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Outputs (128)

Health net-outcome objectives and approaches for spatial planning and development: a scoping review protocol (2024)
Journal Article

Objective: The objective of this scoping review is to review the body of knowledge on net gain and no net loss (net-outcome) objectives and approaches applicable to health in spatial planning and development policies and practice. Introduction: There... Read More about Health net-outcome objectives and approaches for spatial planning and development: a scoping review protocol.

Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review (2024)
Journal Article

Background People who have had a stroke or a Transient Ischaemic Attack (TIA) can experience psychological and/or cognitive difficulties. The body of research for psychological and neuropsychological interventions after stroke is growing, however, pu... Read More about Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review.

What are the strengths and limitations to utilising creative methods in public and patient involvement in health and social care research? A qualitative systematic review (2024)
Journal Article

Background: There is increasing interest in using patient and public involvement (PPI) in research to improve the quality of healthcare. Ordinarily, traditional methods have been used such as interviews or focus groups. However, these methods tend to... Read More about What are the strengths and limitations to utilising creative methods in public and patient involvement in health and social care research? A qualitative systematic review.

Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study (2024)
Journal Article

Background: Bisphosphonates are a class of medication commonly used to treat osteoporosis. Alendronate is recommended as the first-line treatment; however, long-term adherence (both treatment compliance and persistence) is poor. Alternative bisphosph... Read More about Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study.

Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention (2024)
Journal Article

Many pregnant smokers need support to quit successfully. In the United Kingdom, trained smoking cessation advisors deliver structured behavioural counselling alongside access to free nicotine replacement therapy (NRT); known as the ‘Standard Treatmen... Read More about Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention.

The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action (2024)
Journal Article

Introduction Digital cessation support appeals to pregnant smokers. In two pooled RCTs, MiQuit, a pregnancy-specific tailored text messaging intervention, did not show effectiveness for validated prolonged abstinence. However, secondary outcomes and... Read More about The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action.

Age and sex differences in LDL cholesterol distribution in adults in Malaysia: A cross-sectional study (2010 -2021) (2023)
Journal Article

Cardiovascular disease (CVD) is the leading cause of death worldwide. Hypercholesterolaemia, especially higher low-density lipoprotein cholesterol (LDL-c), has been recognised as one of the major key risk factors for CVD. Lipid lowering treatments, s... Read More about Age and sex differences in LDL cholesterol distribution in adults in Malaysia: A cross-sectional study (2010 -2021).

Cost of the COVID-19 pandemic versus the cost-effectiveness of mitigation strategies in EU/UK/OECD: a systematic review (2023)
Journal Article

OBJECTIVES: The economic burden of COVID-19 pandemic is substantial, with both direct and indirect costs playing a significant role. DESIGN: A systematic literature review was conducted to estimate the cost of the COVID-19 pandemic and the cost-effec... Read More about Cost of the COVID-19 pandemic versus the cost-effectiveness of mitigation strategies in EU/UK/OECD: a systematic review.

Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis (2023)
Journal Article

Background Cascade testing the relatives of people with familial hypercholesterolaemia is an efficient approach to identifying familial hypercholesterolaemia. The cascade-testing protocol starts with identifying an index patient with familial hyperc... Read More about Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis.

Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study (2023)
Journal Article

Background Bisphosphonate medications, including alendronate, ibandronate and risedronate administered orally and zoledronate, administered intravenously, are commonly prescribed for the treatment of osteoporosis based on evidence that, correctly tak... Read More about Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study.

Social determinants of health and vaccine uptake during the first wave of the COVID-19 pandemic: A systematic review (2023)
Journal Article

Social determinants of health significantly impact population health status. The aim of this systematic review was to examine which social vulnerability factors or determinants of health at the individual or county level affected vaccine uptake withi... Read More about Social determinants of health and vaccine uptake during the first wave of the COVID-19 pandemic: A systematic review.

Reducing Premature Coronary Artery Disease in Malaysia by Early Identification of Familial Hypercholesterolemia Using the Familial Hypercholesterolemia Case Ascertainment Tool (FAMCAT): Protocol for a Mixed Methods Evaluation Study (2023)
Journal Article

Background: Familial hypercholesterolemia (FH) is predominantly caused by mutations in the 4 FH candidate genes (FHCGs), namely, low-density lipoprotein receptor (LDLR), apolipoprotein B-100 (APOB-100), proprotein convertase subtilisin/kexin type 9 (... Read More about Reducing Premature Coronary Artery Disease in Malaysia by Early Identification of Familial Hypercholesterolemia Using the Familial Hypercholesterolemia Case Ascertainment Tool (FAMCAT): Protocol for a Mixed Methods Evaluation Study.

Timing of Allergenic Food Introduction and Risk of Immunoglobulin E–Mediated Food Allergy: A Systematic Review and Meta-analysis (2023)
Journal Article

Importance: Earlier egg and peanut introduction probably reduce risk of egg or peanut allergy, but it is uncertain whether food allergy as a whole can be prevented using earlier allergenic food introduction. Objective: This study is a systematic r... Read More about Timing of Allergenic Food Introduction and Risk of Immunoglobulin E–Mediated Food Allergy: A Systematic Review and Meta-analysis.

The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials (2023)
Journal Article

JBI recently began the process of updating and revising its suite of critical appraisal tools to ensure that these tools remain compatible with recent developments within risk of bias science. Following a rigorous development process led by the JBI E... Read More about The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials.

Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners (2023)
Journal Article

Background: Type 2 diabetes mellitus (T2DM), a common chronic health condition, has major health and socioeconomic consequences. In the Indian subcontinent, it is a health condition for which individuals commonly consult Ayurvedic (traditional medica... Read More about Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners.

Content and quality of clinical practice guidelines for the management of type 2 diabetes in India: A systematic review (2023)
Journal Article

Introduction: Over the last few decades, India has witnessed an increase in the number of people with type 2 diabetes mellitus (T2DM). Consequently, several clinical practice guidelines (CPGs) have been developed to assist western and traditional Ind... Read More about Content and quality of clinical practice guidelines for the management of type 2 diabetes in India: A systematic review.

Systematic review of outbreaks of COVID-19 within households in the European region when the child is the index case (2023)
Journal Article

Objectives This systematic review aims to identify the secondary attack rates (SAR) to adults and other children when children are the index cases within household settings. Methods This literature review assessed European-based studies published... Read More about Systematic review of outbreaks of COVID-19 within households in the European region when the child is the index case.

Barriers and facilitators of physical activity among school attending adolescents in Lagos State, Nigeria: A qualitative study exploring views and experiences of decision-makers in secondary schools (2022)
Journal Article

Background and Aims: Schools represent a unique setting for promoting lifelong physical activity during critical development stages of life. Opportunities for in-school physical activity largely depend upon school-level policies, practices, and admin... Read More about Barriers and facilitators of physical activity among school attending adolescents in Lagos State, Nigeria: A qualitative study exploring views and experiences of decision-makers in secondary schools.

Assessing the risk of bias of quantitative analytical studies: introducing the vision for critical appraisal within JBI systematic reviews (2022)
Journal Article

A key step in the systematic review process is the assessment of the methodological quality (or risk of bias) of the included studies. At JBI, we have developed several tools to assist with this evaluation. As evidence synthesis methods continue to e... Read More about Assessing the risk of bias of quantitative analytical studies: introducing the vision for critical appraisal within JBI systematic reviews.

A clinical guideline-based management of type 2 diabetes by ayurvedic practitioners in Nepal: A feasibility cluster randomized controlled trial protocol (2022)
Journal Article

Introduction: Type 2 diabetes mellitus (T2DM) is a common chronic condition with significant health and socioeconomic consequences. In Nepal, T2DM is a common disease for which people consult ayurvedic (traditional medical system) practitioners and... Read More about A clinical guideline-based management of type 2 diabetes by ayurvedic practitioners in Nepal: A feasibility cluster randomized controlled trial protocol.

Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe (2022)
Journal Article

Background As mortality from coronavirus disease 2019 (COVID-19) is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age-/gender-adjusted data from European cohort studies... Read More about Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe.

Association of built environment constructs and physical activity among children and adolescents in Africa: a systematic review and meta-analysis (2022)
Journal Article

Objective: The objective of this review was to synthesize the association between built environment constructs and physical activity among children and adolescents in Africa. Introduction: Previous reviews have found that several built environ... Read More about Association of built environment constructs and physical activity among children and adolescents in Africa: a systematic review and meta-analysis.

Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis (2022)
Journal Article

Introduction: Many Ayurvedic medicines have the potential for managing type 2 diabetes mellitus (T2DM), with previous systematic reviews demonstrating effectiveness and safety for specific Ayurvedic medicines. However, many of the reviews need updati... Read More about Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis.

Impact of Smoking and Vaping in Films on Smoking and Vaping Uptake in Adolescents: Systematic Review and Meta-Analysis (2022)
Journal Article

Prevention of smoking uptake in young people is an essential public health target. We have previously reported a systematic review and meta-analysis of the effect of exposure to smoking imagery in films on the risk of smoking uptake in young people.... Read More about Impact of Smoking and Vaping in Films on Smoking and Vaping Uptake in Adolescents: Systematic Review and Meta-Analysis.

Assessing the effectiveness of bisphosphonates for the prevention of fragility fractures: an updated systematic review and network meta‐analyses (2022)
Journal Article

Bisphosphonates have been found to be effective in preventing fragility fractures. However, their comparative effectiveness in populations at risk has yet to be defined. In light of recent clinical trials, we aimed to compare four bisphosphonates (al... Read More about Assessing the effectiveness of bisphosphonates for the prevention of fragility fractures: an updated systematic review and network meta‐analyses.

Comparing medication adherence in patients receiving bisphosphonates for preventing fragility fractures: a comprehensive systematic review and network meta-analysis (2022)
Journal Article

Background: Bisphosphonates are effective in preventing fragility fractures; however, high rates of adherence are needed to preserve clinical benefits. Objective: To investigate persistence and compliance to oral and intravenous bisphosphonates (alen... Read More about Comparing medication adherence in patients receiving bisphosphonates for preventing fragility fractures: a comprehensive systematic review and network meta-analysis.

Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus (2021)
Journal Article

Purpose: Type 2 diabetes mellitus (T2DM) is poorly managed in the Caribbean; therefore, con-ducting an assessment of the content and quality of clinical guidelines will allow guideline de-velopers to detect and address the lacking information. Hence,... Read More about Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus.

Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care (2021)
Journal Article

Objective Familial hypercholesterolaemia (FH) is a common inherited disorder causing premature coronary heart disease (CHD) and death. We have developed the novel Familial Hypercholesterolaemia Case Ascertainment Tool (FAMCAT 1) case-finding algorith... Read More about Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care.

Effectiveness of offering tailored text message, self‐help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial (RCT) and meta‐analysis (2021)
Journal Article

Aims: To test efficacy of “MiQuit’, a tailored, self-help, text message stop smoking programme for pregnancy, as an adjunct to usual care (UC) for smoking cessation in pregnancy. Design: Multicentre, open, two-arm, parallel-group, superiority rand... Read More about Effectiveness of offering tailored text message, self‐help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial (RCT) and meta‐analysis.

Strategies for screening for familial hypercholesterolaemia in primary care and other community settings (2021)
Journal Article

Background: Familial hypercholesterolaemia is a common inherited condition that is associated with premature cardiovascular disease. The increased cardiovascular morbidity and mortality, resulting from high levels of cholesterol since birth, can be p... Read More about Strategies for screening for familial hypercholesterolaemia in primary care and other community settings.

Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis (2021)
Journal Article

Background and aims: Cascade testing in relatives of index cases is the most cost-effective approach to identifying people with familial hypercholesterolemia (FH); however, it is currently unclear which strategy to contact relatives would be the most... Read More about Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis.

Proportion of School Attending Adolescents Meeting the Recommended Moderate-to-Vigorous Physical Activity Level and Its Predictors in Lagos, Nigeria (2021)
Journal Article

We aimed to assess the proportion of school attending adolescents who reached the recommended moderate-to-vigorous physical activity (MVPA) level in Lagos State, Nigeria as well as the predictors associated with it. A cross-sectional study was conduc... Read More about Proportion of School Attending Adolescents Meeting the Recommended Moderate-to-Vigorous Physical Activity Level and Its Predictors in Lagos, Nigeria.

Understanding willingness to access and experiences of NHS Stop Smoking Services: a qualitative systematic review with meta-aggregation synthesis (2021)
Journal Article

Objectives NHS Stop Smoking Services (NHS-SSS) have been available in the United Kingdom (UK) since 2000. The service has proven to be effective, however uptake remains below aspirations. Understanding people's willingness and reasons for accessin... Read More about Understanding willingness to access and experiences of NHS Stop Smoking Services: a qualitative systematic review with meta-aggregation synthesis.

Cost-effectiveness of emergency preparedness measures in response to infectious respiratory disease outbreaks: a systematic review and econometric analysis (2021)
Journal Article

Objectives Respiratory infectious disease outbreaks pose a threat for loss of life, economic instability and social disruption. We conducted a systematic review of published econometric analyses to assess the direct and indirect costs of infectious r... Read More about Cost-effectiveness of emergency preparedness measures in response to infectious respiratory disease outbreaks: a systematic review and econometric analysis.

Barriers and facilitators to type 2 diabetes management in the Caribbean region: a qualitative systematic review (2020)
Journal Article

Objective:The objective of this systematic review was to summarize the barriers and facilitators to type 2 diabetes mellitus management in the Caribbean region.Introduction:The prevalence of type 2 diabetes mellitus in the Caribbean is of significant... Read More about Barriers and facilitators to type 2 diabetes management in the Caribbean region: a qualitative systematic review.

Using Trial Sequential Analysis for estimating the sample sizes of further trials: example using smoking cessation intervention (2020)
Journal Article

Background: Assessing benefits and harms of health interventions is resource-intensive and often requires feasibility and pilot trials followed by adequately powered randomised clinical trials. Data from feasibility and pilot trials are used to infor... Read More about Using Trial Sequential Analysis for estimating the sample sizes of further trials: example using smoking cessation intervention.

Quality of smoking cessation advice in guidelines of tobacco-related diseases: An updated systematic review (2020)
Journal Article

Tobacco smoking is a major risk factor for a wide range of diseases, and smoking cessation significantly reduces these risks. Clinical guidelines for diseases associated with smoking should therefore include guidance on smoking cessation. This review... Read More about Quality of smoking cessation advice in guidelines of tobacco-related diseases: An updated systematic review.

Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis. (2020)
Journal Article

OBJECTIVE: To explore the acceptability of different bisphosphonate regimens for the treatment of osteoporosis among patients, clinicians and managers, payers and academics. DESIGN: A systematic review of primary qualitative studies. Seven databas... Read More about Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis..

Experiences and views of women, children, and professionals regarding second-hand smoke exposure prevention in Middle Eastern countries: a qualitative systematic review protocol (2020)
Journal Article

Objective: This systematic review aims to identify and explore the experiences and views regarding secondhand smoke (SHS) exposure among women and children in the home, workplace, school, personal vehicles, and public places from the perspectives of... Read More about Experiences and views of women, children, and professionals regarding second-hand smoke exposure prevention in Middle Eastern countries: a qualitative systematic review protocol.

Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models (2020)
Journal Article

Introduction: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. With advances in early diagnosis and treatment of CVD and increasing life expectancy, more people are surviving initial CVD events. However, models t... Read More about Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models.

Effectiveness and safety of Ayurvedic medicines in type-2 diabetes management: a systematic review protocol (2020)
Journal Article

Objective: To evaluate and synthesize evidence on the effectiveness and safety of Ayurvedic medicines for managing type-2 diabetes (T2DM). Introduction: Several randomized controlled trials (RCTs) have been conducted to assess the effectiveness an... Read More about Effectiveness and safety of Ayurvedic medicines in type-2 diabetes management: a systematic review protocol.

Association of the built environment with physical activity in children and adolescents in Africa: a systematic review protocol (2019)
Journal Article

Objective: The objective of this systematic review is to summarize the association of the built environment with physical activity in children and adolescents in Africa. Introduction: Physical activity offers immense benefits to children and adolesc... Read More about Association of the built environment with physical activity in children and adolescents in Africa: a systematic review protocol.

Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis (2019)
Journal Article

Objective: Corticosteroids may be beneficial in sepsis but uncertainty remains over their effects in severe influenza. This systematic review updates the current evidence regarding corticosteroids in the treatment of influenza and examines the effect... Read More about Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis.

Incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia: a systematic review protocol (2019)
Journal Article

Objective: The objective of the systematic review is to summarize the incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia. Introduction: Several studies have been conducted in South Asia on the incid... Read More about Incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia: a systematic review protocol.

Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study (2019)
Journal Article

Background and aims: Familial hypercholesterolaemia (FH) is a known major cause of premature heart disease. However, the risks of atherosclerotic disease in other vascular regions are less known. We determined the risk of major cardiovascular disease... Read More about Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study.

Effectiveness and cost-effectiveness of a tailored text message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial and meta-analysis (2019)
Journal Article

Background: Smoking in pregnancy is a major international public health problem. Self-help support (SHS) increases the likelihood of women stopping smoking in pregnancy and delivering this kind of support by text message could be a cost-effective way... Read More about Effectiveness and cost-effectiveness of a tailored text message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial and meta-analysis.

Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults (2018)
Journal Article

© 2018 The Cochrane Collaboration. Background: Early accurate detection of all skin cancer types is important to guide appropriate management, to reduce morbidity and to improve survival. Basal cell carcinoma (BCC) is almost always a localised skin c... Read More about Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults.

The Effects of Tobacco Smoking, and Prenatal Tobacco Smoke Exposure, on Risk of Schizophrenia: A Systematic Review and Meta-Analysis (2018)
Journal Article

Introduction: The association between cigarette smoking and schizophrenia is well established. However, up to 90% of people with schizophrenia begin smoking before the onset of their illness, thus smoking could be an independent risk factor for schiz... Read More about The Effects of Tobacco Smoking, and Prenatal Tobacco Smoke Exposure, on Risk of Schizophrenia: A Systematic Review and Meta-Analysis.

Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health (2018)
Journal Article

Background: Long-term, low-level exposure to toxic elements in soil may be harmful to human health but large longitudinal cohort studies with sufficient follow-up time to study these effects are cost-prohibitive and impractical. Linkage of routinely... Read More about Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health.

Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study (2018)
Journal Article

Background and Aims: Familial hypercholesterolaemia (FH) is a major cause of premature heart disease but remains unrecognised in most patients. This study investigated if a systematic primary care-based approach to identify and manage possible FH imp... Read More about Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study.

Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study (2018)
Journal Article

Background: Smoking in pregnancy is a major public health concern. Pregnant smokers are particularly difficult to reach, with low uptake of support options and few effective interventions. Text message–based self-help is a promising, low-cost interve... Read More about Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study.

Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol) (2018)
Journal Article

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate in adult participants undergoing all types of surgery, the effects of pre-emptive and preventive non-steroidal anti-inflammatory drugs (NSAIDs) com... Read More about Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol).

Diet during pregnancy and infancy, and risk of allergic or autoimmune disease: a systematic review and meta-analysis (2018)
Journal Article

Background: There is uncertainty about the influence of diet during pregnancy and infancy on a child’s immune development. We assessed whether variations in maternal or infant diet can influence risk of allergic or autoimmune disease. Methods and fi... Read More about Diet during pregnancy and infancy, and risk of allergic or autoimmune disease: a systematic review and meta-analysis.

Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe (2017)
Journal Article

Community-acquired pneumonia (CAP) is an important respiratory disease and the fifth leading cause of mortality in Europe. The development of molecular diagnostic tests has highlighted the contributions of respiratory viruses to the aetiology of CAP,... Read More about Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe.

Large multi-centre pilot randomized controlled trial testing a low-cost, tailored, self-help smoking cessation text message intervention for pregnant smokers (MiQuit): randomized controlled trial of MiQuit (2017)
Journal Article

Aims: To estimate the effectiveness of pregnancy smoking cessation support delivered by short message service (SMS) text message and key parameters needed to plan a definitive trial. Design: Multi‐centre, parallel‐group, single‐blinded, individual r... Read More about Large multi-centre pilot randomized controlled trial testing a low-cost, tailored, self-help smoking cessation text message intervention for pregnant smokers (MiQuit): randomized controlled trial of MiQuit.

Impact of outpatient neuraminidase inhibitor treatment in patients infected with influenza A(H1N1)pdm09 at high risk of hospitalization: an Individual Participant Data (IPD) meta-analysis (2017)
Journal Article

Background: While evidence exists to support the effectiveness of neuraminidase inhibitors (NAIs) in reducing mortality when given to hospitalized patients with A(H1N1)pdm09 virus infection, the impact of outpatient treatment on hospitalization has n... Read More about Impact of outpatient neuraminidase inhibitor treatment in patients infected with influenza A(H1N1)pdm09 at high risk of hospitalization: an Individual Participant Data (IPD) meta-analysis.

A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease (2016)
Journal Article

Background Skin diseases are very common and can have a large impact on the quality of life of patients and caregivers. This programme addressed four diseases: (1) eczema, (2) vitiligo, (3) squamous cell skin cancer (SCC) and (4) pyoderma gangreno... Read More about A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease.

Timing of allergenic food to the introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis (2016)
Journal Article

Importance: Timing of introduction of allergenic foods to the infant diet may influence the risk of allergic or autoimmune disease, but the evidence for this has not been comprehensively synthesized. Objective: To systematically review and meta-a... Read More about Timing of allergenic food to the introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis.

Real-world uptake of a tailored, text message pregnancy smoking cessation programme (MiQuit) when offered online (2016)
Conference Proceeding

Background: Prenatal smoking is a major public health concern and uptake of NHS cessation support is low in this group. Text message-based self-help is a promising intervention for this population but little is known about its likely real-world uptak... Read More about Real-world uptake of a tailored, text message pregnancy smoking cessation programme (MiQuit) when offered online.

Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) (2016)
Conference Proceeding

Background: Text message cessation programmes have potential to change smoking behaviour during pregnancy but their effectiveness is unknown. This study aimed to estimate key parameters, including effectiveness and cost-effectiveness, for delivering... Read More about Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit).

Alcohol and tobacco content in UK video games and their association with alcohol and tobacco use among young people (2016)
Journal Article

Aims: To determine the extent to which video games include alcohol and tobacco content and assess the association between playing them and alcohol and smoking behaviours in adolescent players. Design: Assessment of substance in the 32 UK bestsell... Read More about Alcohol and tobacco content in UK video games and their association with alcohol and tobacco use among young people.

The association between treatment adherence to nicotine patches and smoking cessation in pregnancy (2016)
Conference Proceeding

Background: In non-pregnant “quitters,” adherence to nicotine replacement therapy (NRT) increases smoking cessation. We investigated relationships between adherence to placebo or NRT patches and cessation in pregnancy, including an assessment of reve... Read More about The association between treatment adherence to nicotine patches and smoking cessation in pregnancy.

‘Opt-out’ referrals after identifying pregnant smokers using exhaled air carbon monoxide: impact on engagement with smoking cessation support (2016)
Journal Article

Background. In the UK, free smoking cessation support is available to pregnant women; only a minority access this. ‘Opt-out’ referrals to stop smoking services (SSS) are recommended by UK guidelines. These involve identifying pregnant smokers using e... Read More about ‘Opt-out’ referrals after identifying pregnant smokers using exhaled air carbon monoxide: impact on engagement with smoking cessation support.

The association between treatment adherence to nicotine patches and smoking cessation in pregnancy: a secondary analysis of a randomised controlled trial (2016)
Journal Article

Introduction In non-pregnant ‘quitters’, adherence to nicotine replacement therapy (NRT) increases smoking cessation. We investigated relationships between adherence to placebo or NRT patches and cessation in pregnancy, including an assessment of... Read More about The association between treatment adherence to nicotine patches and smoking cessation in pregnancy: a secondary analysis of a randomised controlled trial.

Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an individual participant data meta-analysis (2016)
Journal Article

BACKGROUND: The impact of neuraminidase inhibitors (NAIs) on influenza‐related pneumonia (IRP) is not established. Our objective was to investigate the association between NAI treatment and IRP incidence and outcomes in patients hospitalised with A(H... Read More about Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an individual participant data meta-analysis.

The adaptation and uptake evaluation of an SMS text message smoking cessation programme (MiQuit) for use in antenatal care (2015)
Journal Article

Objectives: To adapt a tailored SMS text message smoking cessation intervention (MiQuit) for use without active health professional endorsement in routine antenatal care settings, to estimate ‘real world’ uptake and test the feasibility of its use. D... Read More about The adaptation and uptake evaluation of an SMS text message smoking cessation programme (MiQuit) for use in antenatal care.

Self?help educational booklets for the prevention of smoking relapse following smoking cessation treatment: a randomized controlled trial (2015)
Journal Article

Aims: Most people who quit smoking for a short term will return to smoking again in 12 months. We tested whether self-help booklets can reduce relapse in short-term quitters after receiving behavioural and pharmacological cessation treatment. Des... Read More about Self?help educational booklets for the prevention of smoking relapse following smoking cessation treatment: a randomized controlled trial.

Abstinence and relapse among smokers who use varenicline in a quit attempt-a pooled analysis of randomized controlled trials: Relapse and abstinence in smokers treated with varenicline (2015)
Journal Article

Background and aims Varenicline increases the likelihood of long-term abstinence following a quit attempt. It has been suggested that 1) part of its benefit arises from ‘recruiting into abstinence’ smokers who are not able to stop on the target quit... Read More about Abstinence and relapse among smokers who use varenicline in a quit attempt-a pooled analysis of randomized controlled trials: Relapse and abstinence in smokers treated with varenicline.

Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial (2015)
Journal Article

Background Smoking in pregnancy is a public health problem. Self-help smoking cessation support can help pregnant women to stop smoking, but the effects of delivering this kind of support via SMS text message are not known. A previous randomised... Read More about Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial.

Longitudinal cohort survey of women's smoking behaviour and attitudes in pregnancy: study methods and baseline data (2014)
Journal Article

Objectives: To report methods used to assemble a contemporary pregnancy cohort for investigating influences on smoking behaviour before, during and after pregnancy and to report characteristics of women recruited. Design: Longitudinal cohort surve... Read More about Longitudinal cohort survey of women's smoking behaviour and attitudes in pregnancy: study methods and baseline data.

Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data (2014)
Journal Article

Neuraminidase inhibitors were widely used during the 2009/10 influenza A H1N1 pandemic, but evidence for their effectiveness in reducing mortality is uncertain. We did a meta-analysis of individual participant data to investigate the association betw... Read More about Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.

Longitudinal, mixed method study to look at the experiences and knowledge of non melanoma skin cancer from diagnosis to one year (2013)
Journal Article

Background Skin cancer is the most common type of cancer in humans and the incidence is increasing worldwide. Our objective was to understanding the needs, experiences and knowledge of individuals with Non Melanoma Skin Cancer (NMSC) from diagnosis... Read More about Longitudinal, mixed method study to look at the experiences and knowledge of non melanoma skin cancer from diagnosis to one year.

Factors Associated With Smoking Cessation in Early and Late Pregnancy in the Smoking, Nicotine, and Pregnancy Trial: A Trial of Nicotine Replacement Therapy (2013)
Journal Article

Introduction: Previous studies have found partners’ smoking status, multiparity, and nicotine dependence to be associated with smoking cessation in pregnancy. However, no studies have investigated influences on cessation among women using nicotine re... Read More about Factors Associated With Smoking Cessation in Early and Late Pregnancy in the Smoking, Nicotine, and Pregnancy Trial: A Trial of Nicotine Replacement Therapy.

Second hand smoke exposure and the risk of invasive meningococcal disease in children: systematic review and meta-analysis (2012)
Journal Article

Background Invasive meningococcal disease remains an important cause of serious morbidity and mortality in children and young people. There is a growing body of literature to suggest that exposure to passive smoke may play a role in the developmen... Read More about Second hand smoke exposure and the risk of invasive meningococcal disease in children: systematic review and meta-analysis.