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All Outputs (20)

Identification of key symptoms for a core outcome set for research in vulvar lichen sclerosus: a CORALS symptom domain initiative (2025)
Journal Article
Foster, E. L., Davis, M. I., Li, A. X., Kottner, J., Thomas, K. S., Simpson, R., & Leclair, C. M. (in press). Identification of key symptoms for a core outcome set for research in vulvar lichen sclerosus: a CORALS symptom domain initiative. British Journal of Dermatology,

Background:
Genital lichen sclerosus (LS) is a chronic inflammatory skin disease affecting men, women and children. It is most common in females with estimated 1-3% of women affected across their lifetimes. Vulvar LS can cause significant symptoms... Read More about Identification of key symptoms for a core outcome set for research in vulvar lichen sclerosus: a CORALS symptom domain initiative.

Using a novel smartphone app to track noise and vibration exposure during neonatal ambulance transport (2025)
Journal Article
Partridge, T., Leslie, A., Mistry, A., Simpson, R. B., Morris, D. E., McNally, D., Crowe, J., & Sharkey, D. (2025). Using a novel smartphone app to track noise and vibration exposure during neonatal ambulance transport. Archives of Disease in Childhood. Fetal and Neonatal Edition, 110(4), 395-400. https://doi.org/10.1136/archdischild-2024-327758

Objective To assess the utility of a bespoke smartphone app to map noise and vibration exposure across neonatal road ambulance journeys.

Design and setting Prospective observational study of ambulance journeys across a large UK neonatal transport... Read More about Using a novel smartphone app to track noise and vibration exposure during neonatal ambulance transport.

Barriers to diagnosing and treating vulval lichen sclerosus: a survey study (2024)
Journal Article
Crew, A., Leatherland, R., Clarke, L., Owen, C., & Simpson, R. C. (2025). Barriers to diagnosing and treating vulval lichen sclerosus: a survey study. British Journal of General Practice, 75(753), e250-e256. https://doi.org/10.3399/BJGP.2024.0360

Background

Vulval lichen sclerosus (VLS) is a chronic inflammatory condition that is frequently misdiagnosed and under-recognised. To date, qualitative research has focused on lived experience of VLS, with women attributing diagnostic delay to po... Read More about Barriers to diagnosing and treating vulval lichen sclerosus: a survey study.

A cross‐sectional study of the vulval dermatology clinic population over a 4‐year period and development of a national vulval disease database (2024)
Journal Article
de Brito, M., Kirby, L., Lomas, K., Javed, A., Owen, C., & Simpson, R. (2024). A cross‐sectional study of the vulval dermatology clinic population over a 4‐year period and development of a national vulval disease database. Skin Health and Disease, 4(6), Article ski2.446. https://doi.org/10.1002/ski2.446

Background
Vulval disease significantly impacts quality of life but is historically under-researched. The epidemiology and aetiology of many vulval conditions is unclear. Data to optimise patient care are lacking.

Objectives
To describe the popu... Read More about A cross‐sectional study of the vulval dermatology clinic population over a 4‐year period and development of a national vulval disease database.

Expert opinion on characteristics of vulval lichen sclerosus: initial identification of important clinical features through an international electronic Delphi consensus study (2024)
Journal Article
Simpson, R. C., Birchall, M., Daniels, J., Gran, S., Kirtschig, G., & Thomas, K. S. (2025). Expert opinion on characteristics of vulval lichen sclerosus: initial identification of important clinical features through an international electronic Delphi consensus study. Clinical and Experimental Dermatology, 50(3), 590-596. https://doi.org/10.1093/ced/llae393

Background Lichen sclerosus (LS) is a chronic inflammatory condition that mainly affects genital skin. It causes distressing symptoms that impact daily quality of life, as well as progressive anatomical changes and a potential risk of cancer. Vulval... Read More about Expert opinion on characteristics of vulval lichen sclerosus: initial identification of important clinical features through an international electronic Delphi consensus study.

P078 Establishing diagnostic criteria for vulval lichen sclerosus (SHELLS): an international electronic-Delphi consensus study (2024)
Journal Article
Simpson, R., Birchall, M., Daniels, J., Gran, S., Kirtschig, G., & Thomas, K. (2024). P078 Establishing diagnostic criteria for vulval lichen sclerosus (SHELLS): an international electronic-Delphi consensus study. British Journal of Dermatology, 191(Supplement_1), i51-i51. https://doi.org/10.1093/bjd/ljae090.105

Lichen sclerosus (LS) is a chronic inflammatory condition mainly affecting genital skin. It causes distressing symptoms that impact daily quality of life, results in progressive anatomical changes and has a potential risk of cancer. There is no defin... Read More about P078 Establishing diagnostic criteria for vulval lichen sclerosus (SHELLS): an international electronic-Delphi consensus study.

EuroGuiderm guideline on lichen sclerosus-Treatment of lichen sclerosus. (2024)
Journal Article
Kirtschig, G., Kinberger, M., Kreuter, A., Simpson, R., Günthert, A., van Hees, C., Becker, K., Ramakers, M., Corazza, M., Müller, S., von Seitzberg, S., Boffa, M., Stein, R., Barbagli, G., Chi, C., Dauendorffer, J., Fischer, B., Gaskins, M., Hiltunen-Back, E., Höfinger, A., …Werner, R. (2024). EuroGuiderm guideline on lichen sclerosus-Treatment of lichen sclerosus. Journal of the European Academy of Dermatology and Venereology, 38(10), 1874-1909. https://doi.org/10.1111/jdv.20083

Introduction
Lichen sclerosus (LS) is an inflammatory skin disease affecting all ages. LS typically involves the anogenital site where it causes itching and soreness; it may lead to sexual and urinary dysfunction in females and males; however, it ma... Read More about EuroGuiderm guideline on lichen sclerosus-Treatment of lichen sclerosus..

The critical role of technologies in neonatal care (2023)
Journal Article
Taha, S., Simpson, R. B., & Sharkey, D. (2023). The critical role of technologies in neonatal care. Early Human Development, 187, Article 105898. https://doi.org/10.1016/j.earlhumdev.2023.105898

Neonatal care has made significant advances in the last few decades. As a result, mortality and morbidity in high-risk infants, such as extremely preterm infants or those infants with birth-related brain injury, has reduced significantly. Many of the... Read More about The critical role of technologies in neonatal care.

Core outcome domains for lichen sclerosus: a CORALS initiative consensus statement (2023)
Journal Article
Simpson, R. C., Kirtschig, G., Selk, A., von Seitzberg, S., Vittrup, G., Bissonnette, I., Kottner, J., Lanthier, J., Stanton, C., Foster, D., Promm, M., Augenti, A., Lauretti, S., Thomas, K. S., & The Core Outcomes for Research in Lichen Sclerosus (CORALS) initiative steering group. (2023). Core outcome domains for lichen sclerosus: a CORALS initiative consensus statement. British Journal of Dermatology, 188(5), 628–635. https://doi.org/10.1093/bjd/ljac145

Background
Lichen sclerosus (LS) is a chronic inflammatory condition mainly affecting genital skin. It causes distressing symptoms that impact daily quality of life (QoL). It causes progressive anatomical changes and a potential risk of cancer. Publ... Read More about Core outcome domains for lichen sclerosus: a CORALS initiative consensus statement.

Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base (2021)
Journal Article
Tasker, F., Kirby, L., Grindlay, D. J. C., Lewis, F., & Simpson, R. C. (2021). Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base. Skin Health and Disease, 1(3), Article e52. https://doi.org/10.1002/ski2.52

Background

Lichen sclerosus (LS) is a chronic, inflammatory dermatosis. Initial treatment with superpotent topical corticosteroids is the accepted and evidence-based first-line therapy. For those who do not respond after exclusion of other potenti... Read More about Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base.

Is urinary incontinence associated with vulval lichen sclerosus in females? A cross‐sectional study (2021)
Journal Article
Kirby, L., Gran, S., Orekoya, F., Owen, C., & Simpson, R. (2021). Is urinary incontinence associated with vulval lichen sclerosus in females? A cross‐sectional study. British Journal of Dermatology, 185(5), 1063-1065. https://doi.org/10.1111/bjd.20583

Increasing evidence suggests the pathogenesis of male genital lichen sclerosus (LS) is driven by chronic, occluded exposure of susceptible epithelium to the irritant effect of urine (1, 2). It is not clear how this can be extrapolated to females, how... Read More about Is urinary incontinence associated with vulval lichen sclerosus in females? A cross‐sectional study.

Is urinary incontinence associated with lichen sclerosus in females? A systematic review and meta‐analysis (2021)
Journal Article
Kirby, L., Gran, S., Kreuser-Genis, I., Owen, C., & Simpson, R. (2021). Is urinary incontinence associated with lichen sclerosus in females? A systematic review and meta‐analysis. Skin Health and Disease, 1(1), Article e13. https://doi.org/10.1002/ski2.13

Background
Lichen sclerosus (LS) is a scarring chronic inflammatory disease with a predilection for genital skin in both sexes. The aetiology of LS is controversial, but evidence increasingly suggests that the occluded exposure of susceptible epith... Read More about Is urinary incontinence associated with lichen sclerosus in females? A systematic review and meta‐analysis.

Outcome domains in lichen sclerosus (2020)
Journal Article
Goodrum, C., Leighton, P., & Simpson, R. (2020). Outcome domains in lichen sclerosus. British Journal of Dermatology, 183(5), 966-968. https://doi.org/10.1111/bjd.19253

Lichen Sclerosus (LS) is a chronic inflammatory dermatosis predominantly affecting the genitals. It can affect men, women and children. LS affecting female genitalia typically presents with itchy patches that impact on physical and psychosocial‐sexua... Read More about Outcome domains in lichen sclerosus.

Benign skin diseases affecting the vulva (2019)
Journal Article
Kirby, L., Simpson, R., & Nunns, D. (2019). Benign skin diseases affecting the vulva. Obstetrics, Gynaecology and Reproductive Medicine, 29(9), 264-270. https://doi.org/10.1016/j.ogrm.2019.05.004

Vulval skin disease is common in gynaecological practice. This review aims to enhance clinical skills in patient assessment, vulval examination and treatment of common benign vulval skin disease illustrated through cases. Although simple treatments a... Read More about Benign skin diseases affecting the vulva.

Living with vulval lichen sclerosus: a systematic review (2019)
Journal Article
Rees, S., Kirby, L., & Simpson, R. (2019). Living with vulval lichen sclerosus: a systematic review. British Journal of Dermatology, 180(6), 1555-1556. https://doi.org/10.1111/bjd.17790

Lichen sclerosus (LS) is an under‐researched disorder, particularly from the perspective of individuals who have the condition. A recent James Lind Alliance Priority Setting Partnership identified uncertainties in many aspects of the condition, inclu... Read More about Living with vulval lichen sclerosus: a systematic review.

Future research priorities for lichen sclerosus – results of a James Lind Alliance Priority Setting Partnership (2019)
Journal Article
Simpson, R., Cooper, S., Kirtschig, G., Larsen, S., Lawton, S., McPhee, M., Murphy, R., Nunns, D., Rees, S., Tarpey, M., Thomas, K., & Lichen Sclerosus Priority Setting Partnership Steering Group. (2019). Future research priorities for lichen sclerosus – results of a James Lind Alliance Priority Setting Partnership. British Journal of Dermatology, 180(5), 1236-1237. https://doi.org/10.1111/bjd.17447

Help for Future Research: Lessons Learned in Trial Design, Recruitment, and Delivery From the “hELP” Study (2018)
Journal Article
Simpson, R. C., Murphy, R., Bratton, D. J., Sydes, M. R., Wilkes, S., Nankervis, H., Dowey, S., Bell, H., Cruickshank, M. E., Gibbon, K., Green, C. M., Wong, C., Owen, C. M., London, K., Haque, S., & Thomas, K. S. (2018). Help for Future Research: Lessons Learned in Trial Design, Recruitment, and Delivery From the “hELP” Study. Journal of Lower Genital Tract Disease, 22(4), 405-408. https://doi.org/10.1097/LGT.0000000000000407

Skin diseases affecting the vulva (2017)
Journal Article
Simpson, R., & Nunns, D. (2017). Skin diseases affecting the vulva. Obstetrics, Gynaecology and Reproductive Medicine, 27(3), 77-85. https://doi.org/10.1016/j.ogrm.2016.12.007

Vulval skin disease is common in gynaecological practice. This article aims to enhance clinical skills in patient assessment, vulval examination and treatment of common benign vulval skin disease. Basic treatments are often of benefit the patient (e.... Read More about Skin diseases affecting the vulva.