All Outputs (2)

Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem (2012)
Journal Article
Beale, K., Gardiner, J., Bewick, G., Hostomska, K., Patel, N., Hussain, S., Jayasena, C., Ebling, F., Jethwa, P., Prosser, H., Lattanzi, R., Negri, L., Ghatei, M., Bloom, S., & Dhillo, W. (2013). Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem. British Journal of Pharmacology, 168(2), 403-410. https://doi.org/10.1111/j.1476-5381.2012.02191.x

Background and Purpose Prokineticin 2 (PK2) has recently been shown to acutely reduce food intake in rodents. We aimed to determine the CNS sites and receptors that mediate the anorectic effects of peripherally administered PK2 and its chronic effect... Read More about Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem.

Effects of manipulating hypothalamic triiodothyronine concentrations on seasonal body weight and torpor cycles in Siberian hamsters (2012)
Journal Article
Murphy, M., Jethwa, P. H., Warner, A., Barrett, P., Nilaweera, K. N., Brameld, J. M., & Ebling, F. J. (2012). Effects of manipulating hypothalamic triiodothyronine concentrations on seasonal body weight and torpor cycles in Siberian hamsters. Endocrinology, 153(1), 101-112. https://doi.org/10.1210/en.2011-1249

Siberian hamsters display photoperiodically regulated annual cycles in body weight, appetite, and reproduction. Previous studies have revealed a profound up-regulation of type 3 deiodinase (DIO3) mRNA in the ventral ependyma of the hypothalamus assoc... Read More about Effects of manipulating hypothalamic triiodothyronine concentrations on seasonal body weight and torpor cycles in Siberian hamsters.