All Outputs (4)

Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling (2020)
Journal Article
Kotowska, A. M., Trindade, G. F., Mendes, P. M., Williams, P. M., Aylott, J. W., Shard, A. G., …Scurr, D. J. (2020). Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling. Nature Communications, 11(1), Article 5832. https://doi.org/10.1038/s41467-020-19445-x

Label-free protein characterization at surfaces is commonly achieved using digestion and/or matrix application prior to mass spectrometry. We report the assignment of undigested proteins at surfaces in situ using secondary ion mass spectrometry (SIMS... Read More about Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling.

Advancements in the co-formulation of biologic therapeutics (2020)
Journal Article
Chauhan, V. M., Zhang, H., Dalby, P. A., & Aylott, J. W. (2020). Advancements in the co-formulation of biologic therapeutics. Journal of Controlled Release, 327, 397-405. https://doi.org/10.1016/j.jconrel.2020.08.013

Mass Transport of Lipopolysaccharide induced H2O2 detected by an Intracellular Carbon Nanoelectrode Sensor (2020)
Journal Article
Hicks, J., Silman, N., Jackson, S., Aylott, J., & Rawson, F. (2020). Mass Transport of Lipopolysaccharide induced H2O2 detected by an Intracellular Carbon Nanoelectrode Sensor. Bioelectrochemistry, https://doi.org/10.1016/j.bioelechem.2020.107547

Facile Dye-Initiated Polymerization of Lactide–Glycolide Generates Highly Fluorescent Poly(lactic-co-glycolic Acid) for Enhanced Characterization of Cellular Delivery (2020)
Journal Article
Al-Natour, M. A., Yousif, M. D., Cavanagh, R., Abouselo, A., Apebende, E. A., Ghaemmaghami, A., …Alexander, C. (2020). Facile Dye-Initiated Polymerization of Lactide–Glycolide Generates Highly Fluorescent Poly(lactic-co-glycolic Acid) for Enhanced Characterization of Cellular Delivery. ACS Macro Letters, 9(3), 431-437. https://doi.org/10.1021/acsmacrolett.9b01014

Copyright © 2020 American Chemical Society. Poly(lactic-co-glycolic acid) (PLGA) is a versatile synthetic copolymer that is widely used in pharmaceutical applications. This is because it is well-tolerated in the body, and copolymers of varying physic... Read More about Facile Dye-Initiated Polymerization of Lactide–Glycolide Generates Highly Fluorescent Poly(lactic-co-glycolic Acid) for Enhanced Characterization of Cellular Delivery.