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Policy Brief: Access to care for neurodiversity - ADHD and Tourette Syndrome (2024)
Report
French, B., & Groom, M. (2024). Policy Brief: Access to care for neurodiversity - ADHD and Tourette Syndrome. University of Nottingham

Around 15-20% of the population is neurodivergent. Despite this, access to diagnoses and care for neurodivergent people is problematic and there is inconsistent support across the UK. Research at the University of Nottingham focuses on the impor... Read More about Policy Brief: Access to care for neurodiversity - ADHD and Tourette Syndrome.

The impacts associated with having ADHD: an umbrella review (2024)
Journal Article
French, B., Nalbant, G., Wright, H., Sayal, K., Daley, D., Groom, M. J., …Hall, C. L. (2024). The impacts associated with having ADHD: an umbrella review. Frontiers in Psychiatry, 15, Article 1343314. https://doi.org/10.3389/fpsyt.2024.1343314

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) affects up to 5% of the population and is characterised by symptoms of impulsivity, hyperactivity and inattention. These symptoms are significantly impairing and carry additional risks for... Read More about The impacts associated with having ADHD: an umbrella review.

Associations of physical activity and cardiorespiratory fitness with cognitive function, self-control, and resilience in young people with attention deficit hyperactivity disorder (2024)
Journal Article
Sibbick, E., Boat, R., Sarkar, M., Johnston, J. P., Groom, M., Williams, R. A., …Cooper, S. B. (2024). Associations of physical activity and cardiorespiratory fitness with cognitive function, self-control, and resilience in young people with attention deficit hyperactivity disorder. Advanced Exercise and Health Science, 1(1), 51-58. https://doi.org/10.1016/j.aehs.2024.01.003

The aim of the present study was to investigate if physical activity and cardiorespiratory fitness influence cognition, self-control, and resilience in young people with ADHD. Fifty-four children with ADHD (12.8 ± 1.4 y) completed questionnaires to a... Read More about Associations of physical activity and cardiorespiratory fitness with cognitive function, self-control, and resilience in young people with attention deficit hyperactivity disorder.

Social anxiety is more likely to influence reputation management decisions than autistic traits (2023)
Journal Article
Dubey, I., Groom, M., Tahir, A., & Hamilton, A. (2024). Social anxiety is more likely to influence reputation management decisions than autistic traits. Autism Research, 17(1), 78-88. https://doi.org/10.1002/aur.3040

People manage their social reputation by selectively sharing achievements, thereby shaping the way others think about them. Autistic traits and social anxiety may have opposing impacts on reputation management. This study aimed to identify the influe... Read More about Social anxiety is more likely to influence reputation management decisions than autistic traits.

Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis (2023)
Journal Article
Bellato, A., Hall, C. L., Groom, M. J., Simonoff, E., Thapar, A., Hollis, C., & Cortese, S. (2024). Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis. Journal of Child Psychology and Psychiatry, 65(6), 845-861. https://doi.org/10.1111/jcpp.13901

Background Several computerised cognitive tests (e.g. continuous performance test) have been developed to support the clinical assessment of attention-deficit/hyperactivity disorder (ADHD). Here, we appraised the evidence-base underpinning the use o... Read More about Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis.

Patients’ experience of accessing support for tics from primary care in the UK: an online mixed-methods survey (2023)
Journal Article
Marino, C., Khan, K., Groom, M. J., Hall, S. S., Anderson, S., Mcnally, E., …Hall, C. L. (2023). Patients’ experience of accessing support for tics from primary care in the UK: an online mixed-methods survey. BMC Health Services Research, 23, Article 788. https://doi.org/10.1186/s12913-023-09753-5

Background Tics are common in children and young people and may persist into adulthood. Tics can cause challenges with social, occupational, physical, and academic functioning. The current study explores the perceptions of adults with tics and paren... Read More about Patients’ experience of accessing support for tics from primary care in the UK: an online mixed-methods survey.

Relationship between autonomic arousal and attention orienting in children and adolescents with ADHD, autism and co-occurring ADHD and autism (2023)
Journal Article
Bellato, A., Arora, I., Kochhar, P., Ropar, D., Hollis, C., & Groom, M. J. (2023). Relationship between autonomic arousal and attention orienting in children and adolescents with ADHD, autism and co-occurring ADHD and autism. Cortex, 166, 306-321. https://doi.org/10.1016/j.cortex.2023.06.002

Introduction Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) may be characterized by different profiles of visual attention orienting. However, there are also many inconsistent findings emerging from the literature... Read More about Relationship between autonomic arousal and attention orienting in children and adolescents with ADHD, autism and co-occurring ADHD and autism.

Risks Associated With Undiagnosed ADHD and/or Autism: A Mixed-Method Systematic Review (2023)
Journal Article
French, B., Daley, D., Groom, M., & Cassidy, S. (2023). Risks Associated With Undiagnosed ADHD and/or Autism: A Mixed-Method Systematic Review. Journal of Attention Disorders, 27(12), 1393-1410. https://doi.org/10.1177/10870547231176862

Background: The two most prevalent neurodevelopmental disorders—Attention Deficit Hyperactivity Disorder (ADHD) and Autism (ASD)—(ASD/ADHD) strongly impact individuals’ functions. This is worsened when individuals are undiagnosed and risks such as in... Read More about Risks Associated With Undiagnosed ADHD and/or Autism: A Mixed-Method Systematic Review.

Remote administration of ADHD-sensitive cognitive tasks: a pilot study (2023)
Journal Article
Sun, S., Denyer, H., Sankesara, H., Deng, Q., Ranjan, Y., Conde, P., …Kuntsi, J. (2023). Remote administration of ADHD-sensitive cognitive tasks: a pilot study. Journal of Attention Disorders, 27(9), 1040-1050. https://doi.org/10.1177/10870547231172

Objective: We assessed the feasibility and validity of remote researcher-led administration and self-administration of modified versions of two cognitive tasks sensitive to ADHD, a four-choice reaction time task (Fast task) and a combined Continuous... Read More about Remote administration of ADHD-sensitive cognitive tasks: a pilot study.

We need timely access to mental health data: implications of the Goldacre review (2023)
Journal Article
Astle, D. E., Moore, A., Marryat, L., Viding, E., Mansfield, K. L., Fazel, M., …Ford, T. J. (2023). We need timely access to mental health data: implications of the Goldacre review. Lancet Psychiatry, 10(4), 242-244. https://doi.org/10.1016/S2215-0366%2823%2900030-5

The Goldacre review, published in April, 2022, 1 is a landmark evaluation of the use, availability, and safety of National Health Service (NHS) data across all four nations of the UK. The review underscores the necessary role of data in driving healt... Read More about We need timely access to mental health data: implications of the Goldacre review.

Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol (2023)
Presentation / Conference Contribution
Stein, A., Iyer, K., Dux, P., Friehs, M., Riddle, J., Craven, M., …Barlow, K. (2023, February). Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol. Poster presented at 5th International Brain Stimulation Conference, Lisbon, Portugal

Introduction: Traumatic brain injury (TBI) is the most common acquired brain injury (ABI), where 16% of children sustain at least one TBI requiring medical attention, and 25-30% experience chronic problems. Attention and concentration problems are am... Read More about Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol.

Distance learning during the COVID-19 pandemic for children with ADHD and/or ASD: a European multi-center study examining the role of executive function deficits and age (2022)
Journal Article
Thorell, L. B., Fuermaier, A. B. M., Christiansen, H., Steinmayr, R., Baeyens, D., de la Peña, A. G., …Skoglund, C. (2022). Distance learning during the COVID-19 pandemic for children with ADHD and/or ASD: a European multi-center study examining the role of executive function deficits and age. Child and Adolescent Psychiatry and Mental Health, 16(1), Article 101. https://doi.org/10.1186/s13034-022-00540-4

Background: One of the COVID-19 pandemic consequences that has affected families the most is school lockdowns. Some studies have shown that distance learning has been especially challenging for families with a child with neurodevelopmental disorders... Read More about Distance learning during the COVID-19 pandemic for children with ADHD and/or ASD: a European multi-center study examining the role of executive function deficits and age.

The effects of stimulant and non-stimulant medications on the autonomic nervous system (ANS) functioning in people with ADHD: A systematic review and meta-analysis (2022)
Journal Article
Idrees, I., Bellato, A., Cortese, S., & Groom, M. J. (2023). The effects of stimulant and non-stimulant medications on the autonomic nervous system (ANS) functioning in people with ADHD: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews, 144, Article 104968. https://doi.org/10.1016/j.neubiorev.2022.104968

We carried out a systematic review and meta-analysis to investigate the effects of stimulant and non-stimulant medications on autonomic functioning in people with ADHD (PROSPERO: CRD42020212439). We searched (9th August 2021) PsycInfo, MEDLINE, EMBAS... Read More about The effects of stimulant and non-stimulant medications on the autonomic nervous system (ANS) functioning in people with ADHD: A systematic review and meta-analysis.

Acute effects of physical activity on cognitive function in children and adolescents with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis (2022)
Journal Article
Sibbick, E., Boat, R., Sarkar, M., Groom, M., & Cooper, S. B. (2022). Acute effects of physical activity on cognitive function in children and adolescents with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis. Mental Health and Physical Activity, 23, Article 100469. https://doi.org/10.1016/j.mhpa.2022.100469

Attention-deficit/hyperactivity disorder (ADHD), one of the most common neurodevelopmental disorders in children and adolescents, is typically managed with medications which are associated with negative side effects. Therefore, non-pharmacological tr... Read More about Acute effects of physical activity on cognitive function in children and adolescents with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis.

Current Pharmacological Treatments for ADHD (2022)
Book Chapter
Groom, M. J., & Cortese, S. (2022). Current Pharmacological Treatments for ADHD. In New Discoveries in the Behavioral Neuroscience of Attention-Deficit Hyperactivity Disorder (19-50). Springer. https://doi.org/10.1007/7854_2022_330

Attention-Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental condition associated with impaired function and increased risk of poor outcomes in children, young people and adults with the condition. Currently approved pharmacologi... Read More about Current Pharmacological Treatments for ADHD.

The feasibility of a strategy for the remote recruitment, consenting and assessment of recent referrals: a protocol for phase 1 of the On-Line Parent Training for the Initial Management of ADHD referrals (OPTIMA) (2022)
Journal Article
Kostyrka-Allchorne, K., Ballard, C., Byford, S., Cortese, S., Daley, D., Downs, J., …Sonuga-Barke, E. J. (2022). The feasibility of a strategy for the remote recruitment, consenting and assessment of recent referrals: a protocol for phase 1 of the On-Line Parent Training for the Initial Management of ADHD referrals (OPTIMA). Pilot and Feasibility Studies, 8(1), 1-14. https://doi.org/10.1186/s40814-021-00959-0

Background: In the UK, children with high levels of hyperactivity, impulsivity and inattention referred to clinical services with possible attention-deficit/hyperactivity disorder (ADHD) often wait a long time for specialist diagnostic assessment. Pa... Read More about The feasibility of a strategy for the remote recruitment, consenting and assessment of recent referrals: a protocol for phase 1 of the On-Line Parent Training for the Initial Management of ADHD referrals (OPTIMA).

A comparison of simultaneous and sequential visuo-spatial memory in children born very preterm (2021)
Journal Article
Retzler, J., Johnson, S., Groom, M. J., & Cragg, L. (2021). A comparison of simultaneous and sequential visuo-spatial memory in children born very preterm. Child Neuropsychology, 28(4), 496-509. https://doi.org/10.1080/09297049.2021.1993808

Research suggests that children born very preterm (≤32weeks’ gestation) are at greater risk of impairments in information processing (particularly when information is presented simultaneously rather than sequentially) and visuo-spatial short-term and... Read More about A comparison of simultaneous and sequential visuo-spatial memory in children born very preterm.

Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions (2021)
Journal Article
Bellato, A., Arora, I., Kochhar, P., Ropar, D., Hollis, C., & Groom, M. J. (2022). Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions. Journal of Autism and Developmental Disorders, 52, 4679-4691. https://doi.org/10.1007/s10803-021-05244-w

Despite overlaps in clinical symptomatology, autism and ADHD may be associated with opposite autonomic arousal profiles which might partly explain altered cognitive and global functioning. We investigated autonomic arousal in 106 children/adolescents... Read More about Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions.

A systematic review and meta-analysis of altered electrophysiological markers of performance monitoring in Obsessive-Compulsive Disorder (OCD), Gilles de la Tourette Syndrome (GTS), Attention-Deficit/Hyperactivity disorder (ADHD) and Autism (2021)
Journal Article
Bellato, A., Norman, L., Idrees, I., Ogawa, C. Y., Waitt, A., Zuccolo, P. F., …Shephard, E. (2021). A systematic review and meta-analysis of altered electrophysiological markers of performance monitoring in Obsessive-Compulsive Disorder (OCD), Gilles de la Tourette Syndrome (GTS), Attention-Deficit/Hyperactivity disorder (ADHD) and Autism. Neuroscience and Biobehavioral Reviews, 131, 964-987. https://doi.org/10.1016/j.neubiorev.2021.10.018

Altered performance monitoring is implicated in obsessive-compulsive disorder (OCD), Gilles de la Tourette syndrome (GTS), attention-deficit/hyperactivity disorder (ADHD) and autism. We conducted a systematic review and meta-analysis of electrophysio... Read More about A systematic review and meta-analysis of altered electrophysiological markers of performance monitoring in Obsessive-Compulsive Disorder (OCD), Gilles de la Tourette Syndrome (GTS), Attention-Deficit/Hyperactivity disorder (ADHD) and Autism.

Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., …Groom, M. J. (2021). Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 94. https://doi.org/10.1186/s40814-021-00830-2

What is the Effect of Stimulus Complexity on Attention to Repeating and Changing Information in Autism? (2021)
Journal Article
Arora, I., Bellato, A., Gliga, T., Ropar, D., Kochhar, P., Hollis, C., & Groom, M. (2022). What is the Effect of Stimulus Complexity on Attention to Repeating and Changing Information in Autism?. Journal of Autism and Developmental Disorders, 52(2), 600–616. https://doi.org/10.1007/s10803-021-04961-6

Slower habituation to repeating stimuli characterises Autism, but it is not known whether this is driven by difficulties with information processing or an attentional bias towards sameness. We conducted eye-tracking and presented looming geometrical... Read More about What is the Effect of Stimulus Complexity on Attention to Repeating and Changing Information in Autism?.

Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., …Groom, M. J. (2021). Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 68. https://doi.org/10.1186/s40814-021-00788-1

Background Medication for attention deficit hyperactivity disorder (ADHD) should be closely monitored to ensure optimisation. There is growing interest in using computerised assessments of ADHD symptoms to support medication monitoring. The aim of t... Read More about Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial.

Is autonomic function during resting-state atypical in Autism: A systematic review of evidence (2021)
Journal Article
Arora, I., Bellato, A., Ropar, D., Hollis, C., & Groom, M. (2021). Is autonomic function during resting-state atypical in Autism: A systematic review of evidence. Neuroscience and Biobehavioral Reviews, 125, 417-441. https://doi.org/10.1016/j.neubiorev.2021.02.041

Background: Theories of differences in resting-state arousal in autistic individuals are influential. Differences in arousal during resting-state would impact engagement and adaptation to the environment, having a cascading effect on development of a... Read More about Is autonomic function during resting-state atypical in Autism: A systematic review of evidence.

The implementation of telehealth to assess, monitor and treat neurodevelopmental disorders: a systematic review (2021)
Journal Article
Valentine, A. Z., Hall, S. S., Young, E., Brown, B. J., Groom, M. J., Hollis, C., & Hall, C. L. (2021). The implementation of telehealth to assess, monitor and treat neurodevelopmental disorders: a systematic review. Journal of Medical Internet Research, 23(1), Article e22619. https://doi.org/10.2196/22619

Background: In response to COVID-19 there is increasing momentum behind the development and delivery of telehealth. To assess the anticipated exponential growth in telehealth it is important we accurately capture how telehealth was used in specific f... Read More about The implementation of telehealth to assess, monitor and treat neurodevelopmental disorders: a systematic review.

Parental experiences of homeschooling during the COVID-19 pandemic: differences between seven European countries and between children with and without mental health conditions (2021)
Journal Article
Thorell, L. B., Borg Skoglund, C., Giménez de la Peña, A., Baeyens, D., Fuermaier, A. B., Groom, M. J., …Christiansen, H. (2022). Parental experiences of homeschooling during the COVID-19 pandemic: differences between seven European countries and between children with and without mental health conditions. European Child and Adolescent Psychiatry, 31, 649-661. https://doi.org/10.1007/s00787-020-01706-1

The aim of the present study was to examine parental experiences of homeschooling during the COVID-19 pandemic in families with or without a child with a mental health condition across Europe. The study included 6720 parents recruited through schools... Read More about Parental experiences of homeschooling during the COVID-19 pandemic: differences between seven European countries and between children with and without mental health conditions.

Bibliometric Review: Classroom Management in ADHD—Is There a Communication Gap Concerning Knowledge Between the Scientific Fields Psychiatry/Psychology and Education? (2020)
Journal Article
Dort, M., Strelow, A. E., French, B., Groom, M., Luman, M., Thorell, L. B., …Christiansen, H. (2020). Bibliometric Review: Classroom Management in ADHD—Is There a Communication Gap Concerning Knowledge Between the Scientific Fields Psychiatry/Psychology and Education?. Sustainability, 12(17), Article 6826. https://doi.org/10.3390/su12176826

Many students with ADHD experience educational attainment difficulties. Nevertheless, evidence-based classroom management strategies (CMS) are seldom used. This science–practitioner gap might be due to a lack of shared knowledge between the scientifi... Read More about Bibliometric Review: Classroom Management in ADHD—Is There a Communication Gap Concerning Knowledge Between the Scientific Fields Psychiatry/Psychology and Education?.

A systematic review evaluating the implementation of technologies to assess, monitor and treat neurodevelopmental disorders: A map of the current evidence (2020)
Journal Article
Valentine, A. Z., Brown, B. J., Groom, M. J., Young, E., Hollis, C., & Hall, C. L. (2020). A systematic review evaluating the implementation of technologies to assess, monitor and treat neurodevelopmental disorders: A map of the current evidence. Clinical Psychology Review, 80, 101870. https://doi.org/10.1016/j.cpr.2020.101870

Technology-based interventions provide an attractive option for improving service provision for neurodevelopmental disorders (NDD), for example, widening access to interventions, objective assessment, and monitoring; however, it is unclear whether th... Read More about A systematic review evaluating the implementation of technologies to assess, monitor and treat neurodevelopmental disorders: A map of the current evidence.

Atypical Electrophysiological Indices of Eyes-Open and Eyes-Closed Resting-State in Children and Adolescents with ADHD and Autism (2020)
Journal Article
Bellato, A., Arora, I., Kochhar, P., Hollis, C., & Groom, M. J. (2020). Atypical Electrophysiological Indices of Eyes-Open and Eyes-Closed Resting-State in Children and Adolescents with ADHD and Autism. Brain Sciences, 10(5), 1-12. https://doi.org/10.3390/brainsci10050272

Investigating electrophysiological measures during resting-state might be useful to investigate brain functioning and responsivity in individuals under diagnostic assessment for attention deficit hyperactivity disorder (ADHD) and autism. EEG was reco... Read More about Atypical Electrophysiological Indices of Eyes-Open and Eyes-Closed Resting-State in Children and Adolescents with ADHD and Autism.

Is autonomic nervous system function atypical in attention deficit hyperactivity disorder (ADHD)? A systematic review of the evidence (2019)
Journal Article
Bellato, A., Arora, I., Hollis, C., & Groom, M. J. (2020). Is autonomic nervous system function atypical in attention deficit hyperactivity disorder (ADHD)? A systematic review of the evidence. Neuroscience and Biobehavioral Reviews, 108, 182-206. https://doi.org/10.1016/j.neubiorev.2019.11.001

Although arousal mechanisms have frequently been found to be atypical in ADHD, these findings usually emerged from indirect behavioural measures which give only a limited understanding of arousal dysregulation in this condition. To assess the hypothe... Read More about Is autonomic nervous system function atypical in attention deficit hyperactivity disorder (ADHD)? A systematic review of the evidence.

Using drift diffusion modeling to understand inattentive behavior in preterm and term-born children. (2019)
Journal Article
Retzler, J., Retzler, C., Groom, M., Johnson, S., & Cragg, L. (2020). Using drift diffusion modeling to understand inattentive behavior in preterm and term-born children. Neuropsychology, 34(1), 77-87. https://doi.org/10.1037/neu0000590

Objective: Children born very preterm are at increased risk of inattention, but it remains unclear whether the underlying processes are the same as in their term-born peers. Drift diffusion modelling (DDM) may better characterise the cognitive proces... Read More about Using drift diffusion modeling to understand inattentive behavior in preterm and term-born children..

Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence (2019)
Journal Article
Krinzinger, H., Hall, C. L., Groom, M. J., Ansari, M. T., Banaschewski, T., Buitelaar, J. K., …Liddle, E. B. (2019). Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence. Neuroscience and Biobehavioral Reviews, 107, 945-968. https://doi.org/10.1016/j.neubiorev.2019.09.023

Methylphenidate (MPH), the most common medication for children with Attention Deficit/Hyperactivity Disorder (ADHD) in many countries, is often prescribed for long periods of time. Any long-term psychotropic treatment in childhood raises concerns abo... Read More about Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence.

The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms (2019)
Journal Article
Hall, C. L., Guo, B., Valentine, A. Z., Groom, M. J., Daley, D., Sayal, K., & Hollis, C. (2019). The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms. PLoS ONE, 14(6), Article e0218518. https://doi.org/10.1371/journal.pone.0218518

Background: The Strengths and Difficulties Questionnaire (SDQ) is widely used to assess child and adolescent mental health problems. However, the factor structure of the SDQ is subject to debate and there is limited evidence investigating measurement... Read More about The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms.

Consensus workshops on the development of an ADHD medication management protocol using QbTest: developing a clinical trial protocol with multidisciplinary stakeholders (2019)
Journal Article
Hall, C. L., Brown, S., James, M., Martin, J. L., Brown, N., Selby, K., …Groom, M. J. (2019). Consensus workshops on the development of an ADHD medication management protocol using QbTest: developing a clinical trial protocol with multidisciplinary stakeholders. BMC Medical Research Methodology, 19, 1-13. https://doi.org/10.1186/s12874-019-0772-2

Background The study design and protocol that underpin a randomised controlled trial (RCT) are critical for the ultimate success of the trial. Although RCTs are considered the gold standard for research, there are multiple threats to their validity... Read More about Consensus workshops on the development of an ADHD medication management protocol using QbTest: developing a clinical trial protocol with multidisciplinary stakeholders.

Reduced Prefrontal Gyrification in Carriers of the Dopamine D4 Receptor 7-Repeat Allele With Attention Deficit/Hyperactivity Disorder: A Preliminary Report (2019)
Journal Article
Palaniyappan, L., Batty, M. J., Liddle, P. F., Liddle, E. B., Groom, M. J., Hollis, C., & Scerif, G. (2019). Reduced Prefrontal Gyrification in Carriers of the Dopamine D4 Receptor 7-Repeat Allele With Attention Deficit/Hyperactivity Disorder: A Preliminary Report. Frontiers in Psychiatry, 10, Article 235. https://doi.org/10.3389/fpsyt.2019.00235

Objective: Structural and functional abnormalities have been noted in the prefrontal cortex of individuals with neurodevelopmental disorders such as attention deficit/hyperactivity disorder (ADHD). Cortical thickness and gyrification, both of which h... Read More about Reduced Prefrontal Gyrification in Carriers of the Dopamine D4 Receptor 7-Repeat Allele With Attention Deficit/Hyperactivity Disorder: A Preliminary Report.

The Validity of the SNAP-IV in Children Displaying ADHD Symptoms (2019)
Journal Article
Hall, C. L., Guo, B., Valentine, A. Z., Groom, M. J., Daley, D., Sayal, K., & Hollis, C. (2020). The Validity of the SNAP-IV in Children Displaying ADHD Symptoms. Assessment, 27(6), 1258-1271. https://doi.org/10.1177/1073191119842255

The Swanson, Nolan, and Pelham Rating Scale (SNAP-IV) is a widely used scale that measures the core symptoms of attention deficit hyperactivity disorder (ADHD). However, there are contradictory findings regarding factor structure. Factor structure an... Read More about The Validity of the SNAP-IV in Children Displaying ADHD Symptoms.

Development of human electrophysiological brain networks (2018)
Journal Article
Briley, P. M., Liddle, E. B., Groom, M. J., Smith, H. J. F., Morris, P. G., Colclough, G. L., …Liddle, P. F. (2018). Development of human electrophysiological brain networks. Journal of Neurophysiology, 120(6), 3122-3130. https://doi.org/10.1152/jn.00293.2018

Functional activity in the human brain is intrinsically organized into independently active, connected brain regions. These networks include sensorimotor systems, as well as higher-order cognitive networks such as the default mode network (DMN), whic... Read More about Development of human electrophysiological brain networks.

Cognitive predictors of parent-rated inattention in very preterm children: The role of working memory and processing speed (2018)
Journal Article
Retzler, J., Johnson, S., Groom, M., Hollis, C., Budge, H., & Cragg, L. (2019). Cognitive predictors of parent-rated inattention in very preterm children: The role of working memory and processing speed. Child Neuropsychology, 25(5), 617-635. https://doi.org/10.1080/09297049.2018.1510908

Background: Inattention is one of the most common neurobehavioural problems following very preterm birth. Attention problems can persist into adulthood and are associated with negative socio-emotional and educational outcomes. This study aimed to det... Read More about Cognitive predictors of parent-rated inattention in very preterm children: The role of working memory and processing speed.

Visuomotor learning and unlearning in children and adolescents with tourette syndrome (2018)
Journal Article
Kim, S., Jackson, S. R., Groom, M., & Jackson, G. M. (2018). Visuomotor learning and unlearning in children and adolescents with tourette syndrome. Cortex, 109, 50-59. https://doi.org/10.1016/j.cortex.2018.08.007

Tourette syndrome (TS) is a childhood-onset neurological condition characterised by an evolving repertoire of chronic motor tics and one or more phonic tics. Tics, like habits, are inflexible and repetitive behaviours that are acquired over a period... Read More about Visuomotor learning and unlearning in children and adolescents with tourette syndrome.

Implicit sequence learning in young people with Tourette syndrome with and without co-occurring attention-deficit/hyperactivity disorder (ADHD) (2018)
Journal Article
Shephard, E., Groom, M. J., & Jackson, G. M. (2019). Implicit sequence learning in young people with Tourette syndrome with and without co-occurring attention-deficit/hyperactivity disorder (ADHD). Journal of Neuropsychology, 13(3), 529-549. https://doi.org/10.1111/jnp.12167

Impaired habit-learning has been proposed to underlie the tic symptoms of Tourette syndrome (TS). However, accounts differ in terms of how habit-learning is altered in TS, with some authors proposing habit-formation is impaired due to a deficient “ch... Read More about Implicit sequence learning in young people with Tourette syndrome with and without co-occurring attention-deficit/hyperactivity disorder (ADHD).

The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected attention deficit hyperactivity disorder: single-blind randomised controlled trial (2018)
Journal Article
the AQUA Trial Group, Hollis, C., Hall, C. L., Guo, B., James, M., Boadu, J., …Morriss, R. (2018). The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected attention deficit hyperactivity disorder: single-blind randomised controlled trial. Journal of Child Psychology and Psychiatry, 59(12), 1298-1308. https://doi.org/10.1111/jcpp.12921

© 2018 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health. Background: Diagnosis of attention deficit hyperactivity disorder (ADHD) relies on su... Read More about The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected attention deficit hyperactivity disorder: single-blind randomised controlled trial.

Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment (2018)
Journal Article
Brookes, M. J., Groom, M. J., Liuzzi, L., Hill, R. M., Smith, H. J., Briley, P. M., …Liddle, E. B. (2018). Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment. NeuroImage, 174, https://doi.org/10.1016/j.neuroimage.2018.03.008

Network connectivity is an integral feature of human brain function, and characterising its maturational trajectory is a critical step towards understanding healthy and atypical neurodevelopment. Here, we used magnetoencephalography (MEG) to investig... Read More about Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment.

Protocol investigating the clinical utility of an objective measure of attention, impulsivity and activity (QbTest) for optimising medication management in children and young people with ADHD ‘QbTest Utility for Optimising Treatment in ADHD’ (QUOTA): a feasibility randomised controlled trial (2018)
Journal Article
Hall, C. L., James, M., Brown, S., Martin, J. L., Brown, N., Selby, K., …Groom, M. J. (2018). Protocol investigating the clinical utility of an objective measure of attention, impulsivity and activity (QbTest) for optimising medication management in children and young people with ADHD ‘QbTest Utility for Optimising Treatment in ADHD’ (QUOTA): a feasibility randomised controlled trial. BMJ Open, 8(2), Article e021104. https://doi.org/10.1136/bmjopen-2017-021104

Introduction: Attention-deficit hyperactivity disorder (ADHD) is characterised by symptoms of inattention, hyperactivity and impulsivity. To improve outcomes, the National Institute for Health and Care Excellence ADHD guidelines recommend regular mon... Read More about Protocol investigating the clinical utility of an objective measure of attention, impulsivity and activity (QbTest) for optimising medication management in children and young people with ADHD ‘QbTest Utility for Optimising Treatment in ADHD’ (QUOTA): a feasibility randomised controlled trial.

Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) (2017)
Journal Article
Groom, M. J., Kochhar, P., Hamilton, A., Liddle, E. B., Simeou, M., & Hollis, C. (2017). Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). Journal of Autism and Developmental Disorders, 47(5), https://doi.org/10.1007/s10803-017-3078-4

This study investigated the neurobiological basis of comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). We compared children with ASD, ADHD or ADHD+ASD and typically developing controls (CTRL) on b... Read More about Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD).

Study of user-experience of an objective test (QbTest) to aid ADHD assessment and medication management: a multi-methods approach (2017)
Journal Article
Hall, C. L., Valentine, A., Walker, G. M., Ball, H. M., Cogger, H., Daley, D., …Hollis, C. (2017). Study of user-experience of an objective test (QbTest) to aid ADHD assessment and medication management: a multi-methods approach. BMC Psychiatry, 17, Article 66. https://doi.org/10.1186/s12888-017-1222-5

Background The diagnosis and monitoring of Attention deficit hyperactivity disorder (ADHD) typically relies on subjective reports and observations. Objective continuous performance tests (CPTs) have been incorporated into some services to support... Read More about Study of user-experience of an objective test (QbTest) to aid ADHD assessment and medication management: a multi-methods approach.

The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder (2016)
Journal Article
Groom, M. J., Young, Z., Hall, C. L., Gillott, A., & Hollis, C. (2016). The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder. Psychiatry Research, 243, https://doi.org/10.1016/j.psychres.2016.06.042

There is a clinical need for objective evidence-based measures that are sensitive and specific to ADHD when compared with other neurodevelopmental disorders. This study evaluated the incremental validity of adding an objective measure of activity and... Read More about The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder.

Practitioner review: Treatments for Tourette syndrome in children and young people: a systematic review (2016)
Journal Article
Whittington, C., Pennant, M., Kendall, T., Glazebrook, C., Trayner, P., Groom, M. J., …Hollis, C. (in press). Practitioner review: Treatments for Tourette syndrome in children and young people: a systematic review. Journal of Child Psychology and Psychiatry, 57(9), 988-1004. https://doi.org/10.1111/jcpp.12556

Background: Tourette syndrome (TS) and chronic tic disorder (CTD) affect 1–2% of children and young people, but the most effective treatment is unclear. To establish the current evidence base, we conducted a systematic review of interventions for ch... Read More about Practitioner review: Treatments for Tourette syndrome in children and young people: a systematic review.

Electrophysiological correlates of reinforcement learning in young people with Tourette syndrome with and without co-occurring ADHD symptoms (2016)
Journal Article
Shephard, E., Jackson, G. M., & Groom, M. J. (2016). Electrophysiological correlates of reinforcement learning in young people with Tourette syndrome with and without co-occurring ADHD symptoms. International Journal of Developmental Neuroscience, 51, 17-27. https://doi.org/10.1016/j.ijdevneu.2016.04.005

Altered reinforcement learning is implicated in the causes of Tourette syndrome (TS) and attention-deficit/hyperactivity disorder (ADHD). TS and ADHD frequently co-occur but how this affects reinforcement learning has not been investigated. We examin... Read More about Electrophysiological correlates of reinforcement learning in young people with Tourette syndrome with and without co-occurring ADHD symptoms.

Developing mHealth Remote Monitoring Technology for Attention Deficit Hyperactivity Disorder: A Qualitative Study Eliciting User Priorities and Needs (2016)
Journal Article
Simons, L., Valentine, A. Z., Falconer, C. J., Groom, M., Daley, D., Craven, M. P., …Hollis, C. (2016). Developing mHealth Remote Monitoring Technology for Attention Deficit Hyperactivity Disorder: A Qualitative Study Eliciting User Priorities and Needs. JMIR mHealth and uHealth, 4(1), Article e31. https://doi.org/10.2196/mhealth.5009

Background: Guidelines in the United Kingdom recommend that medication titration for attention deficit hyperactivity disorder (ADHD) should be completed within 4-6 weeks and include regular reviews. However, most clinicians think that weekly clinic c... Read More about Developing mHealth Remote Monitoring Technology for Attention Deficit Hyperactivity Disorder: A Qualitative Study Eliciting User Priorities and Needs.

Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis (2016)
Journal Article
Hollis, C., Pennant, M., Cuenca, J., Glazebrook, C., Kendall, T., Whittington, C., Stockton, S., Larsson, L., Bunton, P., Dobson, S., Groom, M. J., Hedderly, T., Heyman, I., Jackson, G. M., Jackson, S., Murphy, T., Rickards, H., Robertson, M., & Stern, J. (2016). Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis. Health Technology Assessment, 20(4), 1-450. https://doi.org/10.3310/hta20040

Background: Tourette syndrome (TS) is a neurodevelopmental condition characterised by chronic motor and vocal tics affecting up to 1% of school-age children and young people and is associated with significant distress and psychosocial impairment. Ob... Read More about Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis.

The clinical utility of the continuous performance test and objective measures of activity for diagnosing and monitoring ADHD in children: a systematic review (2015)
Journal Article
Hall, C. L., Valentine, A., Groom, M. J., Walker, G. M., Sayal, K., Daley, D., & Hollis, C. (2016). The clinical utility of the continuous performance test and objective measures of activity for diagnosing and monitoring ADHD in children: a systematic review. European Child and Adolescent Psychiatry, 25(7), 677-699. https://doi.org/10.1007/s00787-015-0798-x

Attention deficit hyperactivity disorder (ADHD) is typically diagnosed using clinical observation and subjective informant reports. Once children commence ADHD medication, robust monitoring is required to detect partial or non-responses. The extent t... Read More about The clinical utility of the continuous performance test and objective measures of activity for diagnosing and monitoring ADHD in children: a systematic review.

Computer games for user engagement in attention deficit hyperactivity disorder (ADHD) monitoring and therapy (2015)
Presentation / Conference Contribution
Craven, M. P., & Groom, M. J. (2015). Computer games for user engagement in attention deficit hyperactivity disorder (ADHD) monitoring and therapy.

State-of-the-art computer games and psychological tests for symptom monitoring and therapy in Attention Deficit Hyperactivity Disorder (ADHD) are explored and reviewed. Three foci for research studies are identified: task (human performance) focus; e... Read More about Computer games for user engagement in attention deficit hyperactivity disorder (ADHD) monitoring and therapy.

Morphological abnormalities in prefrontal surface area and thalamic volume in attention deficit/hyperactivity disorder (2015)
Journal Article

Although previous morphological studies have demonstrated abnormalities in prefrontal cortical thickness in children with attention deficit/hyperactivity disorder (ADHD), studies investigating cortical surface area are lacking. As the development of... Read More about Morphological abnormalities in prefrontal surface area and thalamic volume in attention deficit/hyperactivity disorder.

Differential modulation of the N2 and P3 event-related potentials by response conflict and inhibition (2015)
Journal Article
Groom, M. J., & Cragg, L. (2015). Differential modulation of the N2 and P3 event-related potentials by response conflict and inhibition. Brain and Cognition, 97, https://doi.org/10.1016/j.bandc.2015.04.004

Background: Developing reliable and specific neural markers of cognitive processes is essential to improve understanding of healthy and atypical brain function. Despite extensive research there remains uncertainty as to whether two electrophysiologic... Read More about Differential modulation of the N2 and P3 event-related potentials by response conflict and inhibition.

Snappy App: a mobile continuous performance test with physical activity measurement for assessing Attention Deficit Hyperactivity Disorder (2014)
Presentation / Conference Contribution
Young, Z., Craven, M. P., Groom, M. J., & Crowe, J. A. (2014). Snappy App: a mobile continuous performance test with physical activity measurement for assessing Attention Deficit Hyperactivity Disorder. In M. Kurosu (Ed.), Human-computer interaction: applications and services: 16th international conference, HCI International 2014, Heraklion, Crete, Greece, June 22-27, 2014, proceedings. Part III (363–373). https://doi.org/10.1007/978-3-319-07227-2_35

A Continuous Performance Test (CPT) was incorporated into a smartphone application (App) to measure three symptom domains associated with Attention Deficit Hyperactivity Disorder (ADHD); attention, impulsivity and hyperactivity. The App was pilot tes... Read More about Snappy App: a mobile continuous performance test with physical activity measurement for assessing Attention Deficit Hyperactivity Disorder.

Impulsivity and drinking motives predict problem behaviours relating to alcohol use in University students (2013)
Journal Article
Jones, K. A., Chryssanthakis, A., & Groom, M. J. (2014). Impulsivity and drinking motives predict problem behaviours relating to alcohol use in University students. Addictive Behaviors, 39(1), https://doi.org/10.1016/j.addbeh.2013.10.024

Aims: This study used a four-factor model of impulsivity to investigate inter-relationships between alcohol consumption, impulsivity, motives for drinking and the tendency to engage in alcohol-related problem behaviours. Methods: 400 University stu... Read More about Impulsivity and drinking motives predict problem behaviours relating to alcohol use in University students.

Motivational incentives and methylphenidate enhance electrophysiological correlates of error monitoring in children with attention deficit/hyperactivity disorder (2013)
Journal Article
Groom, M. J., Liddle, E. B., Scerif, G., Liddle, P. F., Batty, M. J., Liotti, M., & Hollis, C. (2013). Motivational incentives and methylphenidate enhance electrophysiological correlates of error monitoring in children with attention deficit/hyperactivity disorder. Journal of Child Psychology and Psychiatry, 54(8), https://doi.org/10.1111/jcpp.12069

Background Children with attention deficit hyperactivity disorder (ADHD) are characterised by developmentally inappropriate levels of hyperactivity, impulsivity and/or inattention and are particularly impaired when performing tasks that require a hi... Read More about Motivational incentives and methylphenidate enhance electrophysiological correlates of error monitoring in children with attention deficit/hyperactivity disorder.

Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate (2011)
Journal Article
Liddle, E. B., Hollis, C., Batty, M. J., Groom, M. J., Totman, J. J., Liotti, M., …Liddle, P. F. (2011). Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate. Journal of Child Psychology and Psychiatry, 52(7), https://doi.org/10.1111/j.1469-7610.2010.02333.x

Background: Deficits characteristic of Attention Deficit/Hyperactivity Disorder (ADHD), including poor attention and inhibitory control, are at least partially alleviated by factors that increase engagement of attention, suggesting a hypodopaminergic... Read More about Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate.

Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism (2002)
Journal Article
Bellato, A., Arora, I., Kochhar, P., Hollis, C., & Groom, M. J. (2002). Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism. Journal of Attention Disorders, 26(3), 434-446. https://doi.org/10.1177/1087054720972793

Objective. We investigated autonomic arousal, attention and response conflict, in ADHD and autism. Method. Heart rate variability (HRV), and behavioural and electrophysiological indices of performance, were recorded during a task with low and hig... Read More about Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism.