Professor SUSAN FRANCIS's Outputs (9)

Intradialytic Cardiac Magnetic Resonance Imaging to Assess Cardiovascular Responses in a Short-Term Trial of Hemodiafiltration and Hemodialysis (2016)
Journal Article
Buchanan, C., Mohammed, A., Cox, E., Köhler, K., Canaud, B., Taal, M. W., …McIntyre, C. W. (2017). Intradialytic Cardiac Magnetic Resonance Imaging to Assess Cardiovascular Responses in a Short-Term Trial of Hemodiafiltration and Hemodialysis. Journal of the American Society of Nephrology, 28(4), 1269-1277. https://doi.org/10.1681/ASN.2016060686

Hemodynamic stress during hemodialysis (HD) results in recurrent segmental ischemic injury (myocardial stunning) that drives cumulative cardiac damage. We performed a fully comprehensive study of the cardiovascular effect of dialysis sessions using i... Read More about Intradialytic Cardiac Magnetic Resonance Imaging to Assess Cardiovascular Responses in a Short-Term Trial of Hemodiafiltration and Hemodialysis.

Imaging the kidney using magnetic resonance techniques: structure to function (2016)
Journal Article
Mahmoud, H., Buchanan, C., Francis, S. T., & Selby, N. M. (2016). Imaging the kidney using magnetic resonance techniques: structure to function. Current Opinion in Nephrology and Hypertension, 25(6), https://doi.org/10.1097/MNH.0000000000000266

Purpose of review
Magnetic resonance imaging (MRI) offers the possibility to non-invasively assess both the structure and function of the kidney in a single MR scan session. This review summarises recent advancements in functional renal MRI techniqu... Read More about Imaging the kidney using magnetic resonance techniques: structure to function.

Field strength dependence of grey matter R2* on venous oxygenation (2016)
Journal Article
Croal, P. L., Driver, I. D., Francis, S. T., & Gowland, P. A. (2017). Field strength dependence of grey matter R2* on venous oxygenation. NeuroImage, 146, 327-332. https://doi.org/10.1016/j.neuroimage.2016.10.004

The relationship between venous blood oxygenation and change in transverse relaxation rate (ΔR2 *) plays a key role in calibrated BOLD fMRI. This relationship, defined by the parameter β, has previously been determined using theoretical simulations a... Read More about Field strength dependence of grey matter R2* on venous oxygenation.

Prior consumption of a fat meal in healthy adults modulates the brain’s response to fat (2016)
Journal Article
Eldeghaidy, S., Marciani, L., Hort, J., Hollowood, T. A., Singh, G., Bush, D., Foster, T., Taylor, A. J., Busch, J., Spiller, R. C., Gowland, P. A., & Francis, S. T. (2016). Prior consumption of a fat meal in healthy adults modulates the brain’s response to fat. Journal of Nutrition, 146(11), 2187-2198. https://doi.org/10.3945/jn.116.234104

Background: Consumption of fat is regulated by reward and homeostatic pathways, but no studies have examined the role of the intake of a high fat meal (HFM) on subsequent brain activation to oral stimuli.
Objective: We evaluated how prior consumptio... Read More about Prior consumption of a fat meal in healthy adults modulates the brain’s response to fat.

Non-invasive assessment of portal hypertension using quantitative magnetic resonance imaging (2016)
Journal Article
Palaniyappan, N., Cox, E., Bradley, C., Scott, R., Austin, A., O’Neill, R., Ramjas, G., Travis, S., White, H., Singh, R., Thurley, P., Guha, I. N., Francis, S., & Aithal, G. P. (2016). Non-invasive assessment of portal hypertension using quantitative magnetic resonance imaging. Journal of Hepatology, 65(6), 1131-1139. https://doi.org/10.1016/j.jhep.2016.07.021

Background & Aims

Hepatic venous pressure gradient (HVPG) measurement is currently the only validated technique to accurately evaluate changes in portal pressure. In this study, we evaluate the use of non-contrast quantitative magnetic resonance i... Read More about Non-invasive assessment of portal hypertension using quantitative magnetic resonance imaging.

Mapping quantal touch using 7 Tesla functional magnetic resonance imaging and single-unit intraneural microstimulation (2016)
Journal Article
Sanchez Panchuelo, R., Ackerley, R. M., Glover, P. M., Bowtell, R. W., Wessberg, J., Francis, S. T., & McGlone, F. (2016). Mapping quantal touch using 7 Tesla functional magnetic resonance imaging and single-unit intraneural microstimulation. eLife, 5(MAY2016), Article e.Life.12812. https://doi.org/10.7554/elife.12812

Using ultra-high field 7 Tesla (7T) functional magnetic resonance imaging (fMRI), we map the cortical and perceptual responses elicited by intraneural microstimulation (INMS) of single mechanoreceptive afferent units in the median nerve, in humans. A... Read More about Mapping quantal touch using 7 Tesla functional magnetic resonance imaging and single-unit intraneural microstimulation.

Anticipation of thermal pain in diverticular disease (2016)
Journal Article
Smith, J. K., Marciani, L., Humes, D. J., Francis, S. T., Gowland, P. A., & Spiller, R. C. (2016). Anticipation of thermal pain in diverticular disease. Neurogastroenterology and Motility, 28(6), https://doi.org/10.1111/nmo.12790

Background
The relative importance of peripheral nerve injury or differences in central pain processing in painful diverticular disease (DD) is unclear. Functional MRI has demonstrated changes in the anticipation of pain in irritable bowel syndrom... Read More about Anticipation of thermal pain in diverticular disease.

Thermal taster status: evidence of cross-modal integration (2016)
Journal Article
Hort, J., Ford, R. A., Eldeghaidy, S., & Francis, S. T. (2016). Thermal taster status: evidence of cross-modal integration. Human Brain Mapping, 37(6), 2263-2275. https://doi.org/10.1002/hbm.23171

Thermal taster status refers to the finding that, in some individuals, thermal stimulation of the tongue elicits a phantom taste. Little is known regarding the mechanism for this, it is hypothesised to be a result of cross-wiring between gustatory an... Read More about Thermal taster status: evidence of cross-modal integration.

Global signal modulation of single-trial fMRI response variability: effect on positive vs negative BOLD response relationship (2016)
Journal Article
Mayhew, S. D., Mullinger, K. J., Ostwald, D., Porcaro, C., Bowtell, R. W., Bagshaw, A. P., & Francis, S. T. (2016). Global signal modulation of single-trial fMRI response variability: effect on positive vs negative BOLD response relationship. NeuroImage, 133, https://doi.org/10.1016/j.neuroimage.2016.02.077

In functional magnetic resonance imaging (fMRI), the relationship between positive BOLD responses (PBRs) and negative BOLD responses (NBRs) to stimulation is potentially informative about the balance of excitatory and inhibitory brain responses in se... Read More about Global signal modulation of single-trial fMRI response variability: effect on positive vs negative BOLD response relationship.