All Outputs (14)

The user experience of ecological momentary assessment and mood monitoring in Bipolar Disorder: a systematic review and meta-synthesis of qualitative studies (2025)
Journal Article
Astill Wright, L., Majid, M., Moore, M., Momoh, G., Patil, R., Shajan, G., Purewal, D., Patel, S., & Morriss, R. (in press). The user experience of ecological momentary assessment and mood monitoring in Bipolar Disorder: a systematic review and meta-synthesis of qualitative studies. Journal of Medical Internet Research, https://doi.org/10.2196/71525

Background:

The perspectives and preferences of individuals with Bipolar Disorder (BD) will likely be crucial for the success of mood monitoring interventions, or for Ecological Momentary Assessment (EMA) as a method of data collection. This resea... Read More about The user experience of ecological momentary assessment and mood monitoring in Bipolar Disorder: a systematic review and meta-synthesis of qualitative studies.

Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial (2025)
Journal Article
Nixon, E., Patel, S., Patel, P., Roe, J., Nixon, N., Sweeney, T., Bernard, P., Strauss, C., Craven, M., Malins, S., Goodwin, R., Astill Wright, L., Guo, B., & Morriss, R. (2025). Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial. JMIR Research Protocols, 14, Article e67695. https://doi.org/10.2196/67695

Background:

Recently published guidelines by the National Institute for Health and Care Excellence (NICE) have recommended both mindfulness-based and stress-reduction approaches as effective preventative mental wellbeing interventions for healthca... Read More about Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial.

Opportunities and challenges to delivering a trial for depressive symptoms in primary care during the COVID-19 pandemic: insights from the Alpha-Stim-D randomised controlled trial (2025)
Journal Article
Patel, S., Patel, P., Boutry, C., Guo, B., Butler, D., Higton, F., McNaughton, R., Briley, P. M., Griffiths, C., Nixon, N., Prasad, V., Sayal, K., Smart, D., Zafar, A., Kai, J., & Morriss, R. (2025). Opportunities and challenges to delivering a trial for depressive symptoms in primary care during the COVID-19 pandemic: insights from the Alpha-Stim-D randomised controlled trial. Trials, 26(1), Article 62. https://doi.org/10.1186/s13063-025-08772-3

Background: Randomised controlled trials (RCTs) are widely regarded as the most powerful research design for evidence-based practice. However, recruiting to RCTs can be challenging resulting in heightened costs and delays in research completion and i... Read More about Opportunities and challenges to delivering a trial for depressive symptoms in primary care during the COVID-19 pandemic: insights from the Alpha-Stim-D randomised controlled trial.

Data Integrity Issues With Web-Based Studies: An Institutional Example of a Widespread Challenge (2024)
Journal Article
French, B., Babbage, C., Bird, K., Marsh, L., Patel, S., Pelton, M., Cassidy, S., & Rennick-Egglestone, S. (2024). Data Integrity Issues With Web-Based Studies: An Institutional Example of a Widespread Challenge. JMIR Mental Health, 11, Article e58432. https://doi.org/10.2196/58432

This paper reports on the growing issues experienced when conducting web-based–based research. Nongenuine participants, repeat responders, and misrepresentation are common issues in health research posing significant challenges to data integrity. A s... Read More about Data Integrity Issues With Web-Based Studies: An Institutional Example of a Widespread Challenge.

Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial (2023)
Journal Article
Morriss, R., Patel, S., Boutry, C., Patel, P., Guo, B., Briley, P. M., Butler, D., Craven, M., Duncan, A., Griffiths, C., Higton, F., McNaughton, R., Nixon, N., Prasad, V., Sayal, K., Smart, D., Zafar, A., & Kai, J. (2023). Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial. Lancet Psychiatry, 10(3), 172-183. https://doi.org/10.1016/S2215-0366%2823%2900007-X

Background: Randomised sham-controlled trials of cranial electrostimulation with the Alpha-Stim Anxiety Insomnia and Depression (AID) device have reported improved anxiety and depression symptoms; however, no adequately powered sham-controlled trials... Read More about Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial.

A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial) (2022)
Journal Article
Patel, S., Boutry, C., Patel, P., Craven, M. P., Guo, B., Zafar, A., Kai, J., Smart, D., Butler, D., Higton, F., McNaughton, R., Briley, P. M., Griffiths, C., Nixon, N., Sayal, K., & Morriss, R. (2022). A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial). Trials, 23(1), Article 250. https://doi.org/10.1186/s13063-022-06192-1

Background: Major depression is the second leading cause of years lost to disability worldwide and is a leading contributor to suicide. However, first-line antidepressants are only fully effective for 33%, and only 40% of those offered psychological... Read More about A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial).

Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study (2020)
Journal Article
Aldridge, Z., Patel, S., Guo, B., Nixon, E., Bouman, W. P., Witcomb, G. L., & Arcelus, J. (2021). Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study. Andrology, 9(6), 1808-1816. https://doi.org/10.1111/andr.12884

Background
Cross-sectional studies show that transgender people are more likely than cisgender people to experience depression and anxiety before Gender Affirming Hormone Treatment (GAHT). However, the effect of GAHT on mental health in transgender... Read More about Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study.

Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study (2020)
Journal Article
Aldridge, Z., Patel, S., Guo, B., Nixon, E., Pierre Bouman, W., Witcomb, G. L., & Arcelus, J. (2021). Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study. Andrology, 9(6), 1808-1816. https://doi.org/10.1111/andr.12884

Background

Cross‐sectional studies show that transgender people are more likely than cisgender people to experience depression and anxiety before Gender Affirming Hormone Treatment (GAHT). However, the effect of GAHT on mental health in transgende... Read More about Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study.

The Acceptability and Usability of Digital Health Interventions for Adults with Depressive, Anxiety and Somatoform Disorders: A Qualitative Systematic Review and Meta-synthesis (2020)
Journal Article
Patel, S., Akhtar, A., Malins, S., Wright, N., Rowley, E., Young, E., Sampson, S., & Morriss, R. (2020). The Acceptability and Usability of Digital Health Interventions for Adults with Depressive, Anxiety and Somatoform Disorders: A Qualitative Systematic Review and Meta-synthesis. Journal of Medical Internet Research, 22(7), Article e16228. https://doi.org/10.2196/16228

Background: The prevalence of mental health disorders continues to rise, with almost 4% of the world population having an anxiety disorder and almost 3.5% having depression in 2017. Despite the high prevalence, only one-third of people with depressio... Read More about The Acceptability and Usability of Digital Health Interventions for Adults with Depressive, Anxiety and Somatoform Disorders: A Qualitative Systematic Review and Meta-synthesis.

Clinical and economic outcomes of remotely delivered cognitive behaviour therapy versus treatment as usual for repeat unscheduled care users with severe health anxiety: a multi-centre randomised controlled trial (2019)
Journal Article
Morriss, R., Patel, S., Mallins, S., Guo, B., Higton, F., James, M., Wu, M., Brown, P., Boycott, N., Kaylor-Hughes, C., Morris, M., Rowley, E., Simpson, J., Smart, D., Stubley, M., Kai, J., & Tyrer, H. (2019). Clinical and economic outcomes of remotely delivered cognitive behaviour therapy versus treatment as usual for repeat unscheduled care users with severe health anxiety: a multi-centre randomised controlled trial. BMC Medicine, 17, 1-13. https://doi.org/10.1186/s12916-019-1253-5

Background: Repeat users of unscheduled health care with severe health anxiety are challenging to engage in psychological help and incur high service costs. We investigated whether clinical and economic outcomes were improved by offering remote cogni... Read More about Clinical and economic outcomes of remotely delivered cognitive behaviour therapy versus treatment as usual for repeat unscheduled care users with severe health anxiety: a multi-centre randomised controlled trial.

Cognitive behaviour therapy for long-term frequent attenders in primary care: a feasibility case series and treatment development study (2016)
Journal Article
Malins, S., Kai, J., Atha, C., Avery, A., Guo, B., James, M., Patel, S., Sampson, C., Stubley, M., & Morriss, R. K. (2016). Cognitive behaviour therapy for long-term frequent attenders in primary care: a feasibility case series and treatment development study. British Journal of General Practice, 66(651), e729-e736. https://doi.org/10.3399/bjgp16X686569

Background: Most frequent attendance in primary care is temporary. Long-term frequent attendance may be suitable for psychological intervention to address health management and service use.

Aim: To explore the feasibility and acceptability of cog... Read More about Cognitive behaviour therapy for long-term frequent attenders in primary care: a feasibility case series and treatment development study.

Protocol investigating the clinical outcomes and cost-effectiveness of cognitive–behavioural therapy delivered remotely for unscheduled care users with health anxiety: randomised controlled trial (2016)
Journal Article
Patel, S., Malins, S., Guo, B., James, M., Kai, J., Kaylor-Hughes, C., Rowley, E., Simpson, J., Smart, D., Stubley, M., Tyrer, H., & Morriss, R. K. (2016). Protocol investigating the clinical outcomes and cost-effectiveness of cognitive–behavioural therapy delivered remotely for unscheduled care users with health anxiety: randomised controlled trial. BJPsych Open, 2, https://doi.org/10.1192/bjpo.bp.115.002220

Background
Health anxiety and medically unexplained symptoms cost the National Health Service (NHS) an estimated £3 billion per year in unnecessary costs with little evidence of patient benefit. Effective treatment is rarely taken up due to issues s... Read More about Protocol investigating the clinical outcomes and cost-effectiveness of cognitive–behavioural therapy delivered remotely for unscheduled care users with health anxiety: randomised controlled trial.

Clinical characteristics of persistent frequent attenders in primary care: case–control study (2015)
Journal Article
Patel, S., Kai, J., Atha, C., Avery, A., Guo, B., James, M., Malins, S., Sampson, C., Stubley, M., & Morriss, R. (2015). Clinical characteristics of persistent frequent attenders in primary care: case–control study. Family Practice, cmv076. https://doi.org/10.1093/fampra/cmv076

Background. Most frequent attendance in primary care is temporary, but persistent frequent attendance is expensive and may be suitable for psychological intervention. To plan appropriate intervention and service delivery, there is a need for research... Read More about Clinical characteristics of persistent frequent attenders in primary care: case–control study.

Persistent frequent attenders in primary care: costs, reasons for attendance, organisation of care and potential for cognitive behavioural therapeutic intervention (2012)
Journal Article
Morriss, R. K., Kai, J., Atha, C., Avery, A., Bayes, S., Franklin, M., George, T., James, M., Malins, S., McDonald, R., Patel, S., Stubley, M., & Yang, M. (2012). Persistent frequent attenders in primary care: costs, reasons for attendance, organisation of care and potential for cognitive behavioural therapeutic intervention. BMC Family Practice, 13(39), https://doi.org/10.1186/1471-2296-13-39

Background:

The top 3% of frequent attendance in primary care is associated with 15% of all appointments in primary care, a fivefold increase in hospital expenditure, and more mental disorder and functional somatic symptoms compared to normal atte... Read More about Persistent frequent attenders in primary care: costs, reasons for attendance, organisation of care and potential for cognitive behavioural therapeutic intervention.