Skip to main content

Research Repository

Advanced Search

Bismuth(V)-Mediated C–H Arylation of Phenols and Naphthols

Senior, Aaron; Ball, Liam T.

Bismuth(V)-Mediated C–H Arylation of Phenols and Naphthols Thumbnail


Authors

Aaron Senior

Profile Image

LIAM BALL Liam.Ball@nottingham.ac.uk
Associate Professor



Abstract

We recently reported a general and practical strategy for the Bi(V)-mediated C–H arylation of phenols and naphthols. Our telescoped protocol proceeds via transmetallation from readily available arylboronic acids to a stable Bi(III) precursor, oxidation to a reactive Bi(V) intermediate, and subsequent ortho-selective phenol arylation. The process exhibits broad scope with respect to both components and tolerates functionality that is incompatible with conventional cross-coupling methods. Preliminary investigations provide insight into the mechanism of each key reaction step.

Journal Article Type Article
Acceptance Date Aug 18, 2020
Online Publication Date Sep 28, 2020
Publication Date 2021-02
Deposit Date Jun 25, 2021
Publicly Available Date Sep 29, 2021
Journal Synlett
Print ISSN 0936-5214
Electronic ISSN 1437-2096
Publisher Thieme Publishing
Peer Reviewed Peer Reviewed
Volume 32
Issue 03
Pages 235-240
DOI https://doi.org/10.1055/s-0040-1706294
Keywords Organic Chemistry
Public URL https://nottingham-repository.worktribe.com/output/4939468
Publisher URL https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0040-1706294

Files





You might also like



Downloadable Citations