All Outputs (1578)

Pilot and quantitative evaluation of the TARGET acne toolkit by UK pharmacy professionals working in general practice (2024)
Journal Article

Background: Acne vulgaris (acne) is a common skin condition sometimes needing topical or oral antibiotic treatment. Pharmacists and pharmacy technicians (together known as pharmacy professionals) working in general practice are well placed to ensure... Read More about Pilot and quantitative evaluation of the TARGET acne toolkit by UK pharmacy professionals working in general practice.

ZIF-67 grown onto three-dimensional biomass cotton fibers for efficient adsorption of tetracycline (2024)
Journal Article

In recent years, Metal-Organic Frameworks (MOFs) have garnered significant attention for their potential in tetracycline (TC) removal. However, pure MOFs typically exist in powdered form and tend to aggregate in water, which greatly limits practical... Read More about ZIF-67 grown onto three-dimensional biomass cotton fibers for efficient adsorption of tetracycline.

Trans and non‐binary person‐centred therapists' experiences of, and responses to, transprejudice from clients: A reflexive thematic analysis (2024)
Journal Article

Aims: This qualitative study aimed to explore what it is like for trans and non‐binary (TNB) person‐centred therapists to be exposed to transprejudice in their client work, and how they navigate such relationships. In so doing, the study aims to ampl... Read More about Trans and non‐binary person‐centred therapists' experiences of, and responses to, transprejudice from clients: A reflexive thematic analysis.

The effectiveness of digital interventions for self-management of chronic pain in employment settings: a systematic review (2024)
Journal Article

Introduction Chronic pain affects over a quarter of the workforce with high economic burden for individuals, employers, and healthcare services. Access to work-related advice for people with chronic pain is variable. This systematic review aims to... Read More about The effectiveness of digital interventions for self-management of chronic pain in employment settings: a systematic review.

Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals (2024)
Journal Article

The segregation of glycosylphosphatidylinositol-anchored proteins (GPI-APs) to distinct domains on the plasma membrane of eukaryotic cells is important for their correct cellular function, but the mechanisms by which GPI-APs are sorted are yet to be... Read More about Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals.

Real-time Bayesian Inversion in Resin Transfer Moulding using Neural Surrogates (2024)
Journal Article

In Resin Transfer Moulding (RTM), local variations in reinforcement properties (porosity and permeabil-ity) and the formation of gaps along the reinforcement edges result in non-uniform resin flow patterns, which may cause defects in the produced com... Read More about Real-time Bayesian Inversion in Resin Transfer Moulding using Neural Surrogates.

Impact of patient demographics on treatment outcomes in AML: a population-based registry in England, 2013-2020 (2024)
Journal Article

We report 1- and 5-year survival following AML diagnosis and early mortality, within 30 days of systemic anti-cancer therapy (SACT) treatments, using national cancer registry data in England. Patients aged 18-99 years diagnosed between 2013 and 2... Read More about Impact of patient demographics on treatment outcomes in AML: a population-based registry in England, 2013-2020.

Maternity support workers’ experiences of workplace trauma and post-traumatic stress symptoms (2024)
Journal Article

Background Maternity support workers (MSWs) are now a key part of the maternity workforce. They work in environments with potential exposure to traumatic events, but little is known about their rates of exposure or... Read More about Maternity support workers’ experiences of workplace trauma and post-traumatic stress symptoms.

Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension (2024)
Journal Article

Herein, a series of novel arylpiperazine (piperidine) derivatives were designed, synthesized, and evaluated for mechanisms of action through in vitro and in vivo studies. The most promising compound, II-13 (later named as MT-1207), is a potent α1 and... Read More about Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension.

Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance (2024)
Journal Article

Domestic combustion emissions pose a growing risk to public health, especially in the UK. Existing responses are polarised, with government advocating use of lower emission fuels and stoves while clean air campaigners call for blanket bans on burning... Read More about Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance.

Redox Materials for Electrochemical Capacitors (2024)
Journal Article

Electrochemical capacitors are known for their high power density and cyclability, and various redox reactions can be utilized to improve their energy density. A great variety of redox materials have been investigated recently for use in electrochemi... Read More about Redox Materials for Electrochemical Capacitors.

Researching the everyday educational lives of low-income families: the importance of researcher and participant contexts (2024)
Journal Article

This paper highlights the importance of considering both researcher and participant contexts when exploring everyday educational lives. It emerges during a period of increasing and sustained social inequality in England, and against a backdrop of inc... Read More about Researching the everyday educational lives of low-income families: the importance of researcher and participant contexts.

Life cycle assessment of pavement construction: A case study (2024)
Journal Article

Road construction is often associated with carbon emissions from direct and indirect sources, primarily due to construction and maintenance activities. Currently, there is a lack of comprehensive Life Cycle Assessment (LCA) benchmarks to evaluate fle... Read More about Life cycle assessment of pavement construction: A case study.

Surviving by storytelling – a research through design exploration of online poetry and mental health workshops (2024)
Journal Article

Background The paper explores an online poetry and mental health project titled ‘Surviving by Storytelling’. The paper reflects on the knowledge which has been iteratively generated during the project and considers the unique challenges to deliverin... Read More about Surviving by storytelling – a research through design exploration of online poetry and mental health workshops.

Cellular and microenvironmental cues that promote macrophage fusion and foreign body response (2024)
Journal Article

During the foreign body response (FBR), macrophages fuse to form foreign body giant cells (FBGCs). Modulation of FBGC formation can prevent biomaterial degradation and loss of therapeutic efficacy. However, the microenvironmental cues that dictate FB... Read More about Cellular and microenvironmental cues that promote macrophage fusion and foreign body response.

Bond behaviour of prestressed basalt textile reinforced concrete (2024)
Journal Article

Innovative Textile Reinforced Concrete (TRC) composites, although holding a significant potential, usually have poor performance under serviceability conditions. Addressing this limitation requires applying innovative techniques, such as prestressing... Read More about Bond behaviour of prestressed basalt textile reinforced concrete.

How does viewing angle affect the perceived accuracy of Batesian mimicry in hoverflies? (2024)
Journal Article

Despite Batesian mimicry often eliciting predator avoidance, many Batesian mimics, such as some species of hoverfly (Syrphidae), are considered to have an “imperfect” resemblance to their model. One possible explanation for the persistence of apparen... Read More about How does viewing angle affect the perceived accuracy of Batesian mimicry in hoverflies?.

Exposure to blue light reduces antimicrobial resistant Pseudomonas aeruginosa isolated from dog ear infections (2024)
Journal Article

Introduction: Pseudomonas aeruginosa is a leading cause of canine otitis externa. Enrofloxacin is often applied topically to treat this condition, although recalcitrant and recurring infections are common. There is evidence that exposure to blue ligh... Read More about Exposure to blue light reduces antimicrobial resistant Pseudomonas aeruginosa isolated from dog ear infections.

Policy Brief: Autism and Suicide Prevention (2024)
Report

More than one in 100 people in the UK are autistic. Yet, autistic people are not always supported, or accepted, by society. There is a considerably increased risk of suicide in autistic people compared to non-autistic people. Suicide rates in t... Read More about Policy Brief: Autism and Suicide Prevention.

Local learning landscapes: conceptualising place-based professional learning by teachers and schools in decentralised education systems (2024)
Journal Article

This article sets out an original conceptual framework for place-based professional learning by teachers and schools in decentralised education systems. High quality Continuing Professional Development and Learning (CDPL) by teachers is associated wi... Read More about Local learning landscapes: conceptualising place-based professional learning by teachers and schools in decentralised education systems.