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All Outputs (73)

Smoking in the home after childbirth: prevalence and determinants in an English cohort (2015)
Journal Article
Orton, S., Coleman, T., Jones, L. L., Cooper, S., & Lewis, S. (2015). Smoking in the home after childbirth: prevalence and determinants in an English cohort. BMJ Open, 5(9), Article e008856. https://doi.org/10.1136/bmjopen-2015-008856

Objectives Children's exposure to secondhand smoke (SHS) is causally linked to childhood morbidity and mortality. Over 38% of English children (aged 4–15) whose parents are smokers are exposed to SHS in the home. Little is known about the prevale... Read More about Smoking in the home after childbirth: prevalence and determinants in an English cohort.

Changes in the rate of nicotine metabolism across pregnancy: a longitudinal study (2015)
Journal Article
Bowker, K., Lewis, S., Coleman, T., & Cooper, S. (2015). Changes in the rate of nicotine metabolism across pregnancy: a longitudinal study. Addiction, 110(11), https://doi.org/10.1111/add.13029

Aims: Increased nicotine metabolism during pregnancy could explain why nicotine replacement therapy (NRT) appears to be less effective on smoking cessation in pregnancy than in non-pregnant smokers, but little is known about nicotine metabolism acros... Read More about Changes in the rate of nicotine metabolism across pregnancy: a longitudinal study.

Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial (2015)
Journal Article
Cooper, S., Foster, K., Naughton, F., Leonardi-Bee, J., Sutton, S., Ussher, M., …Coleman, T. (2015). Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial. Trials, 16, Article 29. https://doi.org/10.1186/S13063-014-0546-4

Background Smoking in pregnancy is a public health problem. Self-help smoking cessation support can help pregnant women to stop smoking, but the effects of delivering this kind of support via SMS text message are not known. A previous randomised... Read More about Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial.

Cost-effectiveness of nicotine patches for smoking cessation in pregnancy: a placebo randomised controlled trial (SNAP) (2014)
Journal Article
Essex, H., Parrott, S., Wu, Q., Li, J., Cooper, S., & Coleman, T. (2014). Cost-effectiveness of nicotine patches for smoking cessation in pregnancy: a placebo randomised controlled trial (SNAP). Nicotine and Tobacco Research, https://doi.org/10.1093/ntr/ntu258

Introduction: Smoking during pregnancy is the most important, preventable cause of adverse pregnancy outcomes including miscarriage, premature birth and low birth weight, with huge financial costs to the NHS. However, there are very few published eco... Read More about Cost-effectiveness of nicotine patches for smoking cessation in pregnancy: a placebo randomised controlled trial (SNAP).

Predictors of children's secondhand smoke exposure at home: a systematic review and narrative synthesis of the evidence (2014)
Journal Article
Orton, S., Jones, L. L., Cooper, S., Lewis, S., & Coleman, T. (2014). Predictors of children's secondhand smoke exposure at home: a systematic review and narrative synthesis of the evidence. PLoS ONE, 9(11), Article e112690. https://doi.org/10.1371/journal.pone.0112690

BACKGROUND: Children's exposure to secondhand smoke (SHS) has been causally linked to a number of childhood morbidities and mortalities. Over 50% of UK children whose parents are smokers are regularly exposed to SHS at home. No previous review has id... Read More about Predictors of children's secondhand smoke exposure at home: a systematic review and narrative synthesis of the evidence.

Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial (2014)
Journal Article
Cooper, S., Taggar, J., Lewis, S., Marlow, N., Dickinson, A., Whitemore, R., & Coleman, T. (2014). Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial. Lancet Respiratory Medicine, 2(9), https://doi.org/10.1016/S2213-2600%2814%2970157-2

BACKGROUND: The SNAP (Smoking and Nicotine in Pregnancy) trial compared nicotine replacement therapy (NRT) patches with placebo in pregnant smokers; although NRT doubled cessation rates in the first 4 weeks, by delivery no differences in maternal sm... Read More about Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial.

The SNAP trial: A randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - Clinical effectiveness and safety until 2 years after delivery, with economic evaluation (2014)
Journal Article
Cooper, S., Lewis, S., Thornton, J., Marlow, N., Watts, K., Britton, J., …Coleman, T. (2014). The SNAP trial: A randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - Clinical effectiveness and safety until 2 years after delivery, with economic evaluation. Health Technology Assessment, 18(54), 1-128. https://doi.org/10.3310/hta18540

Background: Smoking during pregnancy causes many adverse pregnancy and birth outcomes. Nicotine replacement therapy (NRT) is effective for cessation outside pregnancy but efficacy and safety in pregnancy are unknown. We hypothesised that NRT would in... Read More about The SNAP trial: A randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - Clinical effectiveness and safety until 2 years after delivery, with economic evaluation.

Comparison of cotinine levels in pregnant women while smoking and when using nicotine replacement therapy (2014)
Journal Article
Bowker, K. A., Lewis, S., Coleman, T., Vaz, L. R., & Cooper, S. (2014). Comparison of cotinine levels in pregnant women while smoking and when using nicotine replacement therapy. Nicotine and Tobacco Research, 16(6), https://doi.org/10.1093/ntr/ntu029

BACKGROUND: Nicotine replacement therapy (NRT) helps smokers quit smoking, but trials indicate that there is no evidence that it is effective during pregnancy. As metabolism increases during pregnancy, NRT may deliver insufficient nicotine to allevia... Read More about Comparison of cotinine levels in pregnant women while smoking and when using nicotine replacement therapy.

Longitudinal cohort survey of women's smoking behaviour and attitudes in pregnancy: study methods and baseline data (2014)
Journal Article
Orton, S., Bowker, K., Cooper, S., Naughton, F., Ussher, M., Pickett, K. E., …Coleman, T. (2014). Longitudinal cohort survey of women's smoking behaviour and attitudes in pregnancy: study methods and baseline data. BMJ Open, 4(5), https://doi.org/10.1136/bmjopen-2014-004915

Objectives: To report methods used to assemble a contemporary pregnancy cohort for investigating influences on smoking behaviour before, during and after pregnancy and to report characteristics of women recruited. Design: Longitudinal cohort surve... Read More about Longitudinal cohort survey of women's smoking behaviour and attitudes in pregnancy: study methods and baseline data.

Nicotine dependence and biochemical exposure measures in the second trimester of pregnancy (2014)
Journal Article
Kwok, T. C., Taggar, J., Cooper, S., Lewis, S., & Coleman, T. (2014). Nicotine dependence and biochemical exposure measures in the second trimester of pregnancy. Nicotine and Tobacco Research, 16(2), https://doi.org/10.1093/ntr/ntt127

Introduction: The Heaviness of Smoking Index (HSI) is validated to measure nicotine dependence in nonpregnant smokers, and in these smokers, mean salivary and serum cotinine levels are related by a ratio of 1.25. However, as nicotine metabolism inc... Read More about Nicotine dependence and biochemical exposure measures in the second trimester of pregnancy.

Provision of smoking cessation support for pregnant women in England: results from an online survey of NHS stop smoking services for pregnant women (2014)
Journal Article
Fahy, S., Cooper, S., Coleman, T., Naughton, F., & Bauld, L. (2014). Provision of smoking cessation support for pregnant women in England: results from an online survey of NHS stop smoking services for pregnant women. BMC Health Services Research, 14(107), https://doi.org/10.1186/1472-6963-14-107

Background Smoking during pregnancy is a major public health concern and an NHS priority. In 2010, 26% of UK women smoked immediately before or during their pregnancy and 12% smoked continuously. Smoking cessation support is provided through free at... Read More about Provision of smoking cessation support for pregnant women in England: results from an online survey of NHS stop smoking services for pregnant women.

Factors Associated With Smoking Cessation in Early and Late Pregnancy in the Smoking, Nicotine, and Pregnancy Trial: A Trial of Nicotine Replacement Therapy (2013)
Journal Article
Vaz, L. R., Leonardi-Bee, J., Aveyard, P., Cooper, S., Grainge, M., & Coleman, T. (2014). Factors Associated With Smoking Cessation in Early and Late Pregnancy in the Smoking, Nicotine, and Pregnancy Trial: A Trial of Nicotine Replacement Therapy. Nicotine and Tobacco Research, 16(4), 381-389. https://doi.org/10.1093/ntr/ntt156

Introduction: Previous studies have found partners’ smoking status, multiparity, and nicotine dependence to be associated with smoking cessation in pregnancy. However, no studies have investigated influences on cessation among women using nicotine re... Read More about Factors Associated With Smoking Cessation in Early and Late Pregnancy in the Smoking, Nicotine, and Pregnancy Trial: A Trial of Nicotine Replacement Therapy.

Final Protocol and Statistical Analysis Plan for the SNAP Trial - a randomised, double-blind, placebo-controlled trial of nicotine replacement therapy in pregnancy
Other
Coleman, T., Cooper, S., Thornton, J., Britton, J., Lewis, S., Watts, K., …Grainge, M. J. Final Protocol and Statistical Analysis Plan for the SNAP Trial - a randomised, double-blind, placebo-controlled trial of nicotine replacement therapy in pregnancy

This NIHR HTA-funded smoking, nicotine and pregnancy (SNAP) trial investigated whether or not nicotine replacement therapy (NRT) is effective, cost-effective and safe when used for smoking cessation by pregnant women. We randomised 1050 women who wer... Read More about Final Protocol and Statistical Analysis Plan for the SNAP Trial - a randomised, double-blind, placebo-controlled trial of nicotine replacement therapy in pregnancy.