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All Outputs (3)

Fecal Microbiota Transplantation: Current Challenges and Future Landscapes (2024)
Journal Article
Yadegar, A., Bar-Yoseph, H., Monaghan, T. M., Severino, A., Pakpour, S., Kuijper, E. J., …Kao, D. (in press). Fecal Microbiota Transplantation: Current Challenges and Future Landscapes. Clinical Microbiology Reviews,

Given the importance of gut microbial homeostasis in maintaining health, there has been considerable interest in developing innovative therapeutic strategies for restoring gut microbiota. One such approach, fecal microbiota transplantation (FMT), is... Read More about Fecal Microbiota Transplantation: Current Challenges and Future Landscapes.

Case Series: Efficacy of Polyclonal Intravenous Immunoglobulin for Refractory Clostridioides difficile Infection (2024)
Journal Article
Ragan, S. A., Doyle, C., Datta, N., Abdic, H., Wilcox, M. H., Montgomery, R., …Monaghan, T. M. (2024). Case Series: Efficacy of Polyclonal Intravenous Immunoglobulin for Refractory Clostridioides difficile Infection. Antibodies, 13(2), Article 26. https://doi.org/10.3390/antib13020026

Background: Intravenous immunoglobulin (IVIg) for Clostridioides difficile infection (CDI) no longer features in treatment guidelines. However, IVIg is still used by some clinicians for severe or recurrent CDI (rCDI) cases. The main objective of this... Read More about Case Series: Efficacy of Polyclonal Intravenous Immunoglobulin for Refractory Clostridioides difficile Infection.

Protective effects of fecal microbiota transplantation against ischemic stroke and other neurological disorders: an update (2024)
Journal Article
Hediyal, T. A., Vichitra, C., Anand, N., Bhaskaran, M., Essa, S. M., Kumar, P., …Chidambaram, S. B. (2024). Protective effects of fecal microbiota transplantation against ischemic stroke and other neurological disorders: an update. Frontiers in Immunology, 15, Article 1324018. https://doi.org/10.3389/fimmu.2024.1324018

The bidirectional communication between the gut and brain or gut-brain axis is regulated by several gut microbes and microbial derived metabolites, such as short-chain fatty acids, trimethylamine N-oxide, and lipopolysaccharides. The Gut microbiota (... Read More about Protective effects of fecal microbiota transplantation against ischemic stroke and other neurological disorders: an update.