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Prof MICHAEL CHAPPELL's Outputs (6)

A general framework for optimizing arterial spin labeling MRI experiments (2018)
Journal Article
Woods, J. G., Chappell, M. A., & Okell, T. W. (2019). A general framework for optimizing arterial spin labeling MRI experiments. Magnetic Resonance in Medicine, 81(4), 2474-2488. https://doi.org/10.1002/mrm.27580

Purpose
Arterial spin labeling (ASL) MRI is a non‐invasive perfusion imaging technique that is inherently SNR limited, so scan protocols ideally need to be rigorously optimized to provide the most accurate measurements. A general framework is presen... Read More about A general framework for optimizing arterial spin labeling MRI experiments.

Assessing Reliability of Myocardial Blood Flow After Motion Correction With Dynamic PET Using a Bayesian Framework (2018)
Journal Article
Saillant, A., Armstrong, I., Shah, V., Zuehlsdorff, S., Hayden, C., Declerck, J., …Chappell, M. A. (2019). Assessing Reliability of Myocardial Blood Flow After Motion Correction With Dynamic PET Using a Bayesian Framework. IEEE Transactions on Medical Imaging, 38(5), 1216-1226. https://doi.org/10.1109/tmi.2018.2881992

The estimation of myocardial blood flow (MBF) in dynamic PET can be biased by many different processes. A major source of error, particularly in clinical applications, is patient motion. Patient motion, or gross motion, creates displacements between... Read More about Assessing Reliability of Myocardial Blood Flow After Motion Correction With Dynamic PET Using a Bayesian Framework.

Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice (2018)
Journal Article
Buck, J., Larkin, J. R., Simard, M. A., Khrapitchev, A. A., Chappell, M. A., & Sibson, N. R. (2018). Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice. Contrast Media and Molecular Imaging, 2018, 1-11. https://doi.org/10.1155/2018/4580919

Brain and tumour blood flow can be measured noninvasively using arterial spin labelling (ASL) magnetic resonance imaging (MRI), but reliable quantification in mouse models remains difficult. Pseudocontinuous ASL (pCASL) is recommended as the clinical... Read More about Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice.

Using arterial spin labelling to investigate spontaneous and evoked ongoing musculoskeletal pain (2018)
Other
Wartolowska, K. A., Bulte, D. P., Chappell, M. A., Jenkinson, M., Okell, T. W., Webster, M. A., & Carr, A. J. (2018). Using arterial spin labelling to investigate spontaneous and evoked ongoing musculoskeletal pain

Clinical pain is difficult to study using standard Blood Oxy-genation Level Dependent (BOLD) magnetic resonance imaging because it is often ongoing and, if evoked, it is associated with stimulus-correlated motion. Arterial spin labelling (ASL) offers... Read More about Using arterial spin labelling to investigate spontaneous and evoked ongoing musculoskeletal pain.