Mutation and selection explain why many eukaryotic centromeric DNA sequences are often A+T rich

Barbosa, Anne C; Xu, Zhengyao; Karari, Kazhal; Williams, Wendi; Hauf, Silke; Brown, William R A

doi:10.1093/nar/gkab1219

All Outputs (1)

Mutation and selection explain why many eukaryotic centromeric DNA sequences are often A+T rich (2021)
Journal Article
Barbosa, A. C., Xu, Z., Karari, K., Williams, W., Hauf, S., & Brown, W. R. A. (2022). Mutation and selection explain why many eukaryotic centromeric DNA sequences are often A+T rich. Nucleic Acids Research, 50(1), 579-596. https://doi.org/10.1093/nar/gkab1219

We have used chromosome engineering to replace native centromeric DNA with different test sequences at native centromeres in two different strains of the fission yeast Schizosaccharomyces pombe and have discovered that A + T rich DNA, whether synthet... Read More about Mutation and selection explain why many eukaryotic centromeric DNA sequences are often A+T rich.