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Biological characteristics and clinical outcome of triple negative primary breast cancer in older women - comparison with their younger counterparts.

Syed, Binafsha M.; Green, Andrew R.; Nolan, Christopher C.; Morgan, David A.L.; Ellis, Ian O.; Cheung, Kwok-Leung

Biological characteristics and clinical outcome of triple negative primary breast cancer in older women - comparison with their younger counterparts. Thumbnail


Authors

Binafsha M. Syed

Christopher C. Nolan

David A.L. Morgan

Ian O. Ellis



Abstract

Triple negative (ER, PgR and HER2 negative) breast cancers (TNBCs) are often considered as a poor prognostic phenotype. There is dearth of evidence showing the prevalence and biological behaviour of TNBCs in older women. This study aimed to analyse their biological characteristics in comparison with a well characterised younger series from a single centre with long term clinical follow-up. Over 37 years (1973–2010), 1,758 older (≥70 years) women with early operable (

Journal Article Type Article
Acceptance Date May 26, 2014
Publication Date Jul 7, 2014
Deposit Date Sep 7, 2018
Publicly Available Date Oct 18, 2018
Journal PLoS ONE
Electronic ISSN 1932-6203
Publisher Public Library of Science
Peer Reviewed Peer Reviewed
Volume 9
Issue 7
Article Number e10057
DOI https://doi.org/10.1371/journal.pone.0100573
Public URL https://nottingham-repository.worktribe.com/output/1098192
Publisher URL https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100573
PMID 24999743
Additional Information eStaffProfile Description: , eStaffProfile Brief Description of Type:

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