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All Outputs (19)

The Cochrane Skin Group: a vanguard for developing and promoting evidence-based dermatology (2013)
Journal Article
Reddi, A., Prescott, L., Doney, E., Delamere, F., Kollipara, R., Dellavalle, R. P., & Williams, H. C. (2013). The Cochrane Skin Group: a vanguard for developing and promoting evidence-based dermatology. Journal of Evidence-Based Medicine, 6(4), https://doi.org/10.1111/jebm.12068

Aim
The Cochrane Skin Group (CSG) is part of the international Cochrane Collaboration (http://www.cochrane.org/). The CSG prepares, maintains and disseminates high quality evidence-based summaries on the prevention, diagnosis and treatment of skin d... Read More about The Cochrane Skin Group: a vanguard for developing and promoting evidence-based dermatology.

Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10 (2013)
Journal Article
Franks, H. A., Wang, Q., Lax, S. J., Colllins, M. K., Escors, D., Patel, P. M., & Jackson, A. M. (2014). Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10. International Journal of Cancer, 134(3), 575-586. https://doi.org/10.1002/ijc.28398

There is growing interest in myeloid (my) dendritic cells (DC) as an alternative to monocyte-derived DC (moDC) for immunotherapy. However, in contrast to moDC, little is known regarding the effect of malignancy on the function, abundance or use of in... Read More about Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10.

Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies (2013)
Journal Article
Kulkarn, B. B. .., Powe, D. G., Hopkinson, A., & Dua, H. S. (2013). Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies. BMC Ophthalmology, 13, Article 62. https://doi.org/10.1186/1471-2415-13-62

Background
The most important challenge of performing insitu transcriptional profiling of the human ocular surface epithelial regions is obtaining samples in sufficient amounts, without contamination from adjacent tissue, as the region of interest i... Read More about Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies.

Psychosocial risk assessment in organizations: concurrent validity of the brief version of the Management Standards Indicator Tool (2013)
Journal Article
Houdmont, J., Randall, R., Kerr, R., & Addley, K. (2013). Psychosocial risk assessment in organizations: concurrent validity of the brief version of the Management Standards Indicator Tool. Work and Stress, 27(4), https://doi.org/10.1080/02678373.2013.843607

The Management Standards Indicator Tool (MSIT) is a 35-item self-report measure of the psychosocial work environment designed to assist organizations with psychosocial risk assessment. It is also used in work environment research. Edwards and Webster... Read More about Psychosocial risk assessment in organizations: concurrent validity of the brief version of the Management Standards Indicator Tool.

Report of the first veterinary student support workshop (2013)
Journal Article
Kydd, J. H., Cobb, K., Davis, R., Dean, R., Drinkwater, J., Dunham, S., Flynn, R., Gray, C., Grogono-Thomas, R., Hagan, P., Jefferies, A., Jones, M., Ogden, C., Pearson, G., Robinson, N., Rutland, C., Tarlinton, R., Tötemeyer, S., Wason, J., Whittington, R., …Mossop, L. (2013). Report of the first veterinary student support workshop. Veterinary Record, 173(14), 346. https://doi.org/10.1136/vr.101782

Tobacco smoking, associated risk behaviours, and experience with quitting: a qualitative study with homeless smokers addicted to drugs and alcohol (2013)
Journal Article
Garner, L., & Ratschen, E. (2013). Tobacco smoking, associated risk behaviours, and experience with quitting: a qualitative study with homeless smokers addicted to drugs and alcohol. BMC Public Health, 13, Article 951. https://doi.org/10.1186/1471-2458-13-951

Background
The prevalence of tobacco smoking among homeless people can reach more than 90%, with related morbidity and mortality being high. However, research in this area is scarce. This study aims to explore smoking and quitting related behaviours... Read More about Tobacco smoking, associated risk behaviours, and experience with quitting: a qualitative study with homeless smokers addicted to drugs and alcohol.

Development of a new SonovueTM contrast-enhanced ultrasound approach reveals temporal and age-related features of muscle microvascular responses to feeding (2013)
Journal Article
features of muscle microvascular responses to feeding. Physiological Reports, 1(5), Article e00119. https://doi.org/10.1002/phy2.119

Compromised limb blood flow in aging may contribute to the development of sarcopenia, frailty, and the metabolic syndrome. We developed a novel contrast-enhanced ultrasound technique using Sonovue™ to characterize muscle microvasculature responses to... Read More about Development of a new SonovueTM contrast-enhanced ultrasound approach reveals temporal and age-related features of muscle microvascular responses to feeding.

Menopause and work: an electronic survey of employees’ attitudes in the UK (2013)
Journal Article
Griffiths, A., MacLennen, S. J., & Hassard, J. (2013). Menopause and work: an electronic survey of employees’ attitudes in the UK. Maturitas, 76(2), https://doi.org/10.1016/j.maturitas.2013.07.005

Objectives: This study explored women's experiences of working through menopausal transition in the UK. It aimed to identify the perceived effects of menopausal symptoms on working life, to outline the perceived effects of work on menopausal symptoms... Read More about Menopause and work: an electronic survey of employees’ attitudes in the UK.

Evidence-based lumbar puncture: best practice to prevent headache (2013)
Journal Article
Cooper, N. (2022). Evidence-based lumbar puncture: best practice to prevent headache. British Journal of Hospital Medicine, 63(10), 598-599. https://doi.org/10.12968/hosp.2002.63.10.1930

Lumbar puncture is routinely used to access cerebrospinal fluid. Headache is the most common complication, and can be debilitating. The risk of headache is related to age, sex, needle size and shape, and lumbar puncture procedure. Doctors continue to... Read More about Evidence-based lumbar puncture: best practice to prevent headache.

Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis (2013)
Journal Article
Monaghan, T. M., Robins, A., Knox, A., Sewell, H. F., & Mahida, Y. R. (2013). Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis. PLoS ONE, 8(9), Article e74452. https://doi.org/10.1371/journal.pone.0074452

C. difficile infection (CDI) is rarely reported in cystic fibrosis (CF) patients despite frequent hospitalisations and
antibiotic usage. Conversely, the prevalence of CDI in inflammatory bowel disease (IBD) has received increased
attention. We inve... Read More about Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis.

Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI (2013)
Journal Article
Lilburn, D. M., Hughes-Riley, T., Six, J. S., Stupic, K. F., Shaw, D. E., Pavlovskaya, G. E., & Meersmann, T. (2013). Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI. PLoS ONE, 8(8), Article e73468. https://doi.org/10.1371/journal.pone.0073468

Ex vivo rodent lung models are explored for physiological measurements of respiratory function with hyperpolarized (hp) 129Xe MRI. It is shown that excised lung models allow for simplification of the technical challenges involved and provide valuable... Read More about Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI.

Neural primacy of the salience processing system in schizophrenia (2013)
Journal Article
Palaniyappan, L., Simmonite, M., White, T., Liddle, E., & Liddle, P. (2013). Neural primacy of the salience processing system in schizophrenia. Neuron, 79(4), https://doi.org/10.1016/j.neuron.2013.06.027

For effective information processing, two large-scale distributed neural networks appear to be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex (DLPFC) and a salience system anchored on the anterior insula. Aberr... Read More about Neural primacy of the salience processing system in schizophrenia.

A survey of tobacco dependence treatment guidelines in 121 countries (2013)
Journal Article
Piné-Abata, H., McNeill, A., Raw, M., Bitton, A., Rigotti, N., & Murray, R. (2013). A survey of tobacco dependence treatment guidelines in 121 countries. Addiction, 108(8), https://doi.org/10.1111/add.12158

Aims
To report progress among Parties to the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) in developing national tobacco treatment guidelines in accordance with FCTC Article 14 guideline recommendations.

Design... Read More about A survey of tobacco dependence treatment guidelines in 121 countries.

Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics (2013)
Journal Article
Tench, C. R., Tanasescu, R., Auer, D. P., & Constantinescu, C. S. (2013). Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics. PLoS ONE, 8(7), Article e70143. https://doi.org/10.1371/journal.pone.0070143

Coordinate based meta-analysis (CBMA) is widely used to find regions of consistent activation across fMRI studies that have been selected for their functional relevance to a given hypothesis. Only reported coordinates (foci), and a model of their spa... Read More about Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics.

HTR4 gene structure and altered expression in the developing lung (2013)
Journal Article
Hodge, E., Nelson, C. P., Miller, S., Billington, C. K., Stewart, C. E., Swan, C., Malarstig, A., Henry, A. P., Gowland, C., Melén, E., Hall, I. P., & Sayers, I. (2013). HTR4 gene structure and altered expression in the developing lung. Respiratory Research, 14(77), https://doi.org/10.1186/1465-9921-14-77

Background: Meta-analyses of genome-wide association studies (GWAS) have identified single nucleotide
polymorphisms (SNPs) spanning the 5-hydroxytryptamine receptor 4 (5-HT4R) gene (HTR4) associated with lung
function. The aims of this study were t... Read More about HTR4 gene structure and altered expression in the developing lung.

‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services (2013)
Journal Article
Hall, C. L., Newell, K., Taylor, J., Sayal, K., Swift, K. D., & Hollis, C. (2013). ‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services. BMC Psychiatry, 13(186), https://doi.org/10.1186/1471-244X-13-186

Background: Once considered to be a disorder restricted to childhood, Attention Deficit/Hyperactivity Disorder (ADHD) is now recognised to persist into adult life. However, service provision for adults with ADHD is limited. Additionally, there is lit... Read More about ‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services.

The UK clinical aptitude test and clinical course performance at Nottingham: a prospective cohort study (2013)
Journal Article
Yates, J., & James, D. (2013). The UK clinical aptitude test and clinical course performance at Nottingham: a prospective cohort study. BMC Medical Education, 13, Article 32. https://doi.org/10.1186/1472-6920-13-32

Background
The UK Clinical Aptitude Test (UKCAT) was introduced in 2006 as an additional tool for the selection of medical students. It tests mental ability in four distinct domains (Verbal Reasoning, Quantitative Reasoning, Abstract Reasoning, and... Read More about The UK clinical aptitude test and clinical course performance at Nottingham: a prospective cohort study.