All Outputs (4)

Oral vaccination with a rough attenuated mutant of S. Infantis increases post-wean weight gain and prevents clinical signs of salmonellosis in S. Typhimurium challenged pigs (2015)
Journal Article
Foster, N., Richards, L., Higgins, J., Kanellos, T., & Barrow, P. (2016). Oral vaccination with a rough attenuated mutant of S. Infantis increases post-wean weight gain and prevents clinical signs of salmonellosis in S. Typhimurium challenged pigs. Research in Veterinary Science, 104, https://doi.org/10.1016/j.rvsc.2015.12.013

We show that oral inoculation of 14 day old conventional piglets with a rough attenuated Salmonella enterica serovar Infantis 1326/28?r (serogroup C1), 24 h prior to oral challenge with S. enterica serovar Typhimurium 4/74 (serogroup B), resulted in... Read More about Oral vaccination with a rough attenuated mutant of S. Infantis increases post-wean weight gain and prevents clinical signs of salmonellosis in S. Typhimurium challenged pigs.

Vasoactive intestinal peptide (VIP) differentially affects inflammatory immune responses in human monocytes infected with viable Salmonella or stimulated with LPS (2015)
Journal Article
Askar, B. A., Ibrahim, H., Barrow, P., & Foster, N. (2015). Vasoactive intestinal peptide (VIP) differentially affects inflammatory immune responses in human monocytes infected with viable Salmonella or stimulated with LPS. Peptides, 71, https://doi.org/10.1016/j.peptides.2015.06.009

We compared the effect of VIP on human blood monocytes infected with Salmonella typhimurium 4/74 or stimulated with LPS. VIP (10?7 M) increased monocyte viability by 24% and 9% when cultured for 24 h with 4/74 or Salmonella LPS (100 ng/ml), respectiv... Read More about Vasoactive intestinal peptide (VIP) differentially affects inflammatory immune responses in human monocytes infected with viable Salmonella or stimulated with LPS.

Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species (2015)
Journal Article
Giles, T., Yon, L., Hannant, D., Barrow, P., & Abu-Median, A. (2015). Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species. Molecular and Cellular Probes, 29(6), https://doi.org/10.1016/j.mcp.2015.07.005

The demand for diagnostic tools that allow simultaneous screening of samples for multiple pathogens is increasing because they overcome the limitations of other methods, which can only screen for a single or a few pathogens at a time. Microarrays off... Read More about Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species.

IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c (2015)
Journal Article
Higgins, J., Mutamba, S., Mahida, Y. R., Barrow, P., & Foster, N. (2015). IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c. Human Immunology, 76(4), https://doi.org/10.1016/j.humimm.2015.01.012

We show that IL-36? induced maturation of human MDDCs and stimulated differentiation of IFN-? producing (Type 1) CD3+ lymphocytes but was not as effective as IL-36? in doing so. For the first time, we also show that IL-36? induced expression of CD14... Read More about IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c.