-telangiectasia (A-T): A systematic review (2022)
Journal Article
Petley, E., Yule, A., Alexander, S., Ojha, S., & Whitehouse, W. P. (2022). The natural history of ataxia-telangiectasia (A-T): A systematic review. PLoS ONE, 17(3), Article e0264177. https://doi.org/10.1371/journal.pone.0264177

Background: Ataxia-telangiectasia is an autosomal recessive, multi-system, and life-shortening disease caused by mutations in the ataxia-telangiectasia mutated gene. Although widely reported, there are no studies that give a comprehensive picture of... Read More about The natural history of ataxia-telangiectasia (A-T): A systematic review.

Overview of Noninterpretive Artificial Intelligence Models for Safety, Quality, Workflow, and Education Applications in Radiology Practice (2022)
Journal Article
Tadavarthi, Y., Makeeva, V., Wagstaff, W., Zhan, H., Podlasek, A., Bhatia, N., Heilbrun, M., Krupinski, E., Safdar, N., Banerjee, I., Gichoya, J., & Trivedi, H. (2022). Overview of Noninterpretive Artificial Intelligence Models for Safety, Quality, Workflow, and Education Applications in Radiology Practice. Radiology: Artificial Intelligence, 4(2), Article e210114. https://doi.org/10.1148/ryai.210114

Artificial intelligence has become a ubiquitous term in radiology over the past several years, and much attention has been given to applications that aid radiologists in the detection of abnormalities and diagnosis of diseases. However, there are man... Read More about Overview of Noninterpretive Artificial Intelligence Models for Safety, Quality, Workflow, and Education Applications in Radiology Practice.

Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content (2022)
Journal Article
Taylor, M., Simoes, F., Smith, J., Genapathy, S., Canning, A., Lledos, M., Chan, W. C., Denning, C., Scurr, D. J., Steven, R. T., Spencer, S. J., Shard, A. G., Alexander, M. R., & Zelzer, M. (2022). Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content. Surface and Interface Analysis, 54(4), 417-432. https://doi.org/10.1002/sia.7052

Peptide-coated surfaces are widely employed in biomaterial design, but quantifiable correlation between surface composition and biological response is challenging due to, for example, instrumental limitations, a lack of suitable model surfaces or lim... Read More about Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content.