Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation
(2014)
Journal Article
A concise synthesis of the biologically active alkaloid berberine is reported, and a versatile palladium?catalyzed enolate arylation is used to form the isoquinoline core. The overall yield of 50?% is a large improvement over the single, previous syn... Read More about Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation.