Professor DILEEP LOBO's Outputs (5)

The pathophysiology of fluid and electrolyte balance in the older adult surgical patient (2013)
Journal Article
El-Sharkawy, A. M., Sahota, O., Maughan, R. J., & Lobo, D. N. (2013). The pathophysiology of fluid and electrolyte balance in the older adult surgical patient. Clinical Nutrition, 33(1), https://doi.org/10.1016/j.clnu.2013.11.010

Background & aims:

Age-related physiological changes predispose even the healthy older adult to fluid and electrolyte abnormalities which can cause morbidity and mortality. The aim of this narrative review is to highlight key aspects of age-relat... Read More about The pathophysiology of fluid and electrolyte balance in the older adult surgical patient.

The presence of tumour-associated lymphocytes confers a good prognosis in pancreatic ductal adenocarcinoma: an immunohistochemical study of tissue microarrays (2013)
Journal Article
Tewari, N., Zaitoun, A. M., Arora, A., Madhusudan, S., Ilyas, M., & Lobo, D. N. (2013). The presence of tumour-associated lymphocytes confers a good prognosis in pancreatic ductal adenocarcinoma: an immunohistochemical study of tissue microarrays. BMC Cancer, 13, Article 436. https://doi.org/10.1186/1471-2407-13-436

Background
Tumour-associated lymphocytes (TALs) have been linked with good prognosis in several solid tumours. This study aimed to evaluate the prognostic significance of CD3, CD8 and CD20 positive lymphocytes in pancreatic ductal adenocarcinoma.... Read More about The presence of tumour-associated lymphocytes confers a good prognosis in pancreatic ductal adenocarcinoma: an immunohistochemical study of tissue microarrays.

Are DNA repair factors promising biomarkers for personalized therapy in gastric cancer? (2013)
Journal Article
Abdel-Fatah, T., Arora, A., Gorguc, I., Abbotts, R., Beebeejaun, S., Storr, S. J., Mohan, V., Hawkes, C., Soomro, I. N., Lobo, D. N., Parsons, S. L., & Madhusudan, S. (2013). Are DNA repair factors promising biomarkers for personalized therapy in gastric cancer?. Antioxidants and Redox Signaling, 18(18), https://doi.org/10.1089/ars.2012.4873

Chronic inflammation is a driving force for gastric carcinogenesis. Reactive oxygen species (ROS) generated during the inflammatory process generates DNA damage that is processed through the DNA repair pathways. In this study, we profiled key DNA rep... Read More about Are DNA repair factors promising biomarkers for personalized therapy in gastric cancer?.

Intestinal ischemia following laparoscopic surgery: a case series (2013)
Journal Article
Al-Khyatt, W., Thomas, J. D., Humes, D. J., & Lobo, D. N. (2013). Intestinal ischemia following laparoscopic surgery: a case series. Journal of Medical Case Reports, 7(25), Article 25. https://doi.org/10.1186/1752-1947-7-25

Introduction: Intestinal ischemia is a rare complication of laparoscopic surgery. Its prognosis depends on a high
index of suspicion and effective early treatment.
Case presentation: In the present report, we describe three cases where intestinal i... Read More about Intestinal ischemia following laparoscopic surgery: a case series.

Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas (2013)
Journal Article
Storr, S. J., Pu, X., Davis, J., Lobo, D., Reece-Smith, A. M., Parsons, S. L., Madhusudan, S., & Martin, S. G. (2013). Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas. Journal of Gastroenterology, 48(11), 1213-1221. https://doi.org/10.1007/s00535-012-0743-4