SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians
(2012)
Journal Article
Gonzalez-Estevez, C., Felix, D. A., Smith, M. D., Paps, J., Morley, S. J., James, V., …Aboobaker, A. A. (2012). SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians. PLoS Genetics, 8(3), Article e1002619. https://doi.org/10.1371/journal.pgen.1002619
Planarian flatworms are able to both regenerate their whole bodies and continuously adapt their size to nutrient status. Tight control of stem cell proliferation and differentiation during these processes is the key feature of planarian biology. Here... Read More about SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians.