All Outputs (1070)

Exploring the Impact of Different Approaches to Healthcare Support for Older Care Home Residents in Greater Manchester on Ambulance Services and Unplanned Hospital Admissions (2024)
Journal Article
Hargreaves, C., Tucker, S., Hughes, J., Hothersall, G., Patterson, M., Gillan, V., & Challis, D. (2024). Exploring the Impact of Different Approaches to Healthcare Support for Older Care Home Residents in Greater Manchester on Ambulance Services and Unplanned Hospital Admissions. Journal of Long-Term Care, 2024, 489-499. https://doi.org/10.31389/jltc.339

Context:

Meeting the healthcare needs of care home residents is an international concern. In England, three approaches to enhance usual care provided by primary care general practitioners have been identified: additional direct (face-to-face) sup... Read More about Exploring the Impact of Different Approaches to Healthcare Support for Older Care Home Residents in Greater Manchester on Ambulance Services and Unplanned Hospital Admissions.

Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational-level data (2024)
Journal Article
Dulal-Arthur, T., Hassard, J., Bourke, J., Wishart, M., Bartle, C., Roper, S., Belt, V., Leka, S., Pahl, N., Thomson, L., & Blake, H. (2025). Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational-level data. Journal of Occupational and Organizational Psychology, 98(1), Article e12552. https://doi.org/10.1111/joop.12552

Presenteeism (working while ill) due to mental ill-health is estimated to be one of the largest economic costs to employers. We seek to investigate the relationship between line manager training in mental health (MH) and presenteeism trends at work.... Read More about Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational-level data.

Providing emotional support during the process of multiple sclerosis diagnosis (PrEliMS): A feasibility randomised controlled trial (2024)
Journal Article
Das Nair, R., Mhizha-Murira, J. R., Topcu, G., Tindall, T., Bale, C., Moghaddam, N., Scheffler-Ansari, G., Drummond, A., Fitzsimmons, D., & Evangelou, N. (2024). Providing emotional support during the process of multiple sclerosis diagnosis (PrEliMS): A feasibility randomised controlled trial. Clinical Rehabilitation, 38(11), 1506-1520. https://doi.org/10.1177/02692155241284781

Objectives
To evaluate the feasibility and acceptability of an emotional support programme for newly diagnosed people with multiple sclerosis.

Design
Three-arm, mixed methods, randomised controlled trial comparing usual care, versus usual care p... Read More about Providing emotional support during the process of multiple sclerosis diagnosis (PrEliMS): A feasibility randomised controlled trial.

The Mechanisms of Persisting Disability in Schizophrenia: Imprecise Predictive Coding via Corticostriatothalamic-Cortical Loop Dysfunction (2024)
Journal Article
Liddle, P. F., & Sami, M. B. (2024). The Mechanisms of Persisting Disability in Schizophrenia: Imprecise Predictive Coding via Corticostriatothalamic-Cortical Loop Dysfunction. Biological Psychiatry, https://doi.org/10.1016/j.biopsych.2024.08.007

Persisting symptoms and disability remain a problem for an appreciable proportion of people with schizophrenia despite treatment with antipsychotic medication. Improving outcomes requires an understanding of the nature and mechanisms of the pathologi... Read More about The Mechanisms of Persisting Disability in Schizophrenia: Imprecise Predictive Coding via Corticostriatothalamic-Cortical Loop Dysfunction.

Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences (2024)
Preprint / Working Paper
Deakin, B., Liddle, E., Rathnaiah, M., Gregory, C., Katshu, M., Wiliams, G., Conen, S., Smallman, R., Koelewijn, L. C., Anton, A., Kumar, J., Gasgoyne, L. E., Chen, C., Nikkheslat, N., Evans, J., Lanz, B., Walters, J., Talbot, P., Palaniyappan, L., Singh, K. D., …Liddle, P. F. Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences

It is widely thought that the onset of psychotic symptoms in schizophrenia may arise from an early neurotoxic phase, possibly related to oxidative stress or inflammation, and a late residual damage phase associated with persistent negative symptoms.... Read More about Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences.

Tracking subjects' strategies in behavioural choice experiments at trial resolution. (2024)
Journal Article
Maggi, S., Hock, R. M., O'Neill, M., Buckley, M. J., Moran, P. M., Bast, T., Sami, M., & Humphries, M. D. (2024). Tracking subjects' strategies in behavioural choice experiments at trial resolution. eLife, 13, Article e86491. https://doi.org/10.7554/eLife.86491

Investigating how, when, and what subjects learn during decision-making tasks requires tracking their choice strategies on a trial-by-trial basis. Here we present a simple but effective probabilistic approach to tracking choice strategies at trial re... Read More about Tracking subjects' strategies in behavioural choice experiments at trial resolution..

Realist Evaluation Comparison of Dementia-Friendly Communities in England and the Netherlands (2024)
Journal Article
Chadborn, N. H., Thijssen, M., Logan, P., Radford, K., & Graff, M. (2024). Realist Evaluation Comparison of Dementia-Friendly Communities in England and the Netherlands. Health and Social Care in the Community, 2024, Article 5576029. https://doi.org/10.1155/2024/5576029

Introduction. Dementia-friendly communities coordinate activities and events which offer social inclusion and participation of people with dementia. Initiatives can include memory cafés, sports, and tourist and heritage visits. This study explored ho... Read More about Realist Evaluation Comparison of Dementia-Friendly Communities in England and the Netherlands.

Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for treatment-resistant depression: a randomized controlled trial (2024)
Journal Article
Morriss, R., Briley, P. M., Webster, L., Abdelghani, M., Barber, S., Bates, P., Brookes, C., Hall, B., Ingram, L., Kurkar, M., Lankappa, S., Liddle, P. F., McAllister-Williams, R. H., O’Neil-Kerr, A., Pszczolkowski, S., Suazo Di Paola, A., Walters, Y., & Auer, D. P. (2024). Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for treatment-resistant depression: a randomized controlled trial. Nature Medicine, 30(2), 403–413. https://doi.org/10.1038/s41591-023-02764-z

Disruption in reciprocal connectivity between the right anterior insula and the left dorsolateral prefrontal cortex is associated with depression and may be a target for neuromodulation. In a five-center, parallel, double-blind, randomized controlled... Read More about Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for treatment-resistant depression: a randomized controlled trial.

Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation (2023)
Journal Article
Hollis, C., Hall, C. L., Khan, K., Le Novere, M., Marston, L., Jones, R., Hunter, R., Brown, B. J., Sanderson, C., Andrén, P., Bennett, S. D., Chamberlain, L. R., Bethan Davies, E., Evans, A., Kouzoupi, N., McKenzie, C., Heyman, I., Kilgariff, J., Glazebrook, C., Mataix-Cols, D., …Murphy, T. (2023). Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation. Health Technology Assessment, 27(18), 1-120. https://doi.org/10.3310/cpms3211

Background:

Behavioural therapy for tics is difficult to access, and little is known about its effectiveness when delivered online.

Objective:

To investigate the clinical and cost-effectiveness of an online-delivered, therapist and parent-... Read More about Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation.

Relationship Between Occupational Safety and Health Policy Principles, Organizational Action on Work-related Stress and the Psychosocial Work Environment in Italy (2023)
Journal Article
Leka, S., Torres, L., Jain, A., Di Tecco, C., Russo, S., & Iavicoli, S. (in press). Relationship Between Occupational Safety and Health Policy Principles, Organizational Action on Work-related Stress and the Psychosocial Work Environment in Italy. Safety and Health at Work, https://doi.org/10.1016/j.shaw.2023.10.001

Background: It is acknowledged that legislation acts as a motivator for organizational action on psychosocial risks. Our study aims to provide evidence on the relationship between key occupational safety and health (OSH) policy principles and organiz... Read More about Relationship Between Occupational Safety and Health Policy Principles, Organizational Action on Work-related Stress and the Psychosocial Work Environment in Italy.

Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis. (2023)
Journal Article
Murray, A. J., Humpston, C. S., Wilson, M., Rogers, J. C., Zia Ul Haq Katshu, M., Liddle, P. F., & Upthegrove, R. (2024). Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis. Brain, Behavior, and Immunity, 115, 3-12. https://doi.org/10.1016/j.bbi.2023.09.017

Oxidative stress may contribute to declining course and poor outcomes in psychosis. However, in vivo Magnetic Resonance Spectroscopy studies yield disparate results due to clinical stage, sample demographics, neuroanatomical focus, sample size, and a... Read More about Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis..

Training for line managers should focus on primary prevention of mental ill-health at work (2023)
Journal Article
Blake, H., Hassard, J., Bartle, C., & Thomson, L. (2023). Training for line managers should focus on primary prevention of mental ill-health at work. Perspectives in Public Health, 143(3), 124-125. https://doi.org/10.1177/17579139231157528

The potential of responsible business to promote sustainable work – An analysis of CSR/ESG instruments (2023)
Journal Article
Torres, L., Ripa, D., Jain, A., Herrero, J., & Leka, S. (2023). The potential of responsible business to promote sustainable work – An analysis of CSR/ESG instruments. Safety Science, 164, Article 106151. https://doi.org/10.1016/j.ssci.2023.106151

In the last few years important efforts have been made to rationalise the growing corporate sustainability or CSR/ESG standards field aiming at achieving some degree of harmonisation. Yet, these efforts might be unable to capture the diversity of CSR... Read More about The potential of responsible business to promote sustainable work – An analysis of CSR/ESG instruments.

How are adverse events identified and categorised in trials of digital mental health interventions? A narrative scoping review of trials in the ISRCTN registry (2023)
Journal Article
Bergin, A. D. G., Valentine, A. Z., Rennick Egglestone, S., Slade, M., Hollis, C., & Hall, C. L. (2023). How are adverse events identified and categorised in trials of digital mental health interventions? A narrative scoping review of trials in the ISRCTN registry. JMIR Mental Health, 10, Article e42501. https://doi.org/10.2196/42501

Background: To contextualize the benefits of an intervention, it is important that adverse events (AEs) are reported. This is potentially difficult in trials of digital mental health interventions, where delivery may be remote and the mechanisms of a... Read More about How are adverse events identified and categorised in trials of digital mental health interventions? A narrative scoping review of trials in the ISRCTN registry.

Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study (2023)
Journal Article
Tindall, T., Topcu, G., Thomas, S., Bale, C., Evangelou, N., Drummond, A., & das Nair, R. (2023). Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study. Health Expectations, 26(2), 858-868. https://doi.org/10.1111/hex.13711

Background: Diagnosing multiple sclerosis (MS) can be a lengthy process, which can impact psychological wellbeing, condition management, and future engagement with health services. Therefore, providing timely and appropriate emotional support may imp... Read More about Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study.

Understanding the Impact of Home Confinement on Children and Young People with ADHD and ASD During the COVID-19 Pandemic (2023)
Journal Article
Hall, C. L., Partlett, C., Valentine, A. Z., Pearcey, S., & Sayal, K. (2023). Understanding the Impact of Home Confinement on Children and Young People with ADHD and ASD During the COVID-19 Pandemic. Child Psychiatry and Human Development, 55(5), 1279-1293. https://doi.org/10.1007/s10578-022-01490-w

To understand whether the mental health of children and young people (CYP) with and without attention-deficit/hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD) were differentially affected by COVID-19. We analysed data (n = 6507) fr... Read More about Understanding the Impact of Home Confinement on Children and Young People with ADHD and ASD During the COVID-19 Pandemic.

‘Getting to know you through music.’ Music therapists’ unique ways of ‘knowing’ their clients and our collective responsibilities to articulate our implicit knowledge (2023)
Journal Article
McDermott, O. (2023). ‘Getting to know you through music.’ Music therapists’ unique ways of ‘knowing’ their clients and our collective responsibilities to articulate our implicit knowledge. Nordic Journal of Music Therapy, 32(1), 1-3. https://doi.org/10.1080/08098131.2022.2152238

“How do you get to know your client’s inner-world so well?” I am often amazed by the depth of insight music therapy colleagues share about their clients during clinical peer-supervision. Of course, colleagues from other disciplines I closely work wit... Read More about ‘Getting to know you through music.’ Music therapists’ unique ways of ‘knowing’ their clients and our collective responsibilities to articulate our implicit knowledge.

Dementia and hearing-aid use: a two-way street (2022)
Journal Article
Naylor, G., Dillard, L., Orrell, M., Stephan, B. C. M., Zobay, O., & Saunders, G. H. (2022). Dementia and hearing-aid use: a two-way street. Age and Ageing, 51(12), Article afac266. https://doi.org/10.1093/ageing/afac266

Objectives
Hearing-aid use may reduce risk of dementia, but cognitive impairment makes use more challenging. An observed association between reduced hearing-aid use and incident dementia could reflect either or both of these causal paths. The object... Read More about Dementia and hearing-aid use: a two-way street.

Distance learning during the COVID-19 pandemic for children with ADHD and/or ASD: a European multi-center study examining the role of executive function deficits and age (2022)
Journal Article
Thorell, L. B., Fuermaier, A. B. M., Christiansen, H., Steinmayr, R., Baeyens, D., de la Peña, A. G., Groom, M. J., Idrees, I., van der Oord, S., van den Hoofdakker, B. J., Luman, M., Mammarella, I. C., & Skoglund, C. (2022). Distance learning during the COVID-19 pandemic for children with ADHD and/or ASD: a European multi-center study examining the role of executive function deficits and age. Child and Adolescent Psychiatry and Mental Health, 16(1), Article 101. https://doi.org/10.1186/s13034-022-00540-4

Background: One of the COVID-19 pandemic consequences that has affected families the most is school lockdowns. Some studies have shown that distance learning has been especially challenging for families with a child with neurodevelopmental disorders... Read More about Distance learning during the COVID-19 pandemic for children with ADHD and/or ASD: a European multi-center study examining the role of executive function deficits and age.

Online Parent Training for The Initial Management of ADHD referrals (OPTIMA): the protocol for a randomised controlled trial of a digital parenting intervention implemented to support parents and children on a treatment waitlist (2022)
Journal Article
Kostyrka-Allchorne, K., Ballard, C., Byford, S., Cortese, S., Daley, D., Downs, J., French, B., Glazebrook, C., Goldsmith, K., Hall, C. L., Hedstrom, E., Kovshoff, H., Kreppner, J., Lean, N., Sayal, K., Shearer, J., Simonoff, E., Thompson, M., & Sonuga-Barke, E. J. S. (2022). Online Parent Training for The Initial Management of ADHD referrals (OPTIMA): the protocol for a randomised controlled trial of a digital parenting intervention implemented to support parents and children on a treatment waitlist. Trials, 23(1), Article 1003. https://doi.org/10.1186/s13063-022-06952-z

Background: Children referred for attention-deficit/hyperactivity disorder (ADHD) often present with a broader pattern of conduct problems including oppositionality and defiance. This combination can be extremely stressful to parents, lower parents’... Read More about Online Parent Training for The Initial Management of ADHD referrals (OPTIMA): the protocol for a randomised controlled trial of a digital parenting intervention implemented to support parents and children on a treatment waitlist.