All Outputs (89)

What Works Well for People With Dementia and Their Supporters From South Asian, African and Caribbean Communities in the UK: A Narrative Synthesis Systematic Review and Expert Consultations (2025)
Journal Article
Mcdermott, O., Sobers, T., Mukadam, N., Lee, A. R., & Orrell, M. (2025). What Works Well for People With Dementia and Their Supporters From South Asian, African and Caribbean Communities in the UK: A Narrative Synthesis Systematic Review and Expert Consultations. International Journal of Geriatric Psychiatry, 40(3), Article e70047. https://doi.org/10.1002/gps.70047

Objectives
This review aims to synthesise the evidence regarding the use and provision of dementia services and support for people with dementia and/or supporters from South Asian, African or Caribbean back grounds living in the UK.

Methods
A na... Read More about What Works Well for People With Dementia and Their Supporters From South Asian, African and Caribbean Communities in the UK: A Narrative Synthesis Systematic Review and Expert Consultations.

The Development of the Person Attuned Musical Interactions - Modified Version (PAMI-M) for UK Care Home Staff Working with Residents with Dementia (2025)
Journal Article
Waters-Harvey, B., Mette Ridder, H., Kolbe Krøier, J., Orrell, M., & McDermott, O. (in press). The Development of the Person Attuned Musical Interactions - Modified Version (PAMI-M) for UK Care Home Staff Working with Residents with Dementia. Nordic Journal of Music Therapy,

The usability and feasibility of the Person Attuned Musical Interactions intervention – modified version (PAMI-M) for UK care home staff working with residents with dementia (2025)
Journal Article
Waters, B., Schneible, B., Orrell, M., Fothergill, R., & McDermott, O. (2025). The usability and feasibility of the Person Attuned Musical Interactions intervention – modified version (PAMI-M) for UK care home staff working with residents with dementia. Nordic Journal of Music Therapy, 1-21. https://doi.org/10.1080/08098131.2025.2461313

Introduction
Research on music interventions in care homes to improve social interactions has shown inconsistent results, potentially due to insufficient guidelines and staff training. Person Attuned Musical Interactions (PAMI), an evidence-based mu... Read More about The usability and feasibility of the Person Attuned Musical Interactions intervention – modified version (PAMI-M) for UK care home staff working with residents with dementia.

Risk of dementia associated with anticholinergic drugs for overactive bladder in adults aged ≥55 years: nested case-control study (2024)
Journal Article
Iyen, B., Coupland, C., Bell, B., Orrell, M., Dening, T., & Avery, T. (2024). Risk of dementia associated with anticholinergic drugs for overactive bladder in adults aged ≥55 years: nested case-control study. BMJ Medicine, 3(1), Article e000799. https://doi.org/10.1136/bmjmed-2023-000799

Objective To investigate whether different anticholinergic drug treatments for overactive bladder have differential risks for incident dementia, in a large representative population of older adults in England.

Design Nested case-control study.... Read More about Risk of dementia associated with anticholinergic drugs for overactive bladder in adults aged ≥55 years: nested case-control study.

Development of a Best Practice Guidance on Online Peer Support for People with Young-Onset Dementia (2024)
Journal Article
Loseto-Gerritzen, E. V., McDermott, O., & Orrell, M. (2024). Development of a Best Practice Guidance on Online Peer Support for People with Young-Onset Dementia. Behavioral Sciences, 14(9), Article 746. https://doi.org/10.3390/bs14090746

This work aimed to develop a Best Practice Guidance on online peer support for people with young-onset dementia (YOD). The Best Practice Guidance was developed through a systematic literature review, focus groups, an online survey, and interviews and... Read More about Development of a Best Practice Guidance on Online Peer Support for People with Young-Onset Dementia.

The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact (2024)
Journal Article
Kalaria, R., Maestre, G., Mahinrad, S., Acosta, D. M., Akinyemi, R. O., Alladi, S., Allegri, R. F., Arshad, F., Babalola, D. O., Baiyewu, O., Bak, T. H., Bellaj, T., Brodie‐Mends, D. K., Carrillo, M. C., Celestin, K., Damasceno, A., de Silva, R. K., de Silva, R., Djibuti, M., Dreyer, A. J., …Ismail, O. (2024). The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(6), 4290-4314. https://doi.org/10.1002/alz.13836

Two of every three persons living with dementia reside in low‐ and middle‐income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs oc... Read More about The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact.

EmpRess: an eHealth implementation readiness checklist for dementia developed through an interview study of stakeholder needs (2024)
Journal Article
Christie, H. L., Atefi, G., Craven, M. P., Orrell, M., & de Vugt, M. E. (2024). EmpRess: an eHealth implementation readiness checklist for dementia developed through an interview study of stakeholder needs. Aging and Mental Health, 28(5), 791-800. https://doi.org/10.1080/13607863.2024.2323951

Objective
This study aimed to create a tool to assess eHealth interventions for dementia by adapting an existing implementation readiness (ImpRess) checklist that assessed manualised interventions.

Methods
In Part 1, online semi-structured inter... Read More about EmpRess: an eHealth implementation readiness checklist for dementia developed through an interview study of stakeholder needs.

Online peer support for people with Amyotrophic Lateral Sclerosis (ALS): a narrative synthesis systematic review (2024)
Journal Article
Gerritzen, E. V., Lee, A. R., McDermott, O., Coulson, N., & Orrell, M. (2024). Online peer support for people with Amyotrophic Lateral Sclerosis (ALS): a narrative synthesis systematic review. Frontiers in Digital Health, 6, Article 1138530. https://doi.org/10.3389/fdgth.2024.1138530

Background: Amyotrophic Lateral Sclerosis (ALS) significantly impacts the lives of people with the diagnosis and their families. A supportive social environment is important for people with ALS to adopt effective coping strategies and health behaviou... Read More about Online peer support for people with Amyotrophic Lateral Sclerosis (ALS): a narrative synthesis systematic review.

Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist (2023)
Presentation / Conference Contribution
Christie, H. L., Atefi, G. L., Craven, M. P., Orrell, M., & de Vugt, M. E. (2023, October). Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist. Poster presented at 33rd Alzheimer Europe Conference, Helsinki, Finland

Situation: eHealth interventions are a possible solution for rising dementia care costs and potential negative effects on carers

Problem: Few evidence-based eHealth interventions are implemented in practice

Solution :
Adapt existing implementa... Read More about Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist.

Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial (2023)
Journal Article
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., Hoare, Z., Hancox, J., Bajwa, R., Burgon, C., Howe, L., Cowley, A., Bramley, T., Long, A., Lock, J., Tucker, R., Adams, E. J., O’Brien, R., Kearney, F., Kowalewska, K., …Masud, T. (2023). Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial. BMJ, 382, Article e074787. https://doi.org/10.1136/bmj-2023-074787

Objective To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared with usual care.

Design Randomised controlled trial.

Setting Participants’... Read More about Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial.

A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach (2023)
Journal Article
Leung, P., Orrell, M., Yates, L., & Orgeta, V. (2023). A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach. International Journal of Geriatric Psychiatry, 38(7), Article e5945. https://doi.org/10.1002/gps.5945

Objectives: This study aimed to investigate the mediating effects of quality of the caregiving relationship and other carer and person with dementia variables in predicting carer resilience over time. Method: Carers of people with mild and moderate d... Read More about A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach.

Community Occupational Therapy in Dementia intervention for people with mild to moderate dementia and their family carers in the UK: the VALID research programme including RCT (2023)
Journal Article
Wenborn, J., Mountain, G., Moniz-Cook, E., Poland, F., King, M., Omar, R., O’Keeffe, A., Morris, S., Pizzo, E., Michie, S., Vernooij-Dassen, M., Graff, M., Hill, J., Challis, D., Russell, I., Sackley, C., Hynes, S., Crellin, N., Mundy, J., Burgess, J., …Orrell, M. (2023). Community Occupational Therapy in Dementia intervention for people with mild to moderate dementia and their family carers in the UK: the VALID research programme including RCT. Programme Grants for Applied Research, 11(5), 1-76. https://doi.org/10.3310/rgtj7429

Background

People with dementia find it increasingly difficult to carry out daily activities (activities of daily living), and may require increasing support from family carers. Researchers in the Netherlands developed the Community Occupational T... Read More about Community Occupational Therapy in Dementia intervention for people with mild to moderate dementia and their family carers in the UK: the VALID research programme including RCT.

Online peer support: views and experiences of people with young onset dementia (YOD) (2023)
Journal Article
Gerritzen, E. V., McDermott, O., & Orrell, M. (2023). Online peer support: views and experiences of people with young onset dementia (YOD). Aging and Mental Health, 27(12), 2386-2394. https://doi.org/10.1080/13607863.2023.2205833

Objectives: This study explores (1) which platforms people with YOD use for online peer support, (2) reasons for using or not using online peer support, and (3) how to optimise potential benefits and accessibility. Methods: A mixed-methods online sur... Read More about Online peer support: views and experiences of people with young onset dementia (YOD).

Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial (2023)
Preprint / Working Paper
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., Hoare, Z., Hancox, J., Bajwa, R., Burgon, C., Howe, L., Cowley, A., Bramley, T., Long, A., Lock, J., Tucker, R., Adams, E., O’Brien, R., Kearney, F., Kowalewska, K., …Masud, T. Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial

Background Dementia is associated with frailty leading to increased risks of falls and hospitalisations. Interventions are required to maintain functional ability, strength and balance.

Design Multi-centre parallel group randomised controlled tria... Read More about Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial.

Dementia and hearing-aid use: a two-way street (2022)
Journal Article
Naylor, G., Dillard, L., Orrell, M., Stephan, B. C. M., Zobay, O., & Saunders, G. H. (2022). Dementia and hearing-aid use: a two-way street. Age and Ageing, 51(12), Article afac266. https://doi.org/10.1093/ageing/afac266

Objectives
Hearing-aid use may reduce risk of dementia, but cognitive impairment makes use more challenging. An observed association between reduced hearing-aid use and incident dementia could reflect either or both of these causal paths. The object... Read More about Dementia and hearing-aid use: a two-way street.

Participatory visual arts activities for people with dementia: a review (2022)
Book Chapter
Barroso, A. C., Rai, H. K., Sousa, L., Orrell, M., & Schneider, J. (2022). Participatory visual arts activities for people with dementia: a review. In M. Orrell, D. Oliveira, O. McDermott, F. R. Verhey, F. C. Dassen, & R.-M. Dröes (Eds.), Improving the Lives of People with Dementia through Technology: Interdisciplinary Network for Dementia Utilising Current Technology (100-126). Routledge. https://doi.org/10.4324/9781003289005-11

The aims of this review were to report and summarise the effects of interventions using participatory visual arts activities in dementia research through a narrative synthesis systematic review. We searched four databases MEDLINE, EMBASE, PsycINFO an... Read More about Participatory visual arts activities for people with dementia: a review.

Thinkability: A new app for cognitive stimulation for people with dementia (2022)
Book Chapter
Rai, H. K., Schneider, J., & Orrell, M. (2022). Thinkability: A new app for cognitive stimulation for people with dementia. In M. Orrell, D. Oliveira, O. McDermott, F. R. Verhey, F. C. Dassen, & R.-M. Dröes (Eds.), Improving the Lives of People with Dementia through Technology: Interdisciplinary Network for Dementia Utilising Current Technology (86-99). Routledge. https://doi.org/10.4324/9781003289005-10

People with dementia benefit from activities that stimulate their cognition, and there is evidence that carers can benefit too. Among psychosocial interventions to help this group, cognitive stimulation therapy (CST) is well established as the treatm... Read More about Thinkability: A new app for cognitive stimulation for people with dementia.

A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes (2022)
Journal Article
Thelu, M., Webster, B., Jones, K., & Orrell, M. (2022). A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes. BMC Geriatrics, 22, Article 837. https://doi.org/10.1186/s12877-022-03539-w

Background
With an increasingly ageing population worldwide, the predominant attitude towards ageing is still negative. Negative stereotypes have detrimental effects on individuals’ physical and mental health. Evidence is required about factors that... Read More about A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes.

A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study (2022)
Journal Article
Lee, A. R., McDermott, O., Guo, B., Roe, J., & Orrell, M. (2022). A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study. JMIR Research Protocols, 11(7), Article e33881. https://doi.org/10.2196/33881

Background: With the rapid increase in the prevalence of dementia in the United Kingdom and beyond, the emotional, social, and economic burden on individuals, families, and health care services continues to rise. Currently, interventions that enable... Read More about A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study.

Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit (2022)
Journal Article
Coleston-Shields, D. M., Challis, D., Worden, A., Broome, E., Dening, T., Guo, B., Hoe, J., Lloyd-Evans, B., Moniz-Cook, E., Morris, S., Poland, F., Prothero, D., & Orrell, M. (2022). Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit. Trials, 23, Article 54. https://doi.org/10.1186/s13063-021-05995-y

Background: Improving care at home for people with dementia is a core policy goal in the dementia strategies of many European countries. A challenge to effective home support is the occurrence of crises in the care of people with dementia which arise... Read More about Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit.